Rhinopithecus bieti (black snub-nosed monkey): 108517816
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Entry
108517816 CDS
T04641
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04217
Necroptosis
rbb04380
Osteoclast differentiation
rbb04620
Toll-like receptor signaling pathway
rbb04621
NOD-like receptor signaling pathway
rbb04630
JAK-STAT signaling pathway
rbb04658
Th1 and Th2 cell differentiation
rbb04659
Th17 cell differentiation
rbb05145
Toxoplasmosis
rbb05160
Hepatitis C
rbb05161
Hepatitis B
rbb05162
Measles
rbb05164
Influenza A
rbb05165
Human papillomavirus infection
rbb05167
Kaposi sarcoma-associated herpesvirus infection
rbb05168
Herpes simplex virus 1 infection
rbb05169
Epstein-Barr virus infection
rbb05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
108517816 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
108517816 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
108517816 (TYK2)
04621 NOD-like receptor signaling pathway
108517816 (TYK2)
04658 Th1 and Th2 cell differentiation
108517816 (TYK2)
04659 Th17 cell differentiation
108517816 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
108517816 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
108517816 (TYK2)
05160 Hepatitis C
108517816 (TYK2)
05171 Coronavirus disease - COVID-19
108517816 (TYK2)
05164 Influenza A
108517816 (TYK2)
05162 Measles
108517816 (TYK2)
05168 Herpes simplex virus 1 infection
108517816 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
108517816 (TYK2)
05169 Epstein-Barr virus infection
108517816 (TYK2)
05165 Human papillomavirus infection
108517816 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
108517816 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rbb01001
]
108517816 (TYK2)
Enzymes [BR:
rbb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
108517816 (TYK2)
Protein kinases [BR:
rbb01001
]
Non-receptor tyrosine kinases
JAK family [OT]
108517816 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
108517816
NCBI-ProteinID:
XP_017711413
LinkDB
All DBs
Position
Unknown
AA seq
1190 aa
AA seq
DB search
MPLRHRGTTRGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI
AHKVGITPPCFNLFALFDAQAQVWLPPNYILEIPRDASLMLYFRMRFYFRNWHGMNPQEP
AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHFK
NESLGMAFLHLCHLALRRGVPLEEVAKKTSFKDCIPLSFRRQIRQHSALTRLRLRNVFRR
FLQDFQPDRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGEAP
TDPGPESAAGPPTHEVLVTGTGGIQWWPVQEEVNKEEGSSGGSGRNPKASLSGKKAKAHK
AIGQPVDRLREPLWAYFCDFRDITHVVLKERCVSIHRQDNKCLELSLPSRAAALSFVSLV
DGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP
YRLILTVAQRSQAPDGTQSLRLRKFPIEQQAGAFVLEGWGRSFPSIRELGAALQGCLLRA
GDDCFSLRRCCLPQPGETSNLIIMRGARASTRTLNLSQLSFHRVDQKEITQLSHLGQGTR
TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS
LMSQVSHVHLAFVHGICVRGPENIMVTEYMEHGPLDVWLRRERGHVPMAWKMVVAQQLAS
ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWMA
PECLPGGPNSLSIAMDKWGFGATLLEICFDGEAPLQSLSSSEKEHFYQRQHRLPEPSCPE
LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHTLPDLADVLIVNPDSSASDPTVFHKRYL
KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIEILRTLYHE
HIVKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQ
HYIHRDLAARNVLLDNDKLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK
FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGITQGQMTVLRLTELLERGERLPRP
DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYRGQAPSVFSVC
NT seq
3573 nt
NT seq
+upstream
nt +downstream
nt
atgcctttgcgccatcgggggacgaccaggggcagcaagcccgttggggatggagcccag
cccatggctgccatgggaggtctgaaggtgcttctgcactgggctggtccaggcggcgga
