Rhinopithecus bieti (black snub-nosed monkey): 108530203
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Entry
108530203 CDS
T04641
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate---cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00270
Cysteine and methionine metabolism
rbb00480
Glutathione metabolism
rbb01100
Metabolic pathways
rbb01240
Biosynthesis of cofactors
rbb04216
Ferroptosis
Module
rbb_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
108530203 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
108530203 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
108530203 (GCLC)
Enzymes [BR:
rbb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
108530203 (GCLC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
108530203
NCBI-ProteinID:
XP_017728412
UniProt:
A0A2K6LLS6
LinkDB
All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EANMRKRRKEATSILEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEASRASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNSNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKAAQKRDAVL
QGMFYFRKDICKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LILKCNQIANELCECPELLGSAFRKVKYGGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggaaaccaagcgccatgccgac
cacgtgcggcggcacgggatcctccagttcctacacatctaccacgccgtcaaggaccgg
cacaaggacgttctcaagtggggcgatgaggtggaatacatgttggtatcttttgatcat
gaaaataaaaaagtccggttggtcctgtctggggagaaagttcttgaaactctacaagag
aagggggaaaggacaaacccaaaccatcccaccctttggagaccagagtatgggagttac
atgattgaagggacaccgggacagccctacggaggaacgatgtccgagttcaacacagtt
gaggccaacatgcgaaaacgccggaaggaggctacttctatattagaagaaaatcaggct
ctttgcacaataacttcatttcccagattaggctgtcctgggttcacactgcccgaggtc
aaacctaacccagtggaaggaggagcttccaagtccctcttctttccagatgaagcaata
aacaagcaccctcgcttcagtaccttaacaagaaatatccgacataggagaggagaaaag
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccatttatagaaaca
tttcctgaggatgatgaagcttcaagggcttctaagccagatcatatttacatggatgcc
atgggatttggaatgggcaattgctgtcttcaggtgacattccaagcctgcagtatatct
gaggccagatacctttatgatcagttggctactatctgtccaattgttatggctttgagt
gctgcatctcccttttaccgaggctatgtgtcagacatcgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccattgaagaacagt
aactataggatcagtaaatcccgatatgactcaatagacagctatttatctaagtgtggt
gagaaatataatgacatcgacttgacgatagataaagagatctacgaacagctgttgcag
gaaggcattgatcatctcctggcccagcatgttgctcatctctttattagagacccactg
acactgtttgaagagaaaatacacctggatgatgctaatgagtctgaccattttgagaat
attcagtccacaaattggcagacaatgagatttaagccccctcctccaaactcagatatc
ggatggagagtagaatttcgacccatggaggtgcaattaacagactttgagaactctgcc
tatgtggtgtttgtggtactgctcaccagagtgatcctttcctacaaattggattttctc
attccactgtcaaaggttgatgagaacatgaaggcagcacagaaacgagatgctgtcttg
cagggaatgttttatttcaggaaagatatttgcaaaggtggcaacgcagtggtggatggt
tgtggcaaggcccagaacagcacagagcttgctgcagaggagtacaccctcatgagcata
gacaccatcatcaatgggaaggaaggtgtgtttcctggactgatcccaattctgaactct
taccttgaaaacatggaagtggatgtggacaccagatgtagtattctgaactacctaaag
ctaattaagaagagagcatctggagaactaatgacagttgccagatggatgagggagttt
atcgcaaaccatcctgactacaagcaagacagtgtcataactgatgaaatgaattatagc
cttattttgaagtgtaaccaaattgcaaatgaattatgtgaatgcccagagttacttgga
tcagcatttaggaaagtaaaatatggtggaagtaaaactgactcatccaactag
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