Rhinopithecus bieti (black snub-nosed monkey): 108521233
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Entry
108521233 CDS
T04641
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00562
Inositol phosphate metabolism
rbb01100
Metabolic pathways
rbb04014
Ras signaling pathway
rbb04015
Rap1 signaling pathway
rbb04020
Calcium signaling pathway
rbb04024
cAMP signaling pathway
rbb04070
Phosphatidylinositol signaling system
rbb04919
Thyroid hormone signaling pathway
rbb04933
AGE-RAGE signaling pathway in diabetic complications
rbb05205
Proteoglycans in cancer
Module
rbb_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
108521233 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
108521233 (PLCE1)
04015 Rap1 signaling pathway
108521233 (PLCE1)
04020 Calcium signaling pathway
108521233 (PLCE1)
04070 Phosphatidylinositol signaling system
108521233 (PLCE1)
04024 cAMP signaling pathway
108521233 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
108521233 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
108521233 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
108521233 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rbb04131
]
108521233 (PLCE1)
Enzymes [BR:
rbb01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
108521233 (PLCE1)
Membrane trafficking [BR:
rbb04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
108521233 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
108521233 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
108521233
NCBI-ProteinID:
XP_017716455
LinkDB
All DBs
Position
Unknown
AA seq
1765 aa
AA seq
DB search
MEEGIRDCGLPGVEERQPGPSVANSNTLPSSSAGISKELIDLQPLIQFPEEVASILMEQE
QSIYRRVLPVDYLCFLTRDLGTPECQRSLPCLKASISASILTTQNGEHNALEDLVMRFNE
VSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFM
DQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGL
MKICPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCSRSLET
DEEDSPSEGNSSRKSSLKDKSRWQFIIGDLLDSDNDIFEQSKEYDSHGSEDSQKAFDHGT
ELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTASPAS
TKAKLGVLYNTAEPGKFPLLGNAGLSGLTEGVLDLFAVKAVYMGHPGIDIHTVCVQNKLG
SMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQWL
RKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPSMQRNNTLGIST
TKKKKKILMRGESGEATDDEMATRKAKMHKECRSRSGSDPQDINEQEESEVNTIASPPNP
LPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLPSSNKSPSSAWSSSSWHGRIKGGMKGF
QSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCSRSGSESAPLYTNLTIDEN
TSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFG
VGILQLNDFLVNCQGEHCTYDEILSIIQKFEPNISMCHQGLMSFEGFARFLMDKENFASK
NDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDG
DDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKT
VFGEKLVAKFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQ
AQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYSEEI
PKRIKKADNSAYNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGLSTL
NASGSNRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLNPTT
SLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPIM
FWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDL
DSMDPVVYSLTIVSGPGRGAPVWLCHPGWSAVERLTVSLSNMLPGYRHLQLRNLHNEVLE
ISSLFINSRRMEENSSGSTMSASSMFNTEERKCLQTHRVTVHGVPGPEPFTVFTINGGTK
AKQLLQQILTTEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSW
FPEEGYVGRIVLKTQQENLEEKNTVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPR
VSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKSTTPKSSQRVLLDQEC
VFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQARGLTSPSQLLT
SESIQTKEEKPVGGLSSNDTMDYRQ
NT seq
5298 nt
NT seq
+upstream
nt +downstream
nt
atggaagaaggaattagggactgtgggctacctggtgtagaagaacgccagccaggcccc
tctgtggccaattccaacaccctcccttcaagttcagctgggatcagcaaggagctgatc
gatctgcagcctctcatccagttcccagaggaagtcgccagcatcctgatggagcaggag
cagagtatttaccgcagggtcttgccggtcgactacctttgcttcttaacacgggacttg
ggcactcccgaatgccagaggtccctgccctgcctcaaagcatccatctcagcatcaatt
cttaccactcagaatggagagcacaatgcccttgaagatctggtgatgaggtttaatgag
gtgagctcctgggtgacgtggctgatcctcacggcaggctccatggaggagaagcgagaa
gtcttttcatatttggtgcatgtggccaaatgctgctggaacatgggcaactacaacgct
gtcatggagttcttggctggcctcaggtcaagaaaagttttaaaaatgtggcagtttatg
gaccagtctgatattgagaccatgaggagcctgaaggatgctatggcccagcatgagtcc
tcttgtgagtacagaaaggtggtgacacgtgccctgcacatccctggctgtaaggtggtt
ccgttctgtggagtgtttctgaaggagctctgtgaagtgcttgacggcgcctctggcctc
atgaagatatgcccgcggtacaattcccaagaagaaactttagagtttgtagcagattac
agtggacaagataatttcttacaacgagtgggacaaaatggcttaaagaattcggagaaa
gagtccactgtcaacagcatctttcaggtcatccggagctgcagtcgaagtctggagaca
gatgaggaggacagccccagtgaagggaacagctccaggaaaagttccttgaaggataaa
agccgatggcagtttataattggagatttgttggattcagacaatgatatctttgagcaa
tccaaagaatacgactctcatggttcagaggactcacagaaggcctttgaccatgggacg
gagctcatcccgtggtatgtgctgtccatccaagccgatgtgcaccagttcctgctgcag
ggggccacggtcatccactatgaccaggacacacacctctctgcccgatgcttcctccag
cttcagcctgacaatagcaccttgacctgggtaaagcccacaactgcctccccagctagc
actaaagcaaaacttggtgtactttataacacagctgagcctggaaaattcccactactg
ggcaatgctggattaagtggcctgacggaaggggtcttggatctttttgcagtgaaggct
gtatacatgggccaccctggcattgatatacacactgtgtgtgttcagaacaaactgggt
agcatgttcctgtcagagactggtgtgacactgctctatgggcttcagaccacggacaat
agattattgcacttcgtggcaccaaagcacacagctaaaatgctcttcagcggattgttg
gaactcactagagctgtgagaaagatgaggaaattccctgaccaaagacagcagtggctg
cggaaacagtacgtcagcctctatcaggaggatggacggtatgaaggcccaactttggct
catgctgtggagttgtttggtggcagacgatggagtgctcgaaaccccagccccggcaca
tctgcaaagaatgctgagaagcccagtatgcagagaaacaacaccctgggcataagcact
accaagaaaaagaagaaaatcctcatgaggggtgagagtggagaggcaactgacgatgag
atggcaacccgaaaggccaagatgcacaaagagtgtcgaagccggagtggttctgatcct
caagacattaatgaacaagaagaatcggaggtgaataccatcgctagcccgccaaacccc
ctcccttccagaagagcccactctttgaccacagctgggtcccccaacttggctgccggg
acgtcatctcccatcaggccagtgtcctcccctgtgctgccttcttcaaacaagagcccg
tccagtgcttggagcagtagtagctggcatgggcggatcaaaggcggcatgaagggattt
cagagcttcatggtttcagacagcaacatgagttttgttgaatttgttgagctgttcaaa
tcattcagtgtcaggagccgcaaggacctgaaggatctgtttgatgtctacgcagtgccc
tgcagccgatctggatccgagtcagccccgctctacaccaacctgacgattgatgaaaac
accagcgatcttcagcctgacctagatctgttgaccagaaatgtctcagatttggggttg
ttcatcaagagtaaacagcagctatcggacaaccagaggcagatatctgatgccattgct
