Rhinopithecus bieti (black snub-nosed monkey): 108538668
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Entry
108538668 CDS
T04641
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01521
EGFR tyrosine kinase inhibitor resistance
rbb01522
Endocrine resistance
rbb04010
MAPK signaling pathway
rbb04014
Ras signaling pathway
rbb04015
Rap1 signaling pathway
rbb04066
HIF-1 signaling pathway
rbb04068
FoxO signaling pathway
rbb04081
Hormone signaling
rbb04114
Oocyte meiosis
rbb04140
Autophagy - animal
rbb04144
Endocytosis
rbb04150
mTOR signaling pathway
rbb04151
PI3K-Akt signaling pathway
rbb04152
AMPK signaling pathway
rbb04211
Longevity regulating pathway
rbb04213
Longevity regulating pathway - multiple species
rbb04510
Focal adhesion
rbb04520
Adherens junction
rbb04550
Signaling pathways regulating pluripotency of stem cells
rbb04730
Long-term depression
rbb04913
Ovarian steroidogenesis
rbb04914
Progesterone-mediated oocyte maturation
rbb05200
Pathways in cancer
rbb05202
Transcriptional misregulation in cancer
rbb05205
Proteoglycans in cancer
rbb05214
Glioma
rbb05215
Prostate cancer
rbb05218
Melanoma
rbb05224
Breast cancer
rbb05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108538668 (IGF1R)
04014 Ras signaling pathway
108538668 (IGF1R)
04015 Rap1 signaling pathway
108538668 (IGF1R)
04066 HIF-1 signaling pathway
108538668 (IGF1R)
04068 FoxO signaling pathway
108538668 (IGF1R)
04151 PI3K-Akt signaling pathway
108538668 (IGF1R)
04152 AMPK signaling pathway
108538668 (IGF1R)
04150 mTOR signaling pathway
108538668 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
108538668 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
108538668 (IGF1R)
04140 Autophagy - animal
108538668 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
108538668 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
108538668 (IGF1R)
04520 Adherens junction
108538668 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
108538668 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
108538668 (IGF1R)
04914 Progesterone-mediated oocyte maturation
108538668 (IGF1R)
09156 Nervous system
04730 Long-term depression
108538668 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
108538668 (IGF1R)
04213 Longevity regulating pathway - multiple species
108538668 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108538668 (IGF1R)
05202 Transcriptional misregulation in cancer
108538668 (IGF1R)
05205 Proteoglycans in cancer
108538668 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
108538668 (IGF1R)
05214 Glioma
108538668 (IGF1R)
05218 Melanoma
108538668 (IGF1R)
05215 Prostate cancer
108538668 (IGF1R)
05224 Breast cancer
108538668 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108538668 (IGF1R)
01522 Endocrine resistance
108538668 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rbb01001
]
108538668 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
rbb04090
]
108538668 (IGF1R)
Enzymes [BR:
rbb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
108538668 (IGF1R)
Protein kinases [BR:
rbb01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
108538668 (IGF1R)
CD molecules [BR:
rbb04090
]
Proteins
108538668 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
108538668
NCBI-ProteinID:
XP_017742373
LinkDB
All DBs
Position
Unknown
AA seq
1340 aa
AA seq
DB search
MLTSICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLL
FRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNA
DLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPMCEKTTINNEYNYRCWT
TNRCQKMCPSACGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPN
TYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGP
CPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGY
VKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMY
FAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTWKNRIII
TWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGIL
LHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQL
IVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENP
KTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVAN
TTMSSRSRNTTAADTYNITDLEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCN
HEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEI
KYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAK
TGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVY
VPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEF
LNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPP
SLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYR
KGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVME
GGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKDEMEPGFREVSFYYSEENKL
PEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYA
HMNGGRKNERALPLPQSSTC
NT seq
4023 nt
NT seq
+upstream
nt +downstream
nt
atgttaacatcaatctgtgggccgggcattgacatccgcaacgactatcagcagctgaag
cgcctggagaactgcacggtgatcgagggctaccttcacatcctgctcatctccaaggcc
gaggactaccgcagctaccgcttccccaagctcacggtcatcaccgagtacttgcttttg
ttccgagtggctggcctagagagcctcggagacctgttccccaacctcacggtaatccgc
ggctggaaactcttctacaactacgccctggtcatctttgagatgaccaatctcaaggat
attgggctttacaacctgaggaacattactcggggggccatcaggattgagaaaaatgct
gacctctgttacctctccactgtggactggtccctgatcctggatgcagtgtccaataac
tacattgtggggaataagcccccaaaggaatgtggggacctgtgtccaggtaccatggag
gagaagccgatgtgcgagaagaccaccatcaacaatgagtacaactaccgctgctggacc
acaaaccgctgccagaaaatgtgcccgagcgcatgtgggaagagggcatgcaccgagaac
aacgagtgctgccaccccgagtgcctgggcagctgcagcgcgcctgacaacgacacggcc
tgtgtagcttgccgccactactactacgccggtgtctgcgtgcctgcctgcccgcccaac
acctacaggtttgagggctggcgctgtgtggaccgtgacttctgcgccaacatcctcagc
gctgagagcagcgactccgagggtttcgtgatccacgacggcgagtgcatgcaggagtgc
ccctcaggcttcatccgcaacggcagccagagcatgtactgcatcccttgtgaaggtcct
tgccccaaggtctgtgaggaagagaagaaaacaaagaccattgattctgttacttctgct
cagatgctccaaggatgcaccatcttcaagggcaatttgctcattaacatccgacggggg
aataacattgcttcagaactggagaacttcatgggtctcatcgaggtggtgacgggctac
gtgaagatccgccattcccatgccttggtctccttgtccttcctaaaaaaccttcgcctc
atcttaggagaggagcagctagaagggaattactccttctacgtcctcgacaaccagaac
ttgcagcaactatgggactgggaccaccgcaacctgaccatcaaagcagggaaaatgtac
tttgctttcaatcccaaattgtgtgtttcggaaatttaccgcatggaggaagtgacgggg
actaaagggcgccaaagcaaaggggacataaacaccaggaacaacggggagagagcctcc
tgtgaaagtgacgtcctgcatttcacctccaccaccacgtggaagaatcgcatcatcata
acctggcaccggtaccggccccctgactacagggatctcatcagcttcaccgtttactac
aaggaagcaccttttaagaatgtcacggagtatgatgggcaggatgcctgcggctccaac
agctggaacatggtggacgtggacctcccgcccaacaaggacgtggagcccggcatctta
ctgcatgggctgaagccctggactcagtacgccgtttacgtcaaggctgtgaccctcacc
atggtggagaacgaccatatccgtggggccaagagtgagatcttgtacattcgcaccaat
gcttcagttccttccattcccttggacgttctttcagcatcgaactcctcttctcagtta
atcgtgaagtggaaccctccctctctgcccaacggcaacctgagttactacattgtgcgc
tggcagcggcagcctcaggacggctacctttaccggcacaattactgctccaaagacaaa
atccccatcaggaagtatgccgacggtaccatcgacattgaggaggtcacagagaacccg
aagactgaggtgtgtggtggagagaaagggccttgctgcgcctgccccaaaactgaagct
gagaagcaggctgagaaggaggaggctgagtaccgcaaagtctttgagaatttcctgcac
aactccatctttgtgcccagacctgaaaggaagcggagagatgtcatgcaagtggccaac
accaccatgtccagccgaagcaggaacaccacggcggcagacacctacaacattacagat
ctggaagagctagagacagagtaccctttctttgagagcagagtggataataaggagaga
actgtcatttctaaccttcgacctttcacattgtaccgcattgatatccacagctgcaac
cacgaggctgagaaactgggctgcagcgcctccaactttgtctttgcaaggactatgccc
gcagaaggagcagatgacattcctgggccagtgacctgggagccaaggcctgaaaactcc
atctttttaaagtggccagaacctgagaatcccaatggattgattctaatgtatgaaata
aaatacggatcacaagttgaggatcagcgagaatgtgtgtccagacaggaatacaggaag
tatggaggggccaagctaaaccggctaaacccggggaactacacagcccggattcaggcc
acatctctctctgggaatgggtcgtggacagatcctgtgttcttctatgtccaggccaaa
acaggatatgaaaacttcatccatcttatcatcgctctgcctgtcgctgtcctgttgatc
gtgggagggttggtgattatgctgtacgtcttccatagaaagagaaataacagcaggctg
gggaatggagtgctgtacgcatctgtgaacccagagtacttcagcgctgcagatgtgtat
gttcctgatgagtgggaggtggctcgggagaagatcaccatgagccgggaacttgggcag
gggtcgtttgggatggtctatgaaggagttgccaagggtgtggtgaaagacgaacctgaa
accagagtggccattaaaacagtgaacgaggccgcgagcatgcgtgaaaggatcgagttt
ctcaacgaggcttctgtgatgaaggagttcaattgtcaccatgtggtgcggttgctgggt
gtggtgtcccagggccagccaacgctggtcatcatggaactgatgacacggggcgatctc
aaaagttatctccggtctctgaggccagaaatggagaataatccagtcctagcacctcca
agcctaagcaagatgattcagatggctggagagattgcagacggcatggcatacctgaac
gccaacaagttcgtccacagagaccttgctgcccggaattgcatggtagccgaggatttc
acagtcaaaattggagattttgggatgacgcgagatatctatgaaacagactattaccgg
aaaggagggaaagggctgttgcccgtgcgctggatgtctcccgagtccctcaaggatgga
gtcttcaccacttactcagacgtctggtccttcggggttgtcctctgggagatcgccaca
ctggccgagcagccctaccagggcttgtccaacgagcaagtccttcgcttcgtcatggag
ggtggccttctggacaagccagacaactgccccgacatgctgtttgaattgatgcgcatg
tgctggcagtacaaccccaagatgaggccttccttcctggagatcatcagcagcatcaaa
gacgagatggagcctggcttccgggaggtctccttctactacagcgaggagaacaagctg
cccgagccagaggagctggacctggagccagagaacatggagagcgtccccctggacccc
tcggcctcctcgtcctccctgccactgcccgacagacactcaggacacaaggctgagaac
ggccccggccctggagtgctggtcctccgcgccagctttgatgagagacagccttacgca
cacatgaacggtggccgcaagaacgagcgggccttgccgctgccccagtcttcgacctgc
tga
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integrated database retrieval system
