KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108521513
Entry
108521513         CDS       T04641                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X1
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04010  MAPK signaling pathway
rbb04015  Rap1 signaling pathway
rbb04218  Cellular senescence
rbb04620  Toll-like receptor signaling pathway
rbb04664  Fc epsilon RI signaling pathway
rbb04668  TNF signaling pathway
rbb04714  Thermogenesis
rbb04750  Inflammatory mediator regulation of TRP channels
rbb04912  GnRH signaling pathway
rbb04935  Growth hormone synthesis, secretion and action
rbb04936  Alcoholic liver disease
rbb05014  Amyotrophic lateral sclerosis
rbb05022  Pathways of neurodegeneration - multiple diseases
rbb05132  Salmonella infection
rbb05135  Yersinia infection
rbb05145  Toxoplasmosis
rbb05161  Hepatitis B
rbb05169  Epstein-Barr virus infection
rbb05170  Human immunodeficiency virus 1 infection
rbb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rbb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108521513 (MAP2K3)
   04015 Rap1 signaling pathway
    108521513 (MAP2K3)
   04668 TNF signaling pathway
    108521513 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    108521513 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    108521513 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    108521513 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    108521513 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    108521513 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    108521513 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    108521513 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108521513 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    108521513 (MAP2K3)
   05161 Hepatitis B
    108521513 (MAP2K3)
   05169 Epstein-Barr virus infection
    108521513 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    108521513 (MAP2K3)
   05135 Yersinia infection
    108521513 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    108521513 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    108521513 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    108521513 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108521513 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    108521513 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rbb01001]
    108521513 (MAP2K3)
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     108521513 (MAP2K3)
Protein kinases [BR:rbb01001]
 Serine/threonine kinases: STE group
  STE7 family
   108521513 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 Choline_kinase APH RIO1 DUF4344
Other DBs
NCBI-GeneID: 108521513
NCBI-ProteinID: XP_017716867
UniProt: A0A2K6L236
LinkDB
Position
Unknown
AA seq 347 aa
MESPASSQPASMPQSKGKSKRKKDLRISCMSKPPAPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgcctcaagccagcccgccagcatgccccagtccaaaggaaaatccaag
aggaagaaggatctacggatatcctgcatgtccaagccacccgcgcctaaccccacaccc
ccccggaacttggactcccggaccttcatcaccattggagacagaaactttgaggtggaa
gctgatgacttggtgaccatctcggaactgggccgtggagcctatggagtggtggagaag
gtgcggcacgcccagagcggcaccatcatggccgtgaagcggatccgggccactgtgaac
tcacaggagcagaagcggctgctcatggacctggacatcaacatgcgcacagtcgactgc
ttctacactgtcaccttctatggggcactattcagagagggagatgtgtggatctgcatg
gagctcatggacacatccctggacaagttctaccggaaggtgctggataaaaacatgaca
attccagaggacatcctcggggagattgctgtgtctatcgtgcgggccctggagcatctg
cacagcaagctgtcggtgatccacagagatgtgaagccctccaatgtccttatcaacaag
gagggccatgtgaagatgtgtgactttggcatcagtggttacttggtggactctgtggcc
aagacgatggatgctggctgcaagccctacatggcccctgagaggatcaacccggagctg
aaccagaagggctacaatgtcaagtccgacgtctggagcctgggcattaccatgattgag
atggccatcctgcggttcccttatgagtcctgggggaccccgttccagcagctgaagcag
gtggtggaggagccgtccccccagctcccagccgaccgtttctcccccgagtttgtggac
ttcactgctcagtgcctgaggaagaaccccgcagagcgtatgagctacctggagctgatg
gagcaccccttcttcaccttgcacaaaaccaagaagacagacattgctgccttcgtgaag
gagatcctgggcgaagactcatag

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