Rhinopithecus bieti (black snub-nosed monkey): 108540946
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Entry
108540946 CDS
T04641
Symbol
ADCY4
Name
(RefSeq) adenylate cyclase type 4 isoform X1
KO
K08044
adenylate cyclase 4 [EC:
4.6.1.1
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00230
Purine metabolism
rbb01100
Metabolic pathways
rbb01522
Endocrine resistance
rbb04015
Rap1 signaling pathway
rbb04020
Calcium signaling pathway
rbb04022
cGMP-PKG signaling pathway
rbb04024
cAMP signaling pathway
rbb04062
Chemokine signaling pathway
rbb04072
Phospholipase D signaling pathway
rbb04081
Hormone signaling
rbb04082
Neuroactive ligand signaling
rbb04114
Oocyte meiosis
rbb04211
Longevity regulating pathway
rbb04213
Longevity regulating pathway - multiple species
rbb04261
Adrenergic signaling in cardiomyocytes
rbb04270
Vascular smooth muscle contraction
rbb04371
Apelin signaling pathway
rbb04540
Gap junction
rbb04611
Platelet activation
rbb04713
Circadian entrainment
rbb04714
Thermogenesis
rbb04723
Retrograde endocannabinoid signaling
rbb04724
Glutamatergic synapse
rbb04725
Cholinergic synapse
rbb04727
GABAergic synapse
rbb04742
Taste transduction
rbb04750
Inflammatory mediator regulation of TRP channels
rbb04911
Insulin secretion
rbb04912
GnRH signaling pathway
rbb04913
Ovarian steroidogenesis
rbb04914
Progesterone-mediated oocyte maturation
rbb04915
Estrogen signaling pathway
rbb04916
Melanogenesis
rbb04918
Thyroid hormone synthesis
rbb04921
Oxytocin signaling pathway
rbb04923
Regulation of lipolysis in adipocytes
rbb04925
Aldosterone synthesis and secretion
rbb04926
Relaxin signaling pathway
rbb04927
Cortisol synthesis and secretion
rbb04928
Parathyroid hormone synthesis, secretion and action
rbb04934
Cushing syndrome
rbb04935
Growth hormone synthesis, secretion and action
rbb04970
Salivary secretion
rbb04971
Gastric acid secretion
rbb04972
Pancreatic secretion
rbb04976
Bile secretion
rbb05032
Morphine addiction
rbb05163
Human cytomegalovirus infection
rbb05166
Human T-cell leukemia virus 1 infection
rbb05200
Pathways in cancer
rbb05207
Chemical carcinogenesis - receptor activation
rbb05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
108540946 (ADCY4)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
108540946 (ADCY4)
04371 Apelin signaling pathway
108540946 (ADCY4)
04020 Calcium signaling pathway
108540946 (ADCY4)
04072 Phospholipase D signaling pathway
108540946 (ADCY4)
04024 cAMP signaling pathway
108540946 (ADCY4)
04022 cGMP-PKG signaling pathway
108540946 (ADCY4)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
108540946 (ADCY4)
04081 Hormone signaling
108540946 (ADCY4)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
108540946 (ADCY4)
09144 Cellular community - eukaryotes
04540 Gap junction
108540946 (ADCY4)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
108540946 (ADCY4)
04062 Chemokine signaling pathway
108540946 (ADCY4)
09152 Endocrine system
04911 Insulin secretion
108540946 (ADCY4)
04923 Regulation of lipolysis in adipocytes
108540946 (ADCY4)
04912 GnRH signaling pathway
108540946 (ADCY4)
04913 Ovarian steroidogenesis
108540946 (ADCY4)
04915 Estrogen signaling pathway
108540946 (ADCY4)
04914 Progesterone-mediated oocyte maturation
108540946 (ADCY4)
04921 Oxytocin signaling pathway
108540946 (ADCY4)
04926 Relaxin signaling pathway
108540946 (ADCY4)
04935 Growth hormone synthesis, secretion and action
108540946 (ADCY4)
04918 Thyroid hormone synthesis