gctgcaagcatcgtgacaaatggcactgggattgagagcacatctctgggcattttcggg
gtgggcatacttcagctcaatgatttcctcgtgaattgccaaggagaacactgcacttat
gatgaaatcctcagcatcatccagaagtttgaacctaacatcagtatgtgtcatcaggga
ctaatgtcatttgaagggtttgcaaggtttctgatggataaagaaaattttgcctcaaaa
aatgatgagtcacaggagaacattaaagaactacagctacccctctcatactattacatc
gaatcttcgcacaatacctacctcacgggccatcagctcaaaggagaatcctcagtagaa
ctctacagccaggtcctcttgcaaggctgtcgaagtgtagaattggactgctgggacgga
gacgatgggatgcccatcatttatcatggacatacactgacaaccaagatccccttcaag
gaagtggtcgaagccattgatcgcagtgccttcatcaactctgacctgccaatcatcata
tcgattgagaatcactgttcattgcctcagcaacgaaaaatggcagaaattttcaagact
gtgtttggagaaaagctggtggctaaattcttatttgagactgatttctcagatgatcca
atgcttccttcacctgaccaactcagaaggaaagtgcttcttaaaaacaagaagctaaaa
gcccatcagacgccagtggatatcttaaagcaaaaggctcatcagttagcatctatgcaa
gcgcaggcttataatggtgggaatgccaaccccccacctgccaataatgaggaagaggaa
gatgaggaggacgaatatgattatgactatgaatccctttctgatgacaacattctggaa
gacagacctgaaaataaatcatgtaatgacaagcttcagtttgagtatagtgaagaaatc
cccaagaggataaagaaggcagataactctgcttacaacaaaggaaaggtttatgatatg
gaactgggagaagaattttatcttgatcagaataaaaaggaaagcagacagattgcacca
gagctttctgaccttgtaatctattgtcaagcagtaaaatttccaggactgtcaactcta
aatgcatctggctctaacagaggaaaggaaaggaaaagcaggaagtccatttttggcaac
aatccgggcagaatgagcccaggggagacagcatcatttaacaaaacatctggaaaaagt
tcctgtgaaggcattcgacagacctgggaggaatcttcttcccctctcaacccaaccaca
tccctcagtgctatcattagaactcctaaatgttatcatatctcgtcgctgaatgaaaat
gccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcataccgcctgtcag
ctgctgagaacttaccctgctgccacccgcatcgactcctccaacccgaaccccatcatg
ttctggctccatgggatacagctcgtggcactcaactaccagaccgatgatctcccttta
catttaaatgctgcaatgtttgaggcaaatggtggttgtggttatgttttgaaacctcca
gttctgtgggacaagaactgcccgatgtatcagaagttttctccactggaaagagatctg
gacagcatggatcctgtagtctattctttaactattgtctctggtccgggaagaggggcc
ccagtctggctgtgtcacccaggctggagtgcagtggagcgattgacagtttccctttct
aacatgctcccaggatatcgacatcttcagctgcgaaaccttcacaatgaagtcttggaa
atctctagtctattcattaacagcagaaggatggaagaaaattcctctggcagtaccatg
tcagcctcttcgatgtttaatacagaagaaagaaaatgtttgcagactcacagagtcacg
gtgcatggggtcccagggccagagccctttactgttttcactattaatggaggcaccaag
gcaaagcagcttctgcagcaaattctgacaactgaacaagacatcaaacctgttaccaca
gactattttttgatggaagaaaaatattttatatctaaagaaaagaatgaatgtaggaaa
caaccattccagagagccattggtccagaagaggagatcatgcaaattttaagcagctgg
tttccagaagagggatatgtgggcaggattgtcttaaaaacccagcaggaaaacctagaa
gagaaaaacactgttcaagatgacaaagaagtgatcttgagctctgaggaggagagtttc
tttgtccaagtgcatgatgtttctccagagcaacctcgaacagtcatcaaagcaccccgc
gtcagcaccgcacaggatgtcattcagcagaccttatgcaaagccaaatattcctacagc
atcctgagcaaccccaatccgagtgactatgtgcttctggaagaggtggtgaaagacact
accaacaagaagtctaccacacccaagtcctctcagcgggtccttctggatcaggagtgt
gtgtttcaagcccaaagcaagtggaaaggtgcaggaaaattcatccttaagctaaaggag
caagtgcaggcatctcgagaagataaaaagaaaggcatttcttttgcaagtgaactcaag
aagctcaccaagtcaactaaacaggcccgaggacttacatcaccttctcagctcttgacc
tcagaaagtatccaaaccaaggaggagaaacctgtgggtggcctgtcctccaatgacaca
atggattaccgacagtga
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integrated database retrieval system
