KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108523523
Entry
108523523         CDS       T04641                                 
Symbol
NOTCH2
Name
(RefSeq) LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2
  KO
K20994  Notch 2
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01522  Endocrine resistance
rbb04330  Notch signaling pathway
rbb04658  Th1 and Th2 cell differentiation
rbb04919  Thyroid hormone signaling pathway
rbb05165  Human papillomavirus infection
rbb05200  Pathways in cancer
rbb05206  MicroRNAs in cancer
rbb05207  Chemical carcinogenesis - receptor activation
rbb05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    108523523 (NOTCH2)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    108523523 (NOTCH2)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    108523523 (NOTCH2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108523523 (NOTCH2)
   05206 MicroRNAs in cancer
    108523523 (NOTCH2)
   05207 Chemical carcinogenesis - receptor activation
    108523523 (NOTCH2)
  09162 Cancer: specific types
   05224 Breast cancer
    108523523 (NOTCH2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    108523523 (NOTCH2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    108523523 (NOTCH2)
SSDB
Motif
Pfam: EGF hEGF EGF_TEN EGF_CA Ank_2 EGF_2 Ank NOD Notch NODP Ank_5 Ank_3 Ank_4 EGF_3 EGF_Teneurin JAG1-like_EGF2 Elf-1_N
Other DBs
NCBI-GeneID: 108523523
NCBI-ProteinID: XP_017719649
LinkDB
Position
Unknown
AA seq 2466 aa
MPALRPALLWALLALWLCRAAPARALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE
YCQHRDPCEKNRCQNGGTCVAQAMLGKAMCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT
CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG
DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM
DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ
VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN
PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP
PGFSGMDCEEDIDDCLANPCQNGGSCVDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN
GGTCSDYVNSYTCKCQAGFDGVHCENNIDECTESSCFNGGTCVDGINSFSCLCPVGFTGL
FCLHEINECSSHPCLNEGTCVDGLGTYHCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCIQ
DKAESRCRCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCIDAGNTHYCQCPLG
YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCVDRIGGYSCRCLPGFAGER
CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA
VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPNPRDCESGCAS
SPCQHGGSCHPQRQPPYYSCQCAPPFWGSRCELYTAPPSTPPATCLSQYCADKARDGVCD
EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTAECLFDNFECQGNS
KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQ
DARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSIPGEQEQEVAG
SKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLY
LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNRKRREPVGQDAVGLKNL
SVQVSEANLIGSGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIR
RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIIT
DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTY
VSDTTSSPMITSPGMLQASPNPMLATAAPPASVHAQHALSFSNLHEMQPLAHGASTVLPS
VSQLLSHHHIVPPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHP
SIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVTGPLPTMY
QLPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAADE
HQSQCHLQGSIPTPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMSEPPHN
NMQVYA
NT seq 7401 nt   +upstreamnt  +downstreamnt
atgcccgccctgcgccccgctctgctgtgggcgctgctggcgctctggttgtgccgcgcg
gcccccgcgcgtgccttgcagtgtcgagatggctatgaaccctgtgtaaatgaaggaatg
tgtgttacctaccacaatggcacaggatactgcaaatgtccagagggcttcttgggagaa
tattgtcaacatcgagacccatgtgagaagaaccgctgccagaatggtgggacttgtgtg