108540946 (ADCY4)
04928 Parathyroid hormone synthesis, secretion and action
108540946 (ADCY4)
04916 Melanogenesis
108540946 (ADCY4)
04925 Aldosterone synthesis and secretion
108540946 (ADCY4)
04927 Cortisol synthesis and secretion
108540946 (ADCY4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
108540946 (ADCY4)
04270 Vascular smooth muscle contraction
108540946 (ADCY4)
09154 Digestive system
04970 Salivary secretion
108540946 (ADCY4)
04971 Gastric acid secretion
108540946 (ADCY4)
04972 Pancreatic secretion
108540946 (ADCY4)
04976 Bile secretion
108540946 (ADCY4)
09156 Nervous system
04724 Glutamatergic synapse
108540946 (ADCY4)
04727 GABAergic synapse
108540946 (ADCY4)
04725 Cholinergic synapse
108540946 (ADCY4)
04723 Retrograde endocannabinoid signaling
108540946 (ADCY4)
09157 Sensory system
04742 Taste transduction
108540946 (ADCY4)
04750 Inflammatory mediator regulation of TRP channels
108540946 (ADCY4)
09149 Aging
04211 Longevity regulating pathway
108540946 (ADCY4)
04213 Longevity regulating pathway - multiple species
108540946 (ADCY4)
09159 Environmental adaptation
04713 Circadian entrainment
108540946 (ADCY4)
04714 Thermogenesis
108540946 (ADCY4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108540946 (ADCY4)
05207 Chemical carcinogenesis - receptor activation
108540946 (ADCY4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
108540946 (ADCY4)
05163 Human cytomegalovirus infection
108540946 (ADCY4)
09165 Substance dependence
05032 Morphine addiction
108540946 (ADCY4)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
108540946 (ADCY4)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
108540946 (ADCY4)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
108540946 (ADCY4)
Enzymes [BR:
rbb01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
108540946 (ADCY4)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_cyc
Adcy_cons_dom
AC_N
CD52
Motif
Other DBs
NCBI-GeneID:
108540946
NCBI-ProteinID:
XP_017745742
LinkDB
All DBs
Position
Unknown
AA seq
1190 aa
AA seq
DB search
MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLGIVLCALAALLAVAWASGRELTSDPS
FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWVALLALGHAFLFTGGVVSAWDQV
SYFLFVIFTVYAMLPLGMRDAAVAGLASSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL
FLCGNVAGVYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG
AYAVEDAGMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR
YLESWGAAKPFAHLSHVDSPVSTSTPLQEKTLASFSPQWSLDRSRNPRGLDDELDTGDAK
FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSAIPAFKYYEACTFLVFLSNFI
IQMLVTNRPPALAITYSITFLLFLLLLFVCFSEDLMRCALKGPKMLHWLPALSGLVATRP
GLRIALSTATILLVFAMATTSLDLDSFLEFYSWRAPGNHPSAKLQKRKLRPREAKWLARA
HTVAQSQRSTLDAPHITPPPVRTPVLRFPSLPEIAESTPLDESGPDSSLGQLKPSTSHHC
AQETTCLFSSSSPLQFFFPTSSDCPFQAPNVSSMISNLSWELPGSLPLISVPYSMHCCTL
GFLSCSLFLHMSFELKLLLLLLWLAASCSLFLHSHAWLSDCLIVRLYLGPLDSRPGVLKE
PKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLENVLP
AHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLLNEIIA
DFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMVEFAVALG
SKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQ
VTEETAWALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRSGPPSVTLG
NT seq
3573 nt
NT seq
+upstream
nt +downstream
nt
atggcccgcctcttcagcccccggccaccccccagcgaagacctcttctacgagacctac
tacagcctgagccagcagtacccgctgctgctgctgctgctggggatcgtgctctgtgcg
ctcgcggcgctgctcgcggttgcctgggccagcggcagggagctgacttcagacccgagc
ttcctgaccactgtgctgtgcgcgctgggcggcttctcgctgctgctgggcctcgcttcc
cgcgagcagcgactgcagcgctggacgcgtcctctgtccggcttggtgtgggtcgcgctg
ctagcgctaggccacgccttcctgttcaccgggggcgtggtgagcgcctgggaccaggtg
tcctattttctcttcgtcatcttcacggtgtatgccatgctgcccttgggcatgcgggac
gccgccgtcgcgggcctcgcctcctcactctcgcatctactggtcctggggctgtatctt
gggccacagccggactcacggcctgcactgctgccgcagttggcagcaaatgcggtgctg
ttcctgtgcgggaacgtggcaggagtgtaccacaaggcgctgatggagcgcgccctgcgg
gccacgttccgggaggcactcagctccttgcactcgcgccggcggctggacaccgaaaag
aagcaccaggaacaccttctcttgtccatccttcctgcctacctggcccgagagatgaaa
gcagagatcatggcacggctgcaggcaggacaggggtcacggccagaaagcaccaacaat
ttccacagcctctatgtcaagaggcaccagggagtcagtgtgctgtatgctgacattgtg
ggcttcacgcggctggccagcgagtgttcccctaaggagctggtgctcatgctcaatgag
ctctttggcaagtttgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg
ggggactgttactactgtgtctccggactgccactctcactgccagaccatgccatcaac
tgtgtgcgcatggggctggacatgtgccgggccatcaggaaactgcgggcagccactggc
gtggacatcaacatgcgtgtgggcgtgcactcaggcagtgtactctgtggagtcatcggg
ctgcagaagtggcagtatgacgtttggtcccatgatgttacactggctaaccacatggag
gcaggcggtgtaccagggcgagtgcacatcacaggggctaccctggccctgctggcaggg
gcttatgctgtggaggacgcaggcatggagcatcgggatccctaccttcgggagctaggg
gagcccacttatctggtcattgatccacgggcagaggaggaggatgagaagggcactgca
ggaggcttgctctcctcgcttgagggccccaagatgcgtccatcactgctgatgacccgt
tacctggagtcctggggtgcagccaagccttttgcccacctgagccacgtagacagccct
gtgtccacctccacccctctccaggagaagaccctggcttccttcagcccccagtggagc
ctagatcgaagccgtaacccccgtggactagatgatgaactggacaccggggatgccaag
ttcttccaggtcattgagcagctcaactcacagaaacagtggaagcagtcgaaggacttc
aacccactgacactgtacttcagagagaaggagatggagaaagagtaccgactctctgca
atccccgccttcaaatactatgaagcctgcaccttcctggtttttctctccaacttcatc
atccagatgctagtgacaaacaggcccccagctctggccatcacgtatagcatcaccttc
ctcctcttcctcctcctcctttttgtctgcttctcagaggacctgatgaggtgtgccctg
aaaggccccaagatgctgcattggctgcctgcactgtctggcttggtggccacacgacca
ggactgagaatagccttgagcaccgccaccatcctccttgtctttgccatggccactacc
agcctggatttagactcattcctagaattctattcctggagggcacctgggaatcaccca
tcagccaagttacagaagaggaagctaaggcccagagaggctaagtggctggcaagagct
cacacagtggctcagagtcagagaagtactcttgatgcccctcacataactcctccccca
gtgaggaccccagtgctgaggttcccttccctaccagaaatagcagaatccacccctttg
gacgagtctggccctgactcatctctgggtcagctgaaacccagcacaagccaccattgt
gcccaagaaactacctgcctcttcagctcctcatctcctctgcagttcttcttcccaaca
tcatcagactgccctttccaagctcccaatgtgtcctccatgatttccaacctctcctgg
gagctccctgggtctctgcctctcatcagtgtcccatactccatgcactgctgcacgctg
ggcttcctctcctgctccctctttctgcacatgagcttcgagctgaagctgctgctgctc
ctgctgtggctggcggcatcctgctccctcttcctacactcccacgcctggctgtccgac
tgcctcatcgtccgcctctatctgggccccttggactccaggcccggagtgctgaaggag
cccaaactcatgggtgctatctccttcttcatcttcttcttcaccctccttgtcctggct
cgccagaatgagtactactgccgcctggacttcctgtggaagaagaagctgaggcaggag
cgggaggagacagagacgatggagaacctgactcggctgctcttggagaatgtgctccct
gcacacgtggccccccagttcattggccagaaccggcgcaacgaggatctctaccaccag
tcctacgaatgcgtttgtgtcctcttcgcttcagtcccagacttcaaggagttctactct
gaatccaacatcaatcatgagggcctagagtgtctgaggctgctcaatgaaataattgct
gattttgatgagctgctctccaagcccaagttcagtggggtggagaagatcaagaccatt
ggcagcacctacatggcagccacaggattaaatgccacctctggacaggatgcacaacag
gatgctgaacggagctgcagccaccttggcactatggtggaatttgccgttgccctgggg
tctaagctggacgtcatcaacaagcattcattcaacaacttccgcctgcgtgtggggttg
aaccatggaccagtagtagctggagttattggggcccagaagccacaatatgacatttgg
ggcaacacagtgaacgtggccagccgcatggagagtacaggagtccttggcaaaatccaa
gtgactgaggagacagcctgggccctacagtccctgggctacacctgctacagccggggg
gtcatcaaggtgaaaggcaaagggcagctctgcacctacttcctgaacacagacttgaca
cgaagtggacctccttcagttaccctaggctga
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