Rhinopithecus bieti (black snub-nosed monkey): 108534715
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Entry
108534715 CDS
T04641
Symbol
TOP2A
Name
(RefSeq) LOW QUALITY PROTEIN: DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
108534715 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
rbb03032
]
108534715 (TOP2A)
03036 Chromosome and associated proteins [BR:
rbb03036
]
108534715 (TOP2A)
Enzymes [BR:
rbb01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
108534715 (TOP2A)
DNA replication proteins [BR:
rbb03032
]
Eukaryotic type
DNA Topoisomerases
108534715 (TOP2A)
Chromosome and associated proteins [BR:
rbb03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
108534715 (TOP2A)
Centrosome formation proteins
Centriole proteins
108534715 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
108534715
NCBI-ProteinID:
XP_017735689
LinkDB
All DBs
Position
Unknown
AA seq
1533 aa
AA seq
DB search
MEVSPLQPVNENMQVNKIKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFSGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVCENH
MWXFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSENLSKLXAIGCGIVESILNWVKFK
AQVQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSADCTLILTEGDSAKTLAVSGLGVVGR
DKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMI
MTDQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEW
KSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQI
DDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSM
VDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGS
NNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLRFLYDDNQRVEP
EWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGT
IEELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYR
EYHTDTTVKFVVKMTEGKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDI
LRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLI
QRGYDSDPVKAWKEAQQKVPDEEENEESDTEKETEKSNSVTDSGPTFNYLLDMPLWYLTK
EKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQIGLPGKGG
KAKGKKTQMAEVLPSPRGQRVIPRITIEMKAEAEKKNKKKIKNENTEGSPQEDGMELEGL
KQRLEKKQKREPGTKTKKQTTLPFKPIKKGKKRNPWSDSESDRSSDESNFDVPPRETEPR
RAATKTKFTVDLDSDEDFSDFDEKTDDEDFVPSDASPPKTKTSPKLTNKDLKPQKSAMSD
LEADDAKDSVPLSSSPPATHFPNETEITNTVPXKNVTVKKTAAKSQSSTSTTGAKKRAAP
KGTKREPALNSGVSQKPDPAKTKIRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGESDDF
HMDFDSAVAPRAKSVRAKKPIKYLEESDEDDLF
NT seq
4602 nt
NT seq
+upstream
nt +downstream
nt
atggaagtgtcaccattgcagcctgtaaatgaaaatatgcaagtcaacaaaataaagaaa
aatgaagatgctaagaaaagactgtctattgaaagaatctatcaaaagaaaacacaattg
gaacatattttgctccgcccagacacctacattggttctgtggaattagtaacccagcaa
atgtgggtttacgatgaagatgttggcattaactatagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgagattctagttaatgctgcggacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacaattgatccggaaaataatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgaaaagatgtatgtcccagctctc
atatttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtgacaggt
ggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggatggataatatggggaga
gctggtgagatggaactcaagcccttcagtggagaagattatacatgtatcacctttcag
cctgatttgtctaagtttaaaatgcaaagcctggacaaagatattgttgcactaatggtg
agaagagcatatgatattgctggatccaccaaagatgtcaaagtctttcttaatggaaat
aaactgccagtaaaaggatttcgtagttatgtggacatgtatttgaaggacaagttggat
gaaactggtaacccattgaaagtaatacacgaacaagtgaaccacaggtgggaagtgtgt
ttaaccatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtatgtgaaaatcac
atgtggnattttgtaaatgccttaattgaaaacccaacctttgactctcagacaaaagaa
aacatgactttacaaccaaagagctttggatcaacatgccaattaagtgaaaatttatca
aagctgtaagcaattggctgtggtattgtagaaagcatactaaactgggtgaagtttaag
gcccaagtccagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaatt
cccaaacttgatgatgccaatgatgcagggggccgaaactccgctgattgtacgcttatc
ctgactgagggagactcagccaaaactttggctgtttcaggccttggcgtggttgggaga
gacaaatatggggttttccctctgagaggaaaaatactcaatgttcgagaagcttctcat
aagcagatcatggaaaatgctgagattaacaatatcatcaagattgtgggtcttcagtac
aagaaaaactatgaagatgaagattcactgaagactcttcgttatgggaagataatgatt
atgacagatcaggaccaagatggttcccacatcaaaggcttgctgattaattttatccat
cacaactggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtg
aaggtgtccaaaaacaagcaagaaatggcattttatagccttccggaatttgaagaatgg
aagagttctactccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggtacc
agcacatcaaaggaagctaaagaatattttgcagatatgaaaagacatcgtatccagttc
aaatattctggtcctgaagatgatgctgctatcagcctggcctttagcaaaaaacagata
gatgatcgaaaggaatggttaactaatttcatggaggatagaagacaacgaaagttactt
ggacttcctgaggattacttgtatggacaaactaccacatatctgacatataatgacttc
atcaacaaggaacttatcttgttctcaaattctgataacgagagatctatcccttctatg
gtggatggtttgaaaccaggtcagagaaaggttttgtttacttgctttaaacggaatgac
aagcgagaggtaaaggttgcccagttagctggatcagtggctgaaatgtcttcttatcat
catggtgagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagc
aataatctgaacctcttgcagcccattggtcagtttggtaccagactgcatggtggcaag
gattccgctagtccacgatacatcttcacaatgctcagctctttggctcggttgttattt
ccaccaaaagatgatcacacattgaggtttttatatgacgacaaccagcgtgttgagcct
gaatggtacattcctattattcccatggtgctgataaatggtgctgaaggaatcggtacc
gggtggtcctgcaaaatccccaactttgatgtgcgtgaagttgtaaataacatcaggcgt
ttgatggatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtact
attgaagaactggctccaaatcaatatgtgattagtggtgaagtagctattcttaattcc
acaaccattgaaatctcagagcttcccatcagaacatggacccagacatacaaagaacaa
gttctagaacccatgttgaatggcactgagaagacacctcctctcataacagactatagg
gaataccatacagataccactgtgaaatttgttgtgaagatgactgaaggaaaactggca
gaggcagagagagttggactacacaaagtcttcaaactccaaactagtctcacatgcaac
tctatggtgctttttgaccacgtaggctgtttaaagaaatatgacacggtgttggatatt
ctaagagatttttttgaactcagacttaaatattatggattaagaaaagaatggctccta
ggaatgcttggtgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaa
atagatggcaaaataatcattgaaaataagcctaagaaagaattaattaaagttctgatt
cagaggggatatgattcagatcctgtgaaggcctggaaagaagcccagcaaaaggttcca
gatgaagaagaaaatgaagagagtgacaccgaaaaggaaactgaaaagagtaactctgta
acagattctggaccaaccttcaactatcttcttgatatgcccctttggtatttaaccaag
gaaaagaaagatgaactctgcagactaagaaatgaaaaagaacaagagctggacacatta
aagagaaagagtccatcagatttgtggaaagaagacttggctacatttattgaagaactg
gaggctgttgaagccaaggaaaaacaagatgaacaaatcggacttcctgggaaagggggg
aaggccaaggggaaaaaaacacaaatggctgaagttttgccttctccacgtggtcaaaga
gtcattccacgaataaccatagaaatgaaagcagaggcagaaaagaaaaataaaaagaaa
attaagaatgaaaatactgaaggaagccctcaagaagatggtatggaactagaaggccta
aaacaaagattagaaaagaaacagaaaagagaaccaggtacaaagacaaagaaacaaact
acattgccatttaagccaatcaaaaaaggaaagaagagaaatccttggtctgattcagaa
tcagataggagcagtgacgaaagtaattttgatgtccctccacgagaaacagagccacga
agagcagcaacaaaaaccaaattcacagtggatttggattcagatgaagatttctcagat
tttgatgaaaaaactgatgatgaagactttgtcccatcagatgctagtccacctaagacc
aaaacttccccaaaacttactaacaaagacctgaaaccacagaaaagtgctatgtcagac
cttgaagctgatgatgctaaggacagtgtaccactgtcttcaagccctcctgctacacat
ttcccaaatgaaactgaaattacaaacacagttcctnaaaagaatgtgacagtgaagaag
acagcagcaaaaagtcagtcttccacctccactaccggtgccaaaaaaagggctgcccct
aaaggaactaaaagggaaccagctttgaattctggtgtctctcaaaagcctgatcctgcc
aaaaccaagattcgccgcaaaaggaagccatccacttctgatgattctgactctaatttt
gagaaaattgtttctaaagcagtcacaagcaagaaatccaggggggagagtgatgacttc
catatggactttgactcagctgtggctcctcgggcaaaatctgtgcgggcaaagaaacct
ataaagtacctggaagagtcagatgaagatgatctgttttaa
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integrated database retrieval system