gcccaggccatgctggggaaagccatgtgccgatgtgcctcagggttcacgggagaggac
tgccagtattcgacatctcacccatgctttgtgtctcgcccgtgcctgaatggtggcaca
tgccatatgctcagccgggatacctatgagtgcacctgccaagttgggtttacaggtaag
gagtgccaatggactgatgcctgcctgtctcatccctgtgcaaatggaagtacctgtacc
actgtggccaatcagttctcctgcaaatgcctcacaggcttcacagggcaaaagtgtgag
actgatgtcaatgagtgtgacattccaggacactgccagcatggtggcacctgcctcaac
ctgcctggttcctatcagtgccagtgccctcagggcttcacaggccagtactgtgacagc
ttgtatgtgccctgtgcaccctcgccttgtgtcaatggaggcacctgtcggcagactggt
gacttcacttttgagtgcaactgtcttccaggttttgaagggagcacctgtgagaggaat
attgatgactgccctaaccacaggtgtcagaatggaggggtttgtgtggatggggtcaac
acttacaactgccgctgccccccacaatggacaggacagttctgcacagaggatgtggat
gaatgcctgctgcagcccaatgcctgtcagaatgggggcacctgtgccaaccgcaatgga
ggctatggctgtgtgtgtgtcaacggctggagtggagatgactgcagtgagaacattgat
gattgtgccttcgcctcctgtactccaggctccacctgcatcgaccgtgtggcctccttc
tcttgcatgtgcccagaggggaaggcaggtctcctgtgtcatctggatgatgcatgcatc
agcaatccttgccacaagggggcactgtgtgacaccaaccccctaaatgggcagtatatt
tgcacctgcccccaaggctacaaaggggctgactgcacagaagatgtggatgagtgtgcc
atggccaatagcaatccttgtgagcatgcaggaaaatgtgtgaacacagatggcgccttc
cactgtgagtgtctgaaaggttatgcaggacctcgttgtgagatggacatcaatgagtgc
cattcagatccctgccagaatgatgctacctgtctggataagattggaggcttcacatgt
ctgtgcatgccaggtttcaaaggtgtgcattgtgaattagaaataaatgaatgtcagagc
aacccttgtgtgaacaatgggcagtgtgtggataaagtcaatcgtttccagtgcctgtgt
cctcctggttttactgggccagtttgccagattgatattgatgactgttccagtactccg
tgtctgaatggggcaaagtgtatcgatcacccgaatggctatgaatgccagtgtgccaca
ggtttcactggtgtgttgtgtgaggagaacattgacaactgtgaccccgatccttgccac
catggtcagtgtcaggatggtattgattcctacacctgcatctgcaatcctgggtacatg
ggcgccatctgcagtgaccagattgatgaatgttatagcagcccttgcctgaacgatggt
cgctgcatcgacctggtcaatggctaccagtgcaactgccagccgggcacatcaggagtt
aattgtgaaattaattttgatgactgcgcaagtaacccttgtatccatggaatctgtatg
gatggcattaatcgctacagttgtgtctgctcaccaggattcacagggcagagatgtaac
attgacatcgatgagtgtgcctccaatccctgtcgcaagggtgcaacatgtatcaacggt
gtgaatggtttccgctgtatatgccctgaggggccccatcaccccagctgctactcacag
gtgaacgaatgcctgagtaatccctgcatccatggaaactgtactggaggtctcagtgga
tataagtgcctctgtgatgcaggctgggttggcatcaactgtgaagtggacaaaaatgaa
tgcctttctaatccatgccagaatggaggaacttgtgacaatctggtgaatggatacagg
tgtacttgcaagaagggctttaaaggctataactgccaggtgaatattgatgaatgtgcc
tcaaatccttgcttgaaccaaggaacctgctttgatgacataagtggctacacttgccac
tgtgtgctgccatatacaggcaagaactgtcagacagtattggctccctgttccccaaac
ccttgtgagaatgctgctgtttgcaaagagtcaccaaattttgagagttacacctgcttg
tgtgctcctggctggcaaggtcagaggtgtaccattgacattgacgagtgtatctccaag
ccctgcatgaaccatggtctctgccataacacccagggcagctacatgtgtgaatgtcca
ccaggcttcagcggtatggactgtgaggaggacatcgatgactgccttgccaatccttgc
cagaatggaggttcctgtgtggatggagtgaatactttctcctgcctctgccttccgggt
ttcactggggacaagtgccagacagacatgaatgagtgtctaagtgaaccctgtaagaat
ggagggacctgctctgactacgtcaacagttacacttgcaagtgccaggcaggatttgat
ggagtccattgtgagaacaacatcgatgagtgcactgagagctcctgtttcaatggtggc
acatgtgttgatgggattaactccttctcttgcttgtgccctgtgggtttcactggactc
ttctgcctccatgagatcaatgaatgcagctctcatccatgcctgaatgagggaacgtgt
gttgatggcctgggtacctaccactgtagctgccccctgggctacactgggaaaaactgt
cagaccctggtgaacctctgcagtcggtctccatgtaaaaacaaaggtacttgcattcag
gataaagcagagtcccggtgccgatgtccatctggatgggctggtgcttattgtgacgtg
cccaatgtctcttgtgacatagcagcctccaggagaggtgtgcttgttgaacacttgtgc
cagcactcaggtgtctgcatcgatgctggcaacacacattactgtcagtgccccctgggc
tatactgggagctactgtgaggaacagctcgatgagtgtgcgtccaacccctgccagcac
ggggcaacgtgcagtgacttcattggtggatacagatgcgagtgtgtcccaggctatcag
ggtgtcaattgtgagtatgaagtggatgagtgccagaatcagccctgccagaatggaggc
acctgtattgaccttgtgaaccatttcaagtgctcctgcccaccaggcactcggggccta
ctctgtgaagagaacattgatgactgtgccaggggtccgcattgccttaatggtggtcag
tgcgtggataggattggaggctacagttgtcgctgcttgcctggctttgctggggagcga
tgtgagggagacatcaatgagtgcctctccaacccctgcagctctgagggcagtctggac
tgtatacagctcaccaatgactacctgtgtgtttgccgtagtgcctttactggccggcac
tgtgaaactttcgtcgatgtgtgtcctcagatgccctgcctgaatggagggacttgtgct
gtggccagtaacatgcctgatggtttcatttgccgttgtcccccgggattttccggggca
aggtgccagagcagctgtggacaagtgaaatgtaggaaaggggagcaatgtgtgcacacc
gcctctggaccccgctgcttttgccccaacccccgggactgcgagtcaggctgtgccagt
agcccctgccagcacggaggcagctgccaccctcagcgccagcctccttattactcctgc
cagtgtgccccaccattctggggtagccgctgtgaactctacacggcaccccccagcacc
cctcctgccacctgtttgagccaatattgtgctgacaaagctcgtgatggcgtctgtgat
gaggcctgcaacagccatgcctgccagtgggatgggggtgactgttctctcaccatggag
aacccctgggccaactgctcctccccacttccctgctgggattatatcaacaaccagtgt
gatgagctgtgcaacacggccgagtgcctgtttgacaactttgaatgccaggggaacagc
aagacatgcaagtatgacaaatactgtgcagaccacttcaaagacaaccactgtgaccag
gggtgcaacagtgaggagtgtggttgggatgggctggactgtgctgctgaccagcctgag
aacctggcagagggtaccctggttattgtggtattgatgccacctgaacagctgctccag
gatgctcgcagcttcttgcgggcactggggaccctgctccacaccaacctgcgcattaag
agggactcccagggggagctcatggtgtacccctattatggtgagaagtcagctgccatg
aagaaacagaggatgacacgcaggtccattcctggtgaacaagagcaggaggtggctggc
tctaaagtctttctggaaattgacaaccgccagtgtgttcaagactcagatcactgtttc
aagaacacagatgcagcagcagctctcctggcctctcacgccatacaggggaccctgtca
taccctctcgtgtctgtcgtcagtgaatccctgactccagaacgcactcagctcctctat
ctccttgctgttgctgttgtcatcattctgtttattattctgctgggggtaatcatggca
aaacgaaagcgtaagcatggctctctctggctgcctgaaggtttcactcttcgccgagat
gcaagcaatcgcaagcgtcgtgagccagtgggacaggatgctgtggggctgaaaaatctc
tcagtgcaagtctcagaagctaacctaattggttctggaacaagtgaacactgggtcgat
gatgaagggccccaaccaaagaaagtgaaggctgaagatgaagccttactctcagaagaa
gacgaccccattgatcgacggccatggacacagcagcaccttgaagccgcagacatccgt
aggacaccatcactggccctcacccctcctcaggcagagcaggaggtggatgtgttggat
gtgaatgtccggggcccagatggctgcaccccattaatgttggcttctctccgaggaggc
agctcagatttgagtgatgaagatgaagatgcagaggactcttctgctaacatcatcaca
gacttggtctaccaaggtgccagcctccaggcccagacggaccggactggtgagatggcc
ctgcaccttgcagcccgctactcacgggctgatgctgccaagcgtctcctggatgcaggt
gcagatgccaatgcccaggacaacatgggccgctgccccctccatgctgcagtggcagct
gatgcccaaggtgtcttccagattctgattcgcaaccgagtaactgatctagatgccagg
atgaatgatggtactacacccctgatcctggctgcccgcctggctgtggagggaatggtg
gcagaactgatcaactgccaagcagatgtgaatgcagtggatgaccatggaaaatctgct
cttcactgggcagctgctgtcaataatgtggaggcgactcttttgctgttgaaaaatggg
gctaaccgagacatgcaggacaacaaggaagagacacctctgtttcttgctgcccgggag
gggagctatgaagcagccaagatcctgttagaccattttgccaatcgagacatcacagac
catatggatcgtcttccccgggatgtggctcgagatcgcatgcaccatgacattgtgcgc
ctcctggatgaatacaatgtgaccccaagccctccaggcactgtgttgacttctgctctc
tcacctgtcatctgtgggcccaacagatctttcctcagcctgaagcacaccccaatgggc
aagaagtctagacggcccagtgccaagagtaccatgcccactagcctccctaaccttgcc
aaggaggcgaaggatgccaagggtagtaggaggaagaagtctctgagtgagaaggtccaa
ctgtctgagagttcagtaactttatctcctgttgattccctagaatctcctcacacatac
gtttccgataccacatcctctccaatgattacatcccctgggatgttacaggcctcaccc
aaccctatgttggccactgccgcccctcctgcctcagttcatgcccagcatgcactgtct
ttttctaaccttcatgaaatgcagcctttggctcatggggccagcactgtgcttccctca
gtgagccagttgctatcccaccaccacattgtgcccccaggcagtggcagtgctggaagc
ttgagtaggctccatccagtcccagtcccagcagattggatgaaccgcatggaggtgaat
gaaacccagtacaatgagatgtttggcatggtcctggctccagctgagggcacccaccct
agcatagctccccagagcaggccacctgaagggaagcacataaccacccctcgggagccc
ttgccccccattgtgactttccagctcatccctaaaggcagtattgcccaaccagcaggg
gctccccagcctcagtccacctgccctccagctgttacaggccccctgcccaccatgtac
cagcttccagaaatggcccgtttgcccagtgtggccttccccactgccatgatgccccaa
caggacgggcaggtagctcagaccattctcccagcctatcatcctttcccagcctctgtg
ggaaagtaccccacacccccttcacagcacagttatgcttcctcaaatgctgctgacgaa
caccagtcacagtgtcacctccaggggagcatccctaccccagagtctcctgaccagtgg
tcaagttcatcaccccactctgcttctgactggtcagatgtgaccaccagccctacccct
gggggtgctggaggaggtcagcggggacctgggacacacatgtctgagccaccacacaac
aacatgcaggtttatgcgtga

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