KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108523026
Entry
108523026         CDS       T04641                                 
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein kinase JAK2-like
  KO
K04447  Janus kinase 2 [EC:2.7.10.2]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01521  EGFR tyrosine kinase inhibitor resistance
rbb04062  Chemokine signaling pathway
rbb04081  Hormone signaling
rbb04148  Efferocytosis
rbb04151  PI3K-Akt signaling pathway
rbb04217  Necroptosis
rbb04550  Signaling pathways regulating pluripotency of stem cells
rbb04630  JAK-STAT signaling pathway
rbb04658  Th1 and Th2 cell differentiation
rbb04659  Th17 cell differentiation
rbb04725  Cholinergic synapse
rbb04917  Prolactin signaling pathway
rbb04920  Adipocytokine signaling pathway
rbb04933  AGE-RAGE signaling pathway in diabetic complications
rbb04935  Growth hormone synthesis, secretion and action
rbb05140  Leishmaniasis
rbb05145  Toxoplasmosis
rbb05152  Tuberculosis
rbb05161  Hepatitis B
rbb05164  Influenza A
rbb05167  Kaposi sarcoma-associated herpesvirus infection
rbb05168  Herpes simplex virus 1 infection
rbb05200  Pathways in cancer
rbb05207  Chemical carcinogenesis - receptor activation
rbb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rbb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    108523026
   04151 PI3K-Akt signaling pathway
    108523026
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    108523026
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    108523026
  09143 Cell growth and death
   04217 Necroptosis
    108523026
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    108523026
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    108523026
   04659 Th17 cell differentiation
    108523026
   04062 Chemokine signaling pathway
    108523026
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    108523026
   04917 Prolactin signaling pathway
    108523026
   04935 Growth hormone synthesis, secretion and action
    108523026
  09156 Nervous system
   04725 Cholinergic synapse
    108523026
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108523026
   05207 Chemical carcinogenesis - receptor activation
    108523026
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108523026
  09172 Infectious disease: viral
   05161 Hepatitis B
    108523026
   05164 Influenza A
    108523026
   05168 Herpes simplex virus 1 infection
    108523026
   05167 Kaposi sarcoma-associated herpesvirus infection
    108523026
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    108523026
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    108523026
   05140 Leishmaniasis
    108523026
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108523026
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    108523026
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    108523026
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rbb01001]
    108523026
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     108523026
Protein kinases [BR:rbb01001]
 Non-receptor tyrosine kinases
  JAK family [OT]
   108523026
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 Jak1_Phl SH2 ABC1 FERM_C_FAK1 Kinase-like RIO1
Other DBs
NCBI-GeneID: 108523026
NCBI-ProteinID: XP_017718969
LinkDB
Position
Unknown
AA seq 923 aa
MSYLFAQWRHDFVHGWIKVPVTHETQEECLGMAVLDMMRIAKENDQTPLAIYNSISYKTF
LPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQSAFYTEK
FEVKEPGSGPSGEEIFATIIITGNGGIQWSRGKHKESETLTEQDLQLYCDFPNIIDVSIK
QANQEGSDESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAP
PTVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEY
KHCLITKNENEEYNLSGTKKNFNSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKXKSNL
LVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKXFKGIRREVGD
YGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGEENILVAGVX
XKFGSLDTYLKTESKIVXIYVALELQNKLAWAMHFLEENTLIHGNVCAKNILLIREEDRK
TGNPPFIKLSESGISITVLPKEVLQERIPWVPPECIENPXNLNLATDKWSFGTTLWEICS
GGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSL
FTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRY
DPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLI
MEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENEN
RVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELF
TYIEKSKSPPAVSVLFIYFQFFV
NT seq 2769 nt   +upstreamnt  +downstreamnt
atgtcttacctctttgctcagtggcggcatgattttgtgcatggatggataaaagtacct
gtgactcatgaaacacaggaagaatgtcttgggatggcagtgttagatatgatgagaata
gccaaagaaaatgatcaaaccccactggccatctataactctatcagctacaagacattc
ttaccaaaatgtattcgagcaaagatccaagactatcatattttgacaaggaagcgaata
aggtacagatttcgcagatttattcagcagttcagccaatgcaaagccactgccagaaac
ttgaaacttaagtatcttataaatctggaaaccctgcagtctgccttctacacagagaaa
tttgaagtaaaagaacctggaagtggtccttcaggtgaggagatttttgcaaccattata
ataactggaaacggtggaattcagtggtcaagagggaaacataaagaaagtgagacactg
acagaacaggatttacagttatattgcgattttcctaatattattgatgtcagtattaag
caagcaaaccaagagggttcagatgaaagccgagttgtaactatccataagcaagatggt
aaaaatctggaaattgaacttagctcattaagggaagctttgtctttcgtgtcattaatt
gatgggtattatagattaactgcagatgcacatcattacctctgtaaagaagtagcacct
ccaacagtgcttgaaaatatacaaagcaactgtcatggcccaatttcgatggattttgcc
attagtaaactgaagaaagcaggtaatcagactggactgtatgtacttcgatgcagtcct
aaggactttaataaatattttctgacttttgctgtcgagcgagaaaatgtcattgaatat
aaacactgtttgattacaaaaaatgagaatgaagagtacaacctcagtgggacaaagaag
aacttcaacagtcttaaagatcttttgaattgttaccagatggaaaccgttcgctcagac
aatataattttccagtttactaagtgctgtcccccaaagccaaaagntaaatcaaacctt
ctagtcttcagaacgaatggtgtttctgatgtaccaacctcaccaacattacagaggcct
actcatatgaaccaaatggtgtttcacaaaatcagaaatgaagatttgatatttaatgaa
agccttggccaaggcacttttacaaagnattttaaaggcatacgaagagaagtaggagac
tatggtcaactgcatgaaacagaagttcttttaaaagttctggataaagcacatagaaac
tattcagagtctttctttgaagcagcaagcatgatgagcaagctttctcacaagcatttg
gttttaaattatggagtatgtgtctgtggagaggagaatattctggttgcaggagtttga
taaaaatttggatcactagatacatacctgaaaacagaatcaaaaattgtataaatatat
gtggcacttgagttgcaaaacaagttggcatgggccatgcattttctagaagaaaacacc
cttattcatgggaatgtgtgcgccaaaaatattctacttatcagagaagaagacaggaag
acaggaaatcctcctttcatcaaacttagtgagtctggcattagtattacagttttgcca
aaagaagttcttcaggagagaataccatgggtaccacctgaatgcattgaaaatcctnaa
aatttaaatttggcaacagacaaatggagttttggtaccactttgtgggaaatctgcagt
ggaggagataaacctctaagtgctctggattctcaaagaaagctgcaattttatgaagat
aggcaccagcttcctgcaccaaagtgggcagaattagcaaaccttataaataattgtatg
gattatgagccagatttcaggccttctttcagagccatcatacgagatcttaacagtttg
tttactccagattatgaactattaacagaaaatgacatgttaccaaatatgaggataggt
gccctagggttttctggtgcctttgaagacagggatcctacacagtttgaagagagacat
ttgaaatttctacagcaactcggcaagggtaattttgggagtgtggagatgtgccggtat
gaccctctacaggacaacactggggaggtggtggctgtaaaaaagcttcagcatagtact
gaagagcacctgagagactttgaaagggaaattgaaatcctgaaatccctacagcatgac
aacattgtaaagtacaagggagtgtgctacagtgctggtcggcgtaatctaaaattaatt
atggaatatttaccatatggaagtttacgagactatcttcaaaaacataaagaacggata
gatcacaaaaaacttctgcagtacacatctcagatatgcaagggtatggagtatcttggt
acaaaaaggtatatccacagggatctggcaacaagaaatatattggtggagaatgagaac
agagttaaaattggagattttgggttaaccaaagtcttgccacaagacaaagaatactat
aaagtaaaagaacctggtgaaagtcccatattctggtatgccccagaatcactgacagag
agcaagttttctgtggcctcagatgtttggagctttggagtggttctgtatgaacttttc
acatacattgagaagagtaaaagtccaccagcggtcagtgtgcttttcatttactttcag
ttttttgtt

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