Rhinopithecus bieti (black snub-nosed monkey): 108528604
Help
Entry
108528604 CDS
T04641
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04270
Vascular smooth muscle contraction
rbb04360
Axon guidance
rbb04611
Platelet activation
rbb04625
C-type lectin receptor signaling pathway
rbb04810
Regulation of actin cytoskeleton
rbb05135
Yersinia infection
rbb05152
Tuberculosis
rbb05163
Human cytomegalovirus infection
rbb05200
Pathways in cancer
rbb05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
108528604 (ARHGEF12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
108528604 (ARHGEF12)
04625 C-type lectin receptor signaling pathway
108528604 (ARHGEF12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
108528604 (ARHGEF12)
09158 Development and regeneration
04360 Axon guidance
108528604 (ARHGEF12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108528604 (ARHGEF12)
05205 Proteoglycans in cancer
108528604 (ARHGEF12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
108528604 (ARHGEF12)
09171 Infectious disease: bacterial
05135 Yersinia infection
108528604 (ARHGEF12)
05152 Tuberculosis
108528604 (ARHGEF12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rbb04131
]
108528604 (ARHGEF12)
Membrane trafficking [BR:
rbb04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
108528604 (ARHGEF12)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PH_13
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
AAA_23
Motif
Other DBs
NCBI-GeneID:
108528604
NCBI-ProteinID:
XP_017725967
LinkDB
All DBs
Position
Unknown
AA seq
1544 aa
AA seq
DB search
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVVIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIRSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVVIPSRPLGDTLTVSEAETDPGDGLGRTDCSSGDAS
RPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR
VFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKVRQSGLANEGTDAGY
LPANSMSSVASGASFSQEGGKENDTGSKQVGETPAPGDTLDGTPRTLNTVFDFPPPPLDQ
VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIGKYTEWPTEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK
PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTS
GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQITIPDSHLPVSEERWALDALRNLGLLK
QLLVQQLGLTEKSAQEDWRHCPRYRTASQGLQTDSVIQNSENIKAYHSGEGHRPFRTGTG
DIATCYSPRTSTESSAPRDSVGLAPQDSQASNILVMDHMMMTPEMPTMEPEGGLDDSGEH
FFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ
PMTGIPAMESTHQQQHSPQNTHSDGAVSPFTPEFLVQQRWGAMEDSCFEIQSPSSCADSQ
SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS
NT seq
4635 nt
NT seq
+upstream
nt +downstream
nt
atgagtggcacacagtctactatcaccgacaggtttcccctcaaaaaacctattaggcat
ggaagtattttgaaccgagagtcaccaacagataagaagcagaaagttgagcgcattgca
tcacatgattttgaccccacagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatatatggtcttgttcaacgttgcgtagtcatccagaaagatgacaat
ggatttgggctgacggtcagtggagacaatccagtcttcgtacagtctgtcaaagaagat
ggagcagccatgcgggctggagtacagacaggtgatcgaatcatcaaggtgaatggaact
ctggtgactcattcaaatcatctggaggtggtgaagctaatcagatctggttcctatgta
gctctcactgttcagggacgcccacctgggtcgccccagattccacttgccgactctgaa
gtagagccatcagtcattggacatatgtctcccatcatgacatctcctcattcacctgga
gcatctgggaatatggaaagaatcactagtcctgtgctcatgggggaggaaaacaatgtg
gttcataaccagaaagtagaaattctgagaaaaatgttacagaaagaacaggaacggcta
cagttattgcaggaagattacaaccgaacacctgcccaaagattgctaaaagagatccaa
gaggccaagaaacacattcctcagctgcaagagcagttatccaaagccacaggctctgct
caggatggagctgtagttataccctccagacctttaggtgacaccctaacagtcagtgag
gcagaaacagatcctggagatggcctgggcaggactgactgtagcagtggagatgcttct
cggcccagtagtgacaatgcagatagtcccaagagtggcccaaaagagaggatttatcta
gaggaaaacccagagaaaagtgaaacaattcaggacactgacactcaatcacttgtcggg
agtccctcaacccgtatagcacctcatattattggagcagaagatgatgattttggtact