gagccctgggtcactttcagcgagtcatcactgacagctgaggaagtctgcatccacatc
gcacataaagtcggtatcactcctccttgtttcaatctcttcgccctcttcgatgctcag
gcccaagtctggttgcccccaaactacatcctagagatccccagggatgcaagcctgatg
ctgtatttccgcatgaggttttatttccggaactggcatggcatgaatcctcaggagccg
gctgtgtaccgttgtgggcccccaggaaccgaggcatcctcagatcagacagcacagggg
atgcaactcctggacccagcctcatttgagtacctctttgagcagggcaagcacgagttt
gtgaatgacgtggcatcactgtgggagctgtcgagcgaggaggagatccaccactttaag
aatgagagcctaggcatggcctttctgcacctctgtcaccttgctctccgccgtggtgtc
cccctggaggaggtggccaagaagaccagcttcaaggactgtatcccgctctccttccgt
cggcagatccggcagcacagcgccctgacccggctgcgccttcggaacgtcttccgcagg
ttcctgcaggacttccagccagacagactctcccagcagatggtcatggtcaaatacctg
gccacacttgaacggctggcaccccgctttggcacagagcgtgtgcctgtgtgccacctg
aggctgctggcccaggcagagggggagccctgctacatccgggacagtggggaggcccct
acagaccctggccccgagtctgctgctggacccccaacccatgaggtactggtgacaggc
actggtggcatccagtggtggccagtacaggaggaggtgaacaaggaggagggttctagt
ggcggcagcggcaggaaccccaaagccagcctgtctgggaagaaggccaaggctcacaag
gcaatcggccagccggtggacaggctgcgggagccactgtgggcctacttctgcgacttc
cgggacatcacccacgtggtgctgaaagagcgctgtgtcagcatccaccggcaggacaac
aagtgcctggagctgagcctgccttcccgggctgcggcgctgtccttcgtgtcgctggtg
gacggctatttccgcctgacggccgactccagccactacctgtgccacgaggtggctccc
ccacggctggtgatgagcatccaggatgggatccatggacccctgctggagccgtttgtg
caggccaagctgcggcccgaggacggcctgtacctcattcattggagcaccagccacccc
taccgcttgatcctcacagtggcccagcgtagccaggcaccagacggcacacagagcttg
cggctccggaagttccccattgagcagcaggctggggcctttgtgctggagggctggggc
cggtccttccccagcattcgggaacttggggccgccttgcagggctgcttgctgagggcc
ggggacgactgcttctctctgcgtcgctgttgcctgccccaaccaggagaaacctccaac
ctcatcatcatgcggggggctcgggccagcaccaggacactcaacctcagccagctcagc
ttccaccgggttgaccagaaggagatcacccagctgtcccacttgggccagggcacaagg
accaacgtgtacgagggccgcctgcgagtagagggcagtggagaccctgaggagggcaag
atggacgacgaggaccccctcgtccctggcagggaccgtgggcaggagctacgagtggtg
ctcaaagtgctggacccgagtcaccatgacattgccctggccttctatgagacagccagc
ctcatgagccaggtctcccacgtgcacctggccttcgtgcacggcatctgtgtgcgcggc
cctgaaaatatcatggtgacagagtacatggagcacggacccctggacgtgtggctacgg
agggagcggggccatgtgcccatggcttggaagatggtggtggcccagcagctggccagc
gccctcagctacctggagaacaagaacctggtacatggtaatgtgtgtggccggaacatc
ctgctggctcggctggggctggcagagggcacgagccccttcatcaagctgagtgatccc
ggcgtgggcctgggtgccctgtccagggaggagcgggtggagcggatcccctggatggcc
cccgaatgcctcccaggtgggcccaacagcctaagtattgccatggacaagtgggggttt
ggtgccaccctcctggagatctgctttgatggagaggcccctctgcagagcctcagctcc
tccgagaaggagcatttctaccagaggcagcaccggctgcccgagccctcctgcccagag
ctggccacactcaccagccagtgtctgacctatgagccaacccagaggccttcattccgc
accatcctgcgtgacctcacccggctgcagccccacactcttccagatcttgctgacgtc
ttgattgtgaacccggactcatcggcgtcagaccctacggttttccacaagcgctatttg
aaaaagatccgagatctgggcgagggtcacttcggcaaggtcagtttgtactgctacgat
ccgaccaacgacggcactggcgagatggtggcggtgaaagcccttaaggcagactgcggc
ccccagcaccgctcgggctggaagcaggagattgagattctgcgtacgctctatcacgag
cacatcgtcaagtacaagggctgctgcgaggaccaaggcgagaagtcgctgcagctggtc
atggagtacgtgcccctgggcagcctccgagactacctgccccggcacagcgtggggctg
gcccagctgctgctcttcgcccagcagatctgcgagggcatggcctatctgcacgcacag
cactacatccaccgagacctagccgcgcgcaacgtgctgctggacaacgacaagctggtc
aagatcggggactttggcctagccaaggccgtgcccgaaggccacgagtactaccgcgtg
cgcgaggatggggacagccccgtgttctggtatgccccagagtgcctgaaggagtataag
ttctactatgcgtccgatgtctggtccttcggggtgaccctgtatgagctgctgacgcac
tgtgactccagccagagcccccccacgaaattccttgagctcataggcatcacccagggt
cagatgacagttctgagactcaccgagttgctggaacgaggggagaggctgccacgaccc
gataaatgtccctgtgaggtctatcatctcatgaagaactgctgggagacagaggcgtcc
ttccgcccaaccttcgagaacctcatacccatcctgaagacagtccatgagaagtaccga
ggccaggccccttccgtgttcagtgtgtgctga
DBGET
integrated database retrieval system
