Rhinopithecus bieti (black snub-nosed monkey): 108541365
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Entry
108541365 CDS
T04641
Symbol
NF1
Name
(RefSeq) LOW QUALITY PROTEIN: neurofibromin
KO
K08052
neurofibromin 1
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01521
EGFR tyrosine kinase inhibitor resistance
rbb04010
MAPK signaling pathway
rbb04014
Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108541365 (NF1)
04014 Ras signaling pathway
108541365 (NF1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108541365 (NF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PH_NF1
RasGAP
CRAL_TRIO_2
CRAL_TRIO
MIF4G_like_2
Motif
Other DBs
NCBI-GeneID:
108541365
NCBI-ProteinID:
XP_017746353
LinkDB
All DBs
Position
Unknown
AA seq
2797 aa
AA seq
DB search
MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT
ILKNVNNMRIFGEAAEKNLYLSQLIILAALEKCLAGQPKDTMRLDETMLVKQLLPEICHF
LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL
QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT
DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL
DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP
SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN
SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAQSTFKGKVTSLKWKGKP
TDXWKEEHECPLLSHVKLIHAESKLXLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEI
AQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQTLSSTEILEWLR
EILICRNKFLLKNKQADRSSCHFLLFHGVGCDIPSSGNTSQMSMDHEELLRTPGASLRKG
KGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIRC
GVDEVSVHNLLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTH
AKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMT
GFLCALGGVCLQQRSNSGLATYSPPMGPVNERKGSMISVMSSEGNADTPVSKFMDRLLSL
MVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNTQFV
EQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEV
MMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLA
GLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLASL
RHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVL
ADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMF
SKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEV
DPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKAT
VKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKL
MSKILQSIANHVLFTKEEHMRPFNDFVKTNFDAARRFFLDIASDCPTSDAVNHSLSFISD
GNVLALHRLLWNNQEKIGQYLSSNRLLCSFSFRHQVHEKEEFKALKTLSIFYQAGTSKSG
NPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKW
FVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHE
QQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDI
YYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQH
TKIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPA
NNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKH
NDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGG
LGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILA
RYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFS
EETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSL
ETVTEALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHG
QIKQIIRILSKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAV
LQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNF
NSNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAAL
LTVSEEVRSRCSLKHRKSLLLTDISMENVPMDTYPIHHGDPTYRTLKETQPWSSPKGSEG
YLAATYPTVGQTSPRARKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESG
ITTPPKMRRVAETDYEMETQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTV
LATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIH
GIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTY
LPGIDEETSEESLLTPTSPYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELS
PTTGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV
NT seq
8394 nt
NT seq
+upstream
nt +downstream
nt
atggccgcgcacaggccggtggaatgggtccaggccgtggtcagccgcttcgacgagcag
cttccaataaaaacaggacagcagaacacacataccaaagtcagtactgagcacaacaag
gaatgtctaatcaatatttccaaatacaagttttctttggttataagcggcctcactact
atcttaaagaatgttaacaatatgagaatatttggagaagctgctgaaaaaaatttatat
ctctctcagttgattatattggctgcactggaaaaatgtcttgctgggcaaccaaaggac
acaatgagattagatgaaacgatgctggtcaaacagttgctgccagaaatctgccatttt
cttcacacctgtcgtgaaggaaaccagcatgcagctgaacttcggaattctgcctctggg
gttttattttctctcagctgcaacaacttcaatgcagtctttagtcgcatttctaccagg
ttacaggaattaactgtttgttcagaagacaatgttgatgttcatgatatagaattgtta
cagtatatcaatgtggattgtgcaaaattaaaacgactcctgaaggaaacagcatttaaa
tttaaagccctaaagaaggttgcacagttagcagttataaatagcctggaaaaggcattt
tggaactgggtagaaaattatccagatgaatttacaaaactataccagatcccacagact
gatatggctgaatgtgcagaaaagctgtttgacttggtggatggttttgctgaaagcacc
aaacgtaaagcagcagtttggccactgcaaatcattctccttatcttgtgtccagaaata
atccaggatatatccaaggatgtggttgatgaaaacaacatgaataagaagttatttctg
gacagtctacgaaaagctcttgctggccatggaggaagtaggcagctgacagaaagtgct
gcaattgcctgtgtcaaactgtgtaaagcaagtacttacatcaattgggaagataactct
gtcattttcctacttgttcagtccatggtggttgatcttaagaacctgctttttaatcca
agtaagccattctcaagaggcagtcagcctgcagatgtggatctaatgattgactgcctt
gtttcttgctttcgtataagtcctcacaacaaccaacactttaagatctgcctggctcag
aattcaccttctacatttcactatgtgctggtaaattcactccatcgaatcatcaccaat
tcggcattggattggtggcctaagattgatgctgtgtattgtcactcggttgaacttcga
aatatgtttggtgaaacacttcataaagcagtgcaaggttgtggagcacacccagcaata
cgaatggcacagtctacatttaaaggaaaagtaacaagccttaaatggaaaggaaaacct
acagatncctggaaagaagaacatgagtgtcctctcttgtcccatgtgaaactaattcat
gcagaatccaaactctagctttgcaatccaagaaaacaggggcccgaaacccaaggcagt
acagcggagttaattacagggctcgtccaactggtccctcagtcacacatgccagagatt
gcgcaggaagcaatggaggctctgctggttcttcatcagttagatagcattgatttgtgg
aatcctgatgctcctgtagaaacattttgggagattagctcacaaatgcttttttacatc
tgcaagaaattaactagtcatcaaacgcttagtagcacagaaattctcgagtggttgcgg
gaaattttgatctgcaggaataaatttcttcttaaaaataagcaggcagatagaagttcc
tgtcactttctcctttttcatggagtaggatgtgatattccttctagtggaaataccagt
caaatgtccatggatcacgaagaattactacgtactcctggagcctctctccggaaggga
aaagggaactcctctatggatagtgcagcaggatgcagcggaacccccccgatttgccga
caagcccagaccaaactagaagtggccctgtacatgtttctgtggaaccctgacactgaa
gctgttctggttgccatgtcctgtttccgccacctctgtgaggaagcagatatccggtgt
ggggtggatgaagtgtcagtgcataacctcttgcccaactataacacattcatggagttt
gcctctgtcagcaatatgatgtcaacaggaagagcagcacttcagaaaagagtgatggca
ctgctgaggcgcattgagcatcccactgcaggaaacactgaggcttgggaagatacacat
gcaaaatgggaacaagcaacaaaactaatccttaactatccaaaagccaaaatggaagat
ggccaggctgctgaaagccttcacaagaccattgttaagaggcgaatgtcccatgtgagt
ggaggaggatccatagatttgtctgacacagactccctacaggaatggatcaacatgact
ggcttcctttgtgcccttgggggagtgtgcctccagcagagaagcaattctggcctggca
acctatagcccacccatgggtccagtcaatgaacgtaagggttccatgatttcagtgatg
tcctcagagggaaacgccgatacacctgtcagcaaatttatggatcggctcttgtcctta
atggtgtgtaaccatgagaaagtgggacttcaaatacggaccaatgttaaggatctggtg