gaacatgaacagatcaatggacagtgcagctgtttccagagcattgaattactaaaatct
cgcccggctcatttggctgttttcttacaccatgtagtttcacaatttgaccctgcaact
ttgctttgttatctctattcagacctgtataaacataccaattccaaggaaactcgtcgc
gtcttccttgagtttcatcagttctttctagatcgatcagcacacctgaaagtttctgtt
cctgatgaaatgtctgcagatctagaaaagagaagacctgagctcattcctgaggatctg
catcgccactatatccaaactatgcaagaacgagtccatccagaagttcaaaggcactta
gaagattttcggcagaaacgtagtatgggactgaccttggctgaaagcgagctgactaaa
cttgatgcagagcgagacaaggaccggttgactttggagaaggagcggacatgtgcagaa
cagattgttgccaaaattgaagaagtattgatgactgctcaggctgtagaggaagataag
agttccaccatgcagtatgttattctcatgtatatgaagcatttgggagtaaaagtgaaa
gagcctcgaaatttggagcacaaacggggtcggattggatttcttcccaaaatcaagcaa
agtatgaagaaagataaagaaggggaagaaaaagggaagcgaagaggattccccagcatc
ctgggacccccacggagaccaagccgtcatgacaacagtgcaattggcagagccatggaa
ctacagaaggcgcgccaccctaagcacttatccacaccctcatctgtgagtcctgaacct
caggactctgccaaggtgcgccagagtgggttagcaaatgaaggaacagacgctggatac
ctgcctgccaattccatgtcttctgtagcttcaggggcctctttttcccaggaaggaggg
aaagagaatgatacaggatcaaagcaagttggagaaacaccagcacctggagacacctta
gatggcacacctcgtactctcaatactgtctttgatttcccaccacctccattagaccaa
gtgcaggaggaggaatgtgaagtagaaagggtgactgaacatgggacaccaaagcccttt
cgaaagtttgacagtgtagcttttggagaaagtcaaagtgaggatgaacaatttgaaaac
gacttagagacagatccacccaactggcagcagcttgttagtcgagaagtgttattggga
ctaaaaccttgtgagattaaaagacaggaagtgattaatgaattgttctacactgaaaga
gctcatgttcgaacactgaaggttcttgatcaagtgttctatcagcgagtgtccagagaa
ggaattctgtcaccctcagagctacggaaaattttttcaaacttggaagatattcttcaa
cttcatattggattgaatgaacaaatgaaggctgttcgaaagagaaatgagacctctgtt
atcgatcagattggggaagatttgctgacatggttcagcggaccaggagaggagaaattg
aaacatgctgctgctaccttttgcagtaaccagcctttcgccctggaaatgatcaagtct
cgtcagaaaaaggattctcgatttcagacttttgtgcaagatgctgaaagtaatccactg
tgtcgacgtcttcaactgaaggatattattcccactcaaatgcaaaggcttactaagtac
ccgcttctattggataatattggcaaatacacagaatggccaacagaaagggaaaaggtg
aagaaagctgcagatcactgtcgtcagatcttaaattatgtaaatcaggctgtcaaggag
gcagaaaacaagcagcgcctcgaagattatcagcgtcgccttgatacctccagcctgaag
ttgtcagagtacccaaatgttgaagagctcaggaatttggatttaacaaaaaggaagatg
attcatgaagggccattggtttggaaggtgaatagagataaaactattgatttatacaca
ttgctgctggaagacattcttgtattgttacaaaagcaggatgatagactggtgttaagg
tgtcatagtaagattctggcatctacagctgatagcaaacatacgtttagccctgtcatt
aagttgagtacagtgttggttcgacaagtggcaacagataacaaagctttattcgtcatc
tccatgtcagacaatggagctcagatttatgaactggtggcacagacagtttctgaaaag
actgtctggcaggacctaatctgtcggatggctgcatcagtgaaggagcaatccacaaag
ccaattccattaccccagtcaacacctggcgaaggagataatgatgaagaagatccttca
aaattaaaagaggaacagcatggcatttcagtcactggtttgcagagtccagacagagat
ttgggattagaatctaccttaatatcatcaaaacctcagtctcattcactgagtacctct
gggaaatcagaggtacgtgatctctttgtggctgagagacagtttgcaaaggaacaacat
acagatgggacactaaaggaagttggagaagattatcaaatcacaatcccagattcacac
ctgcctgtctcagaagaacggtgggcattggatgcactaagaaatttgggtttgttgaag
cagttgctggtgcagcagctcggtttgactgagaagagcgctcaggaagactggcgacat
tgcccaagatataggacagcctctcaggggctgcagacagacagtgtcatccagaactct
gaaaatattaaggcctatcattctggtgaaggacataggccctttagaactggaactggt
gacattgcaacttgttacagtccacggacttcaactgaatcttctgctccacgggattca
gtgggactggcaccccaggatagccaggcaagtaacattttagtaatggaccacatgatg
atgaccccagagatgcctaccatggagccagaagggggtcttgatgacagtggagagcac
ttttttgatgcccgtgaagcacatagtgatgagaatccatcagaaggtgatggagcagtt
aacaaggaagagaaggatgttaatttacgcatctcaggaaactatttgatccttgatggc
tatgacccagtgcaggagagttccacagatgaggaagttgcttcctcacttaccctgcag
cccatgacaggcatccctgctatggaatccacccaccagcagcaacattctcctcagaac
actcactccgatggggcagtttcaccattcacccccgaatttctggtccagcagcgctgg
ggagctatggaggattcctgttttgagatccagagtccctcctcttgtgcagattcgcag
agccagatcatggagtacattcataagatagaggctgaccttgaacacttaaagaaggtg
gaggaaagttacaccattctttgccaaaggctggctggatcagccctcacagacaagcac
tcagataaaagttag
DBGET
integrated database retrieval system
