KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108520463
Entry
108520463         CDS       T04641                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04010  MAPK signaling pathway
rbb04022  cGMP-PKG signaling pathway
rbb04137  Mitophagy - animal
rbb04141  Protein processing in endoplasmic reticulum
rbb04151  PI3K-Akt signaling pathway
rbb04210  Apoptosis
rbb04211  Longevity regulating pathway
rbb04261  Adrenergic signaling in cardiomyocytes
rbb04668  TNF signaling pathway
rbb04720  Long-term potentiation
rbb04722  Neurotrophin signaling pathway
rbb04725  Cholinergic synapse
rbb04728  Dopaminergic synapse
rbb04911  Insulin secretion
rbb04912  GnRH signaling pathway
rbb04915  Estrogen signaling pathway
rbb04918  Thyroid hormone synthesis
rbb04922  Glucagon signaling pathway
rbb04925  Aldosterone synthesis and secretion
rbb04926  Relaxin signaling pathway
rbb04927  Cortisol synthesis and secretion
rbb04928  Parathyroid hormone synthesis, secretion and action
rbb04932  Non-alcoholic fatty liver disease
rbb04934  Cushing syndrome
rbb04935  Growth hormone synthesis, secretion and action
rbb05010  Alzheimer disease
rbb05012  Parkinson disease
rbb05014  Amyotrophic lateral sclerosis
rbb05020  Prion disease
rbb05022  Pathways of neurodegeneration - multiple diseases
rbb05030  Cocaine addiction
rbb05031  Amphetamine addiction
rbb05034  Alcoholism
rbb05161  Hepatitis B
rbb05163  Human cytomegalovirus infection
rbb05166  Human T-cell leukemia virus 1 infection
rbb05203  Viral carcinogenesis
rbb05207  Chemical carcinogenesis - receptor activation
rbb05215  Prostate cancer
rbb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    108520463 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108520463 (ATF4)
   04668 TNF signaling pathway
    108520463 (ATF4)
   04022 cGMP-PKG signaling pathway
    108520463 (ATF4)
   04151 PI3K-Akt signaling pathway
    108520463 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    108520463 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    108520463 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    108520463 (ATF4)
   04922 Glucagon signaling pathway
    108520463 (ATF4)
   04912 GnRH signaling pathway
    108520463 (ATF4)
   04915 Estrogen signaling pathway
    108520463 (ATF4)
   04926 Relaxin signaling pathway
    108520463 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    108520463 (ATF4)
   04918 Thyroid hormone synthesis
    108520463 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    108520463 (ATF4)
   04925 Aldosterone synthesis and secretion
    108520463 (ATF4)
   04927 Cortisol synthesis and secretion
    108520463 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    108520463 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    108520463 (ATF4)
   04728 Dopaminergic synapse
    108520463 (ATF4)
   04720 Long-term potentiation
    108520463 (ATF4)
   04722 Neurotrophin signaling pathway
    108520463 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    108520463 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    108520463 (ATF4)
   05203 Viral carcinogenesis
    108520463 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    108520463 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    108520463 (ATF4)
   05161 Hepatitis B
    108520463 (ATF4)
   05163 Human cytomegalovirus infection
    108520463 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108520463 (ATF4)
   05012 Parkinson disease
    108520463 (ATF4)
   05014 Amyotrophic lateral sclerosis
    108520463 (ATF4)
   05020 Prion disease
    108520463 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    108520463 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    108520463 (ATF4)
   05031 Amphetamine addiction
    108520463 (ATF4)
   05034 Alcoholism
    108520463 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108520463 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    108520463 (ATF4)
   04934 Cushing syndrome
    108520463 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rbb03000]
    108520463 (ATF4)
Transcription factors [BR:rbb03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    108520463 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF3450 DUF4407 Laminin_II Asd-4 Nop53 AAA_13 OVT1 KIF21A
Other DBs
NCBI-GeneID: 108520463
NCBI-ProteinID: XP_017715333
UniProt: A0A2K6KZK8
LinkDB
Position
Unknown
AA seq 351 aa
MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLAVEGLVSPSNNGKEDAFSGTDWMLEKMDLKEFDFDALLGIDDLETMPDDLLTTLDDTC
DLFAPLVQETNKEPPQTVNPIGHLPESLTKPDQVAPFTFLQPLSLSPGVLSSTPDHSFSL
ELGSEVDITEGDRKPDSTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRG
SPNRSLPSPGVLCGSARPKPYDPPGEKMVETKVKGEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgaccgaaatgagcttcctgagcagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaagaaagcctaggtctcttagatgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggaggggttggtcagtccctctaacaacggcaaggaggatgccttctcc
gggacagattggatgttggagaaaatggatttgaaggagttcgactttgatgccctgttg
ggtatagatgacctggaaaccatgccagatgaccttttgaccacattggatgacacgtgt
gatctctttgcccccctagtccaggagactaacaaggagcccccccagacagtgaaccca
attggccatctcccagaaagtttaacaaaacccgaccaggttgcccccttcaccttcttg
caacctctttccctttccccaggggtcctgtcctccactccagatcattcctttagttta
gagctgggcagtgaagtggatatcactgaaggagataggaagccagactccactgcttat
gttgccatgatccctcagtgcataaaggaggaagacaccccctcagataatgatagtggc
atctgtatgagcccagagtcctatctgggctctcctcagcatagcccctctaccaggggc
tctccaaataggagcctcccatctccaggtgttctgtgtggttctgcccgccccaaacct
tacgaccctcctggagagaagatggtagaaacaaaagtaaagggtgagaaactggataag
aagctgaaaaaaatggagcaaaacaagacagcagccactaggtaccgccagaagaagagg
gcggagcaggaggctctcactggcgagtgcaaagagctggaaaagaagaatgaggctctg
aaagagagggcggattccctagccaaggagatccagtacctgaaagatttgatagaagag
gtccgcaaggcaagggggaagaaaagggtcccctag

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