Rhinopithecus bieti (black snub-nosed monkey): 108531435
Help
Entry
108531435 CDS
T04641
Symbol
DOT1L
Name
(RefSeq) LOW QUALITY PROTEIN: histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00310
Lysine degradation
rbb01100
Metabolic pathways
rbb05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
108531435 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
108531435 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
rbb03036
]
108531435 (DOT1L)
Enzymes [BR:
rbb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
108531435 (DOT1L)
Chromosome and associated proteins [BR:
rbb03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
108531435 (DOT1L)
HMT complexes
Dot1-containing complex
108531435 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
108531435
NCBI-ProteinID:
XP_017730366
LinkDB
All DBs
Position
Unknown
AA seq
1732 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAATPTKGP
EGKLAGPTDAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTA
NPERKPKKNQTALDVLHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNTQLLGAAQQLLSHCQAQK
EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRSQSLQLL
KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDALSLHLRGKGALGRELEPDAGRLHLELDCAKFSLPHLSSMSPELSMNGQAAGY
ELCSALSRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLAAPDYTRLSPAKIV
LRRHLSQDHTVPSRPAASELHPRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQL
AGEKSSEKGLRERAYGSGGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARST
PSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGA
ELATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPL
TEASKGDLPSDSGFSDPESEAKRRIVFTIATGAGSAKQSPSSKHSPLTASARGDCVPSHG
QDSRKRGRRKRASTGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEI
TAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARI
ERKIATISLESKSPPKTLENGGGLAGRKPTPASEPVNNSKWKSTFSPISDIGLAKSADSP
LQASSALSQNSLFTFRPALEEPPADAKLATHPRKGFPSSLSGADGLSPSTNPANGCTFGG
GLAADLSLHSFSDGASLPHKGPEAASLSSPLSFPSQRGKEASDANPFLSKRQLDGLAGLK
GEGSRSKEAGEGGLQLCGPTDKTPLLTGKAAKARDRELDLKNGHNLFISAAAVPPGSLLS
GPGLAPVASSAGGAASSTQTHRPFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSS
VPAAAGLVHVSSAATRLTNSHAMGSFSGVAGSTVGGVFNHAVPSASAHPFGARVGRGAAC
GSATLGPSPLQAAASSFQAPASVETRPPPPPPPPPXAPPAHQGRPPAGPPVLHAPPPPNA
ALPPPPTLLASNPEPALLQSLASLPPNQAFLPPTSAASLPPANASLSIKLTSLPHKGARP
SFTVHHQPLPRLALAQAAPGIPQASATGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5199 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgagactcaagtcgcccgtgggggctgagcccgccgtctac
ccgtggccgttgccggtctacgacaaacatcacgatgctgctcatgaaatcatcgagacc
atccgatgggtgtgtgaagaaatcccggatctcaagctcgctatggagaattacgtttta
attgactatgacaccaaaagcttcgagagcatgcagaggctctgcgacaagtacaaccgc
gccatcgatagcatccaccagctgtggaagggcaccacgcagcccatgaagctgaacacg
cggccgtccaccgggctcctgcgccatatcctgcagcaggtctacaaccactcggtgact
gaccccgagaagctcaacaactacgagcccttctccccggaggtgtacggggagacctcc
ttcgacctggtggcccaaatgatcgacgagatcaagatgaccgacgacgacctgtttgtg
gacttggggagcggtgtgggccaggtcgtgctccaggttgccgctgccaccaactgcaaa
catcactatggcgtcgagaaagcagacatcccggccaagtatgcggagaccatggaccgc
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacattggagaga
ggcgatttcctctcagaagagtggagggagcggattgccaacacgagtgttatatttgtg
aataattttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatg
aaggaaggtggcagaatcgtgtcctcgaaaccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtggtggagctgtcgcccctgaag
ggctcggtgtcgtggacagggaagccagtctcctactacctgcacactatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaacccaaaactcagggaggaacaggaggca
gcccggcgccgccagcagcgcgagagcaagagcaacgcggccacgcccaccaagggcccc
gagggcaagctggccggccccactgacgcccccatggactctggtgctgaggaagagaag
gcaggagcagccaccgtgaagaagccgtctccctccaaagcccgcaagaagaagctcaac
aagaaggggaggaagatggctggccgcaagcgcgggcgccccaagaagatgagcactgcg
aaccccgagcggaagcccaagaagaaccaaactgcactggatgtcctgcacgctcagacc
gtgtctcagacggcagcctcctcgccccaggatgcctacaggtcccctcacagcccgttc
taccagctacctccgagcgtgcagcggcactcccccaacccgctgctggtggcgcccacc
