KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108539422
Entry
108539422         CDS       T04641                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01522  Endocrine resistance
rbb04010  MAPK signaling pathway
rbb04015  Rap1 signaling pathway
rbb04068  FoxO signaling pathway
rbb04071  Sphingolipid signaling pathway
rbb04114  Oocyte meiosis
rbb04148  Efferocytosis
rbb04218  Cellular senescence
rbb04261  Adrenergic signaling in cardiomyocytes
rbb04370  VEGF signaling pathway
rbb04380  Osteoclast differentiation
rbb04550  Signaling pathways regulating pluripotency of stem cells
rbb04611  Platelet activation
rbb04613  Neutrophil extracellular trap formation
rbb04620  Toll-like receptor signaling pathway
rbb04621  NOD-like receptor signaling pathway
rbb04622  RIG-I-like receptor signaling pathway
rbb04625  C-type lectin receptor signaling pathway
rbb04657  IL-17 signaling pathway
rbb04658  Th1 and Th2 cell differentiation
rbb04659  Th17 cell differentiation
rbb04660  T cell receptor signaling pathway
rbb04664  Fc epsilon RI signaling pathway
rbb04668  TNF signaling pathway
rbb04670  Leukocyte transendothelial migration
rbb04714  Thermogenesis
rbb04722  Neurotrophin signaling pathway
rbb04723  Retrograde endocannabinoid signaling
rbb04728  Dopaminergic synapse
rbb04750  Inflammatory mediator regulation of TRP channels
rbb04912  GnRH signaling pathway
rbb04914  Progesterone-mediated oocyte maturation
rbb04917  Prolactin signaling pathway
rbb04926  Relaxin signaling pathway
rbb04932  Non-alcoholic fatty liver disease
rbb04933  AGE-RAGE signaling pathway in diabetic complications
rbb04935  Growth hormone synthesis, secretion and action
rbb04936  Alcoholic liver disease
rbb05014  Amyotrophic lateral sclerosis
rbb05020  Prion disease
rbb05022  Pathways of neurodegeneration - multiple diseases
rbb05132  Salmonella infection
rbb05133  Pertussis
rbb05135  Yersinia infection
rbb05140  Leishmaniasis
rbb05142  Chagas disease
rbb05145  Toxoplasmosis
rbb05152  Tuberculosis
rbb05161  Hepatitis B
rbb05163  Human cytomegalovirus infection
rbb05167  Kaposi sarcoma-associated herpesvirus infection
rbb05169  Epstein-Barr virus infection
rbb05170  Human immunodeficiency virus 1 infection
rbb05171  Coronavirus disease - COVID-19
rbb05205  Proteoglycans in cancer
rbb05208  Chemical carcinogenesis - reactive oxygen species
rbb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rbb05415  Diabetic cardiomyopathy
rbb05417  Lipid and atherosclerosis
rbb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108539422 (MAPK11)
   04015 Rap1 signaling pathway
    108539422 (MAPK11)
   04370 VEGF signaling pathway
    108539422 (MAPK11)
   04668 TNF signaling pathway
    108539422 (MAPK11)
   04068 FoxO signaling pathway
    108539422 (MAPK11)
   04071 Sphingolipid signaling pathway
    108539422 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    108539422 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    108539422 (MAPK11)
   04218 Cellular senescence
    108539422 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    108539422 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    108539422 (MAPK11)
   04613 Neutrophil extracellular trap formation
    108539422 (MAPK11)
   04620 Toll-like receptor signaling pathway
    108539422 (MAPK11)
   04621 NOD-like receptor signaling pathway
    108539422 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    108539422 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    108539422 (MAPK11)
   04660 T cell receptor signaling pathway
    108539422 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    108539422 (MAPK11)
   04659 Th17 cell differentiation
    108539422 (MAPK11)
   04657 IL-17 signaling pathway
    108539422 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    108539422 (MAPK11)
   04670 Leukocyte transendothelial migration
    108539422 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    108539422 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    108539422 (MAPK11)
   04917 Prolactin signaling pathway
    108539422 (MAPK11)
   04926 Relaxin signaling pathway
    108539422 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    108539422 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    108539422 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    108539422 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    108539422 (MAPK11)
   04722 Neurotrophin signaling pathway
    108539422 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    108539422 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    108539422 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    108539422 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    108539422 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    108539422 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108539422 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    108539422 (MAPK11)
   05161 Hepatitis B
    108539422 (MAPK11)
   05171 Coronavirus disease - COVID-19
    108539422 (MAPK11)
   05163 Human cytomegalovirus infection
    108539422 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    108539422 (MAPK11)
   05169 Epstein-Barr virus infection
    108539422 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    108539422 (MAPK11)
   05135 Yersinia infection
    108539422 (MAPK11)
   05133 Pertussis
    108539422 (MAPK11)
   05152 Tuberculosis
    108539422 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    108539422 (MAPK11)
   05140 Leishmaniasis
    108539422 (MAPK11)
   05142 Chagas disease
    108539422 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    108539422 (MAPK11)
   05020 Prion disease
    108539422 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    108539422 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108539422 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    108539422 (MAPK11)
   05415 Diabetic cardiomyopathy
    108539422 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    108539422 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    108539422 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    108539422 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    108539422 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rbb01001]
    108539422 (MAPK11)
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     108539422 (MAPK11)
Protein kinases [BR:rbb01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   108539422 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975
Other DBs
NCBI-GeneID: 108539422
NCBI-ProteinID: XP_017743602
UniProt: A0A2K6MF86
LinkDB
Position
Unknown
AA seq 364 aa
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFHGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
EIEQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcgggccctcgcgccggcttctaccggcaggagctgaacaagaccgtgtgggaggtg
ccgcagcggctgcaggggctgcgcccggtgggctcgggcgcctacggctccgtctgttcg
gcctacgacgcgcggctgcgccagaaggtggcggtgaagaagctgtcgcgccccttccag
tcgctgatccacgcgcgcaggacgtaccgggagctgcggctgctcaagcacctgaagcac
gagaacgtcatcgggcttctggacgtcttcacgccggccacgtctatcgaggacttcagc
gaagtgtacttggtgaccaccctcatgggcgccgacctgaacaacatcgtcaagtgccag
gcgctgagcgacgagcacgttcagttcctggtttaccaactgctgcgcgggctaaagtac
atccactcggcggggatcatccaccgggacctgaagcccagcaacgtggctgtgaacgag
gactgtgagctcaggatcctggacttcgggctggcgcgccaggcggacgaggagatgacc
ggctatgtggccacgcgctggtaccgggcacctgagatcatgctaaactggatgcattac
aaccagacagtggacatctggtccgtgggctgcatcatggctgagctgctccagggcaag
gccctcttcccgggaagcgactacattgaccagctgaagcgcatcatggaagtggtgggc
acacccagccccgaggttctggcaaagatctcctcagaacacgcccggacatatatccag
tccctgccccccatgccccagaaggacctgagcagcatcttccatggagccaaccccctg
gccatagacctccttggaaggatgctggtgctggacagtgaccagagggtcagtgccgcc
gaggcactggcccacgcctacttcagccagtaccacgaccctgaggatgagccagaggcc
gagccgtatgatgagagcgttgaggccaaggagcgcacgctggaggagtggaaggagctc
acctaccaggaagtcctcagcttcaagcccccagagccaccgaagccacctggcagcctg
gagattgagcagtga

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