ggtctagaattgagtcctgctctgtatccaatgctatttaacaaattgaagaataccatc
agcaagttttttgactcccaaggacaggttttattgactgataccaatactcaatttgta
gaacaaaccatagctataatgaagaacttgctagataatcataccgaaggcagctctgaa
catctggggcaagctagcattgaaacaatgatgttaaatctggtcaggtatgttcgtgtg
cttgggaatatggtccatgcgattcaaataaaaacaaaactgtgtcaattagttgaagta
atgatggcaaggagagatgacctctcattttgccaagagatgaaatttaggaataagatg
gtagaatacctgacagactgggttatgggaacatcaaaccaagcagcggatgatgatgta
aaatgtcttacaagagatttggaccaggcaagcatggaagcagtagtttcacttctagct
ggtctccctctgcagcctgaagaaggagatggtgtggaattgatggaagccaaatcacag
ttatttcttaaatacttcacattatttatgaaccttttgaatgactgcagtgaagttgaa
gatgaaaatgcacaaacaggtggcaggaaacgtggcatgtctcggaggctggcatcactg
aggcactgtacagtccttgcaatgtcaaacttactcaatgccaacgtagacagtggtctc
atgcactccataggcttaggttaccacaaggatctccagacaagagctacatttatggaa
gttctgacaaaaatccttcaacaaggcacagaatttgacacacttgcagaaacggtattg
gctgatcggtttgagagattggtggaactggtcacaatgatgggtgatcaaggagaactc
cctatagcgatggctctggccaatgtggttccttgttctcagtgggatgaactagctcga
gttctggttactctgtttgattctcggcatttactctaccaactgctctggaacatgttt
tcaaaagaagtagaattggcagactccatgcagactcttttccgaggcaacagcttggcc
agtaaaataatgacgttctgtttcaaggtatatggtgctacctatctacagaaactcctg
gatcctttattacgaattgtgatcacatcctctgattggcaacatgttagctttgaagtg
gatcctaccaggttagaaccatcagagagccttgaggaaaaccagcggaacctccttcag
atgactgaaaagttcttccatgccatcatcagttcctcctcagaattcccccctcaactt
cgaagtgtgtgccactgtttataccaggcaacttgccactccctactgaataaagctaca
gtaaaagaaaaaaaggaaaacaaaaaatcagtggttagccagcgtttccctcagaacagc
atcggtgcagtaggaagtgccatgttcctcagatttatcaatcctgccattgtctcaccg
tatgaagcagggattttagataaaaagccaccacctagaattgaaaggggcttgaagtta
atgtcaaagatacttcagagtatcgccaatcatgttctcttcacaaaagaagaacatatg
cggcctttcaacgattttgtgaaaaccaactttgatgcagcacgaaggttttttcttgat
atagcatctgattgtcctacaagtgatgcagtaaatcatagtctttccttcatcagtgac
ggcaatgtgcttgctttacatcgtctactctggaacaatcaggagaaaattggccagtat
ctttccagcaacaggttactctgttctttttcttttaggcatcaggtacatgaaaaagaa
gaattcaaggctttgaaaacgttaagtattttctaccaagctgggacttccaaatctgga
aatcctattttttattatgttgcacggaggttcaaaactggtcaaatcaatggtgatttg
ctgatataccatgtcttactgactttaaagccatattatgcaaagccatatgaaattgta
gtggaccttacccataccgggcctagcaatcgctttaaaacagactttctttctaagtgg
tttgttgtttttcctggctttgcttacgacaacgtctctgcagtctatatctataactgt
aactcctgggtcagggagtacaccaagtatcatgagcggctgctaactggcctcaaaggt
agcaaaaggcttgttttcatagactgtcctgggaaactggctgagcacatagagcacgaa
caacagaaactacctgctgccactttggctttagaagaggacctgaaggtattccacaat
gctctcaagctagctcacaaagataccaaagtttctattaaagttggttctactgctgtc
caagtaacctcagcagagcgaacaaaagtcctaggacaatcagtctttttaaatgacatc
tattatgcttcggaaattgaagaaatctgcctagtagatgagaaccagttcaccttaacc
attgcaaaccagggcacgccactcaccttcatgcaccaggagtgtgaagccattgtccag
tctatcattcatatccggacccgctgggagctgtcacagcccgactctatcccccaacac
accaagattcggccaaaagatgtccctgggacactgctcaatatcgcattacttaattta
ggcagttctgacccgagtttacggtcagctgcctataatcttctgtgtgccttaacttgt
acctttaatttaaaaatcgagggccagttactagagacatcaggtttatgtatccctgcc
aacaacaccctctttattgtctctattagtaagacactggcagccaatgagccacacctc
acgttagaatttttggaagagtgtatttctggatttagcaaatctagtattgaattgaaa
cacctttgtttggaatacatgactccatggctgtcaaatctagttcgtttttgcaagcat
aatgatgatgccaaacgacaaagagttactgctattcttgacaagctgataacaatgacc
atcaatgaaaaacagatgtacccatctattcaagcaaaaatatggggaagccttgggcag
attacagatctgcttgatgttgtactagacagtttcatcaaaaccagtgcaacaggtggc
ttgggatcaataaaagctgