Rhinopithecus bieti (black snub-nosed monkey): 108527976
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Entry
108527976 CDS
T04641
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00230
Purine metabolism
rbb01100
Metabolic pathways
rbb04024
cAMP signaling pathway
rbb05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
108527976 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
108527976 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
108527976 (PDE10A)
Enzymes [BR:
rbb01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
108527976 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
108527976 (PDE10A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
108527976
NCBI-ProteinID:
XP_017725034
LinkDB
All DBs
Position
Unknown
AA seq
806 aa
AA seq
DB search
MLKSGSKGPALLTLRSGTDPRAQMSDDTAEGTLDPCSAPGLTDEKVKAYLSLHPQVLDEF
VSESVSAETVEKWLKRKNNKSEDESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQ
LLLYELSSIIKIATKADGFALYFLGECNNSLCIFTPPGIKEGKPRLIPAGPITQGTTISA
YVAKSRKTLLVEDILGDERFPKGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKE
AFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEH
IMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQ
VARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAF
SKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTAEEWQDLMRFT
LPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVP
YHNWKHAVTVAHCMYAILQNNHALFTDLERKGLLIACLCHDLDHRGFSNTYLQKFDHPLA
ALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRK
QLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEM
KKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWE
KVIRGEETATWISSPSVAQKAAASED
NT seq
2421 nt
NT seq
+upstream
nt +downstream
nt
atgcttaaaagtgggagcaaaggacccgctttgttgactttgaggagcgggacagacccc
cgggcacagatgagcgatgacacagcagaaggcaccctggacccctgcagtgcgccaggt
ttgacagatgaaaaagtgaaggcatatctttctcttcacccccaggtattagatgaattt
gtatctgaaagtgttagtgcagagacagtagagaaatggctgaagaggaagaacaacaaa
tcagaagatgaatcggctcctaaggaagtcagcaggtaccaagatacgaatatgcaggga
gttgtatatgaactaaacagctatatagaacaacggttggacacaggaggagacaaccag
ctactcctctatgaactgagcagcatcatcaaaatagccacaaaagctgatggatttgca
ttgtatttccttggagagtgcaataatagcctgtgcatattcacaccacctgggataaag
gaaggaaaaccccgcctcatccctgctgggcccattactcagggcaccaccatctctgct
tatgtggccaagtccaggaaaacattgctagtagaagacatccttggagatgaacgattt
ccaaaaggtactggactggaatcagggactcgtatccagtctgttctttgcttaccgatt
gtcactgcaattggtgacttgattggtattcttgagctgtatcggcactggggcaaagaa
gccttctgtcttagtcaccaggaggttgcaacagcaaatcttgcctgggcttcagtagca
atacatcaggtgcaggtatgcagaggccttgccaaacagactgaattgaatgactttcta
ctcgacgtatcaaaaacatattttgataacatagttgcaatagattctctacttgaacac
ataatgatatatgcaaaaaacctggtgaatgccgaccgttgtgcacttttccaggtagac
cataagaacaaggagttatattcagacctttttgatatcggagaggaaaaggaaggaaaa
cctgtcttcaagaagaccaaagagataagattttcaattgagaaaggaattgctggccaa
gtagcaagaacaggggaagtcctgaacattccagatgcctatgcagacccacgctttaac
agagaagtagacttgtacacaggctacaccacgcggaatatcctgtgcatgcccatcgtc
agccgaggcagcgtgataggtgtggtgcagatggtcaacaaaatcagtggcagtgccttc
tctaaaaccgatgaaaataacttcaaaatgtttgccgtcttttgtgctttagccttacac
tgtgctaatatgtatcatagaattcgccactcagagtgcatttaccgggtaacgatggaa
aagctgtcctaccatagcatttgtactgcagaagagtggcaagacctcatgcgattcacc
cttcctgtgcgtctctgcaaagaaattgaattattccactttgacattggtccttttgaa
aacatgtggcctggaatttttgtctacatggttcatcggtcctgtgggacatcctgcttt
gagctcgaaaagttgtgtcgttttattatgtctgtgaagaagaactatcggcgggttcct
tatcacaactggaagcatgcggtcactgtagcccactgcatgtacgccatacttcagaac
aatcacgcgcttttcacagaccttgagcgcaaaggattgctgattgcgtgtctgtgtcat
gacctagaccacaggggctttagtaacacctacctgcagaagttcgaccaccctctagca
gctctctactccacttccaccatggaacagcaccacttctcccagaccgtgtccatcctc
cagttggaagggcacaatatcttctccactctgagctccagtgaatacgagcaggtgctt
gagatcatccgcaaagccatcattgccacagaccttgctttatactttggaaacaggaaa
cagttggaagagatgtaccagaccggatcgctaaaccttaataatcaatcacatagagac
cgtgtaattggtttgatgatgacggcctgtgacctttgttctgtgacaaaactgtggccc
gttacaaaattgacggcaaatgatatatatgcagaattctgggctgagggtgatgaaatg
aagaaattgggaatacagcctattcctatgatggacagagacaagaaggatgaagtcccc
caaggccagcttgggttctacaatgccgtagccattccctgctacacaacccttacccag
atcctccctcccacggagcctctccttaaagcatgcagggataatctcaatcagtgggag
aaggtgattcgaggagaggagactgcaacctggatttcatccccatccgtggctcagaag
gcagctgcatctgaagactga
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