ccgcccgcgttgcagaagctgctagagtctttcaagatccagtacctgcagttcctggca
tacacaaagaccccccagtacaaggccagcctacaggagctgctgggccaggagaaggag
aagaacacccagctcctgggcgcggctcagcagctcctcagccactgccaggcccagaag
gaggagatcaggaggctgttccagcaaaaattggatgagctgggcgtgaaggcgctgacc
tacaacgacctgattcaggcgcagaaggagatctccgcccacaaccagcagctgcgggag
cagtcggagcagctggagcaggacaaccgtgcgctgcgcagccagagcttgcagctgctc
aaggctcgctgtgaggagctgcagctagactgggccacgctgtccctggagaagctgctg
aaggagaagcaggccctgaagagccagatctcggagaagcagaggcactgcctggagctg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagctcctgcagctcaag
tcctgtgtgccgcctgatgacgccctgtctctgcacctacgcgggaagggtgctctgggc
cgcgagctggagcctgacgccggccggctgcacctggagctggactgcgccaagttctcg
ctgcctcacttgagcagcatgagcccagagctctccatgaacggccaggctgccggctat
gagctctgcagtgcgctgagccggccgtcatccaagcagaacacaccccagtacctggcc
tcacccctagaccaggaggtggtgccctgcacccccagccacagcggccggccacgcctg
gagaagctgtctggcctggctgcacccgactacaccaggctgtccccggccaagattgtg
ctgaggcggcacctgagccaggaccacacggtgcccagcaggccggccgccagtgagctg
cacccaagagctgagcacaccaaggagaacggccttccctaccagagccccagcgtgcct
ggcagcatgaagctgagtccccaggacccgcggcccctgtcacctggggccttgcagctt
gctggagagaagagcagtgagaagggcctgagagagcgcgcctatggcagcggcggggag
ctcatcaccagcctgcccatcagcatcccgctcagcaccgtgcagcccaacaagctcccg
gtcagcatccccctggccagcgtggtgctgcccagccgcgctgagagggcgaggagcacc
cccagtcctgtgctgcagccccgcgacccctcatccacacttgaaaagcagattggtgct
aatgcccacggtgctgggagcagaagccttgccctggcccccgcaggcttctcctatgct
ggctctgtggccatcagcggggccttggcgggcagcccggcctctctcacacctggagcc
gagctggccaccttggatgagtcctccagctctgggagcctttttgccactgtggggtcc
cgcagctccacaccacagcaccccctgctgctggcacagccccggaactcgctcccggcc
tctcccgcccaccagctctcctccagcccccggcttggtggggctgcccagggcccgctc
actgaggccagcaagggggacttgccctcagattccggtttctcagatcctgagagtgag
gccaagaggaggatcgtgttcaccatcgccactggtgcgggcagtgccaaacagtcgccc
tccagcaagcacagccccctgaccgccagcgcccgtggggactgtgtgccgagccacggg
caggacagccgcaagcgcgggcggcggaagcgagcatcgacggggacgcccagcttgagc
gcaggcgtgtcccccaagcgccgagccctgccgtccgtcgctggccttttcacacaacct
tcagggtctcccctcaacctcaactccatggtcagtaacatcaaccagcccctggagatt
acagccatctcgtcccccgagacctccctgaagagctcccctgtgccctaccaggaccac
gaccagccccccgtgctcaagaaggagcggcctctgagccagaccaatggggcacactac
tccccgctcacctcggacgaggagccaggctctgaggacgagcccagcagcgcccgaatt
gagagaaaaattgcaacaatctccttagaaagcaaatctcccccgaaaactttggaaaat
ggtggtggtttggcgggaaggaagcccacgcccgcgagcgagccagtcaacaacagcaag
tggaagtccactttctcgcccatctctgacattggcctggccaagtctgcagacagcccg
ctgcaggccagctctgccctcagccagaactccctgttcacgttccggcccgccctggag
gagccccctgccgatgccaagctggccacccaccccaggaaaggctttcccagctctctg
tcgggggctgacggactcagcccgagcaccaaccctgccaacggctgcacctttggcggg
ggcctggccgcggacctgagtttacacagcttcagcgatggtgcttcccttccccacaag
ggccccgaggcggccagcctgagctccccgctgagcttcccctcgcagcgtggcaaggag
gcctcggacgccaaccctttcctgagcaagaggcagctggatggcctggctgggctgaag
ggcgagggcagccgcagcaaggaggcaggggagggcggcctgcagctgtgcgggcccacg
gacaagaccccactgctgactggcaaggccgccaaggcccgagaccgcgagctcgacctc
aagaatggccacaacctcttcatctccgctgcggccgtgcctcccggaagcctcctcagc
ggccccggcctggccccggtggcgtcctccgcaggcggcgcggcgtcctccacccagacg
caccggcccttcttgggccccttcccgccgggaccgcagtttgcgctcggccccatgtcc
ctgcaggccaacctcggctccgtggccggctcctccgtgctgcagtcgctgttcagctct
gtgccggccgccgcaggcctggtgcacgtgtcgtccgctgccaccagactgaccaactcg
cacgccatgggcagcttttccggggtggcaggcagcacagttggaggtgtctttaaccac
gcggtgccttccgcctctgctcatccgtttggagcccgtgtcggccgcggggctgcatgt
ggcagtgccacgctgggcccgagcccgctgcaggcggcggcctcttcctttcaggccccg
gcctcggttgagacccggccgccccctccgcctccgcctcccccgnctgccccgcctgcg
caccagggccggccccccgcggggcctcccgtcctccacgccccgcctccacctaacgcc
gccttgcctcctcccccaacgctgctggcctctaaccctgagcccgcgcttctgcagagc
ctcgcgtccctcccgcctaaccaagctttcttgccccccacctctgctgcctctctgccg
cctgctaacgcctctttgtctatcaagctcacctccctcccgcacaagggcgctcgcccc
tccttcacggtgcaccaccagcccctgccccggctggccctggcccaggccgcgcccggg
atcccgcaggccagcgccacggggccgtccgcggtgtgggtgtccctcggcatgccgcct
ccctatgccgcgcacctttcgggggttaagccgcgataa
DBGET
integrated database retrieval system
