Rhinopithecus bieti (black snub-nosed monkey): 108520869
Help
Entry
108520869 CDS
T04641
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1
KO
K03099
son of sevenless
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01521
EGFR tyrosine kinase inhibitor resistance
rbb01522
Endocrine resistance
rbb04010
MAPK signaling pathway
rbb04012
ErbB signaling pathway
rbb04014
Ras signaling pathway
rbb04062
Chemokine signaling pathway
rbb04068
FoxO signaling pathway
rbb04072
Phospholipase D signaling pathway
rbb04150
mTOR signaling pathway
rbb04151
PI3K-Akt signaling pathway
rbb04510
Focal adhesion
rbb04540
Gap junction
rbb04630
JAK-STAT signaling pathway
rbb04650
Natural killer cell mediated cytotoxicity
rbb04660
T cell receptor signaling pathway
rbb04662
B cell receptor signaling pathway
rbb04664
Fc epsilon RI signaling pathway
rbb04714
Thermogenesis
rbb04722
Neurotrophin signaling pathway
rbb04810
Regulation of actin cytoskeleton
rbb04910
Insulin signaling pathway
rbb04912
GnRH signaling pathway
rbb04915
Estrogen signaling pathway
rbb04917
Prolactin signaling pathway
rbb04926
Relaxin signaling pathway
rbb04935
Growth hormone synthesis, secretion and action
rbb05034
Alcoholism
rbb05160
Hepatitis C
rbb05161
Hepatitis B
rbb05163
Human cytomegalovirus infection
rbb05165
Human papillomavirus infection
rbb05200
Pathways in cancer
rbb05205
Proteoglycans in cancer
rbb05206
MicroRNAs in cancer
rbb05207
Chemical carcinogenesis - receptor activation
rbb05208
Chemical carcinogenesis - reactive oxygen species
rbb05210
Colorectal cancer
rbb05211
Renal cell carcinoma
rbb05213
Endometrial cancer
rbb05214
Glioma
rbb05215
Prostate cancer
rbb05220
Chronic myeloid leukemia
rbb05221
Acute myeloid leukemia
rbb05223
Non-small cell lung cancer
rbb05224
Breast cancer
rbb05225
Hepatocellular carcinoma
rbb05226
Gastric cancer
rbb05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108520869 (SOS1)
04012 ErbB signaling pathway
108520869 (SOS1)
04014 Ras signaling pathway
108520869 (SOS1)
04630 JAK-STAT signaling pathway
108520869 (SOS1)
04068 FoxO signaling pathway
108520869 (SOS1)
04072 Phospholipase D signaling pathway
108520869 (SOS1)
04151 PI3K-Akt signaling pathway
108520869 (SOS1)
04150 mTOR signaling pathway
108520869 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
108520869 (SOS1)
04540 Gap junction
108520869 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
108520869 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
108520869 (SOS1)
04660 T cell receptor signaling pathway
108520869 (SOS1)
04662 B cell receptor signaling pathway
108520869 (SOS1)
04664 Fc epsilon RI signaling pathway
108520869 (SOS1)
04062 Chemokine signaling pathway
108520869 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
108520869 (SOS1)
04912 GnRH signaling pathway
108520869 (SOS1)
04915 Estrogen signaling pathway
108520869 (SOS1)
04917 Prolactin signaling pathway
108520869 (SOS1)
04926 Relaxin signaling pathway
108520869 (SOS1)
04935 Growth hormone synthesis, secretion and action
108520869 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
108520869 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
108520869 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108520869 (SOS1)
05206 MicroRNAs in cancer
108520869 (SOS1)
05205 Proteoglycans in cancer
108520869 (SOS1)
05207 Chemical carcinogenesis - receptor activation
108520869 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
108520869 (SOS1)
05231 Choline metabolism in cancer
108520869 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
108520869 (SOS1)
05225 Hepatocellular carcinoma
108520869 (SOS1)
05226 Gastric cancer
108520869 (SOS1)
05214 Glioma
108520869 (SOS1)
05221 Acute myeloid leukemia
108520869 (SOS1)
05220 Chronic myeloid leukemia
108520869 (SOS1)
05211 Renal cell carcinoma
108520869 (SOS1)
05215 Prostate cancer
108520869 (SOS1)
05213 Endometrial cancer
108520869 (SOS1)
05224 Breast cancer
108520869 (SOS1)
05223 Non-small cell lung cancer
108520869 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
108520869 (SOS1)
05160 Hepatitis C
108520869 (SOS1)
05163 Human cytomegalovirus infection
108520869 (SOS1)
05165 Human papillomavirus infection
108520869 (SOS1)
09165 Substance dependence
05034 Alcoholism
108520869 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108520869 (SOS1)
01522 Endocrine resistance
108520869 (SOS1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
108520869
NCBI-ProteinID:
XP_017715896
LinkDB
All DBs
Position
Unknown
AA seq
1231 aa
AA seq
DB search
MLCQAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEV
LGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFH
QDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLF
SANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYES
YARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELL
KQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQL
AIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQ
PRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNW
MAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAG
IPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTE
ADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEF
IGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLL
TLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEK
CIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQ
KKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELIN
FSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIE
PRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTA
SAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSRCKNSKCIKIMSKHLDSPPAI
PPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKS
DHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHI
PKLPPKTYKREHTHPSMHRDGPPLLENAHSS
NT seq
3696 nt
NT seq
+upstream
nt +downstream
nt
atgctatgccaagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagt
ttccctcatccaattgataagtgggcaatagctgatgcccaatcagctattgaaaagagg
aagcgaagaaaccctttatctctcccagtagaaaaaatccatcctttattaaaggaggtc
ctaggttataaaattgaccatcaggtttctgtttacatagtagcagtcttagaatacatt
tcagcagacattttaaagctggttgggaattatgtaagaaatatacggcattatgaaatt
acaaaacaagatattaaagtggcaatgtgtgctgacaaggtattgatggatatgtttcat
caagatgtagaagatattaatatattatctttaactgatgaagagccttccacctcagga
gaacaaacttactatgatttggtaaaagcatttatggcagaaattcgacaatatataagg
gaactaaatctaattataaaagtttttagagagccctttgtctccaattcaaaattgttt
tcagctaatgatgtagaaaatatatttagtcgtatagtagatatacatgaacttagtgta
aagttactgggccatatagaagatacagtagaaatgacagatgaaggcagtccccatcca
ctagtaggaagctgctttgaagacttagcagaggaactggcatttgatccgtatgaatcg
tatgctcgagatattttgcgacctggttttcatgatcgtttccttagtcagttatcaaag
cctggggcagcactttatttgcagtcaataggcgaaggtttcaaagaagctgttcaatat
gttttacccaggctgcttctggcccctgtttaccactgtctccattactttgaacttttg
aagcagttagaagaaaaaagtgaagatcaagaagacaaggaatgtttaaaacaagcaata
acagctttgcttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaa
cgaagactgagtgaatctgcatgtcggttttatagtcaacaaatgaaggggaaacaacta
gcaatcaagaaaatgaatgagattcagaagaatattgatggttgggagggaaaagacatt
ggacagtgttgcaatgaatttataatggaaggaactcttacacgtgtaggagccaaacat
gagagacacatatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcag
ccaagacttcctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgcga
aaggtacaaatcaatgataaagatgacaccaatgaatacaagcatgcttttgaaataatt
ttaaaagatgaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattgg
atggcagcactgatatctttacagtaccggagtacactggaaaggatgcttgatgtaaca
atgctacaagaagagaaagaggagcagatgaggctgcctagtgctgatgtttatagattt
gcggagcctgactctgaagagaatattatatttgaagagaacatgcagcccaaggctgga
attccaattatcaaagcaggaactgttattaaacttatagagaggcttacgtaccatatg
tacgcagatcccaattttgttcggacatttcttacaacatacagatccttttgcaaacct
caagaactactgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaa
gctgatcgcatagctatagagaatggagatcaacccttgagtgcagaactgaaaagattt
agaaaagaatatatacagcctgtgcaactgcgagtattaaatgtatgtcggcactgggta
gagcaccacttctatgattttgaaagagatgcatatcttttgcaacgaatggaagaattt
attggaacagtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatc
caaaggaaaaaaattgcaagagacaatggaccaggtcataatattacatttcagagttca
cctcccacagttgagtggcatataagcagacctgggcacatagagactttcgacctgctc
accttacacccaatagaaattgctcgacaactcactttacttgaatcagatctataccga
gctgtacagccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaac
tctccgaatcttctgaaaatgattcgacataccaccaacctcactctgtggtttgagaaa
tgtattgtagaaactgaaaatttagaagaaagagtagctgtggtgagtcgaataattgag
attctacaagtctttcaagagttgaacaactttaatggtgtccttgaggttgtcagtgct
atgaattcctcacctgtttacagactagaccacacatttgagcaaataccaagtcgccag
aagaaaattttagaagaagctcatgaattgagtgaagatcactataagaaatatttggca
aaactcaggtctattaatccaccatgtgtgcctttctttggaatttatctcactaatatc
ttgaaaacagaagaaggcaaccctgaggtcctaaaaagacatggaaaagagcttataaac
tttagcaaaaggagaaaagtagcagaaataacaggagagatccagcagtaccaaaatcag
ccttactgtttacgagtagaatcagatatcaaaagattctttgaaaacttgaatccgatg
ggaaacagcatggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaa
ccacgaaaccctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatct
cctggtgttcgtccatcaaacccaagaccaggtaccatgaggcatcccacacctctgcag
caggagccaaggaaaattagttatagtaggatccctgaaagtgaaacagaaagtacagca
tctgcaccaaattctccaagaacaccgttaacacctccgcctgcttctggtgcttccagt
accacagatgtttgcagtgtatttgattccgatcattcgagcccttttcactcaagtagg
tgcaaaaattctaagtgcattaagattatgtctaagcatttggacagccccccagccatt
cctcctaggcaacccacatcaaaagcctattcaccacgatattcaatatcagaccggacc
tctatctcagaccctcctgaaagccctcccttattaccaccacgagaacctgtgaggaca
cctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaaaaaagt
gaccatggcaatgccttcttcccaaacagcccatccccctttacaccacctcctcctcaa
acaccttctcctcacggcacaagaaggcatctgccatcaccaccattgacacaagaagtg
gaccttcattccattgctgggccgcctgttcctccacgacaaagcacttctcaacatatc
cctaaactccctccaaaaacttacaaaagggagcacacacacccatccatgcacagagat
ggaccaccactgttggagaatgcccattcttcttga
DBGET
integrated database retrieval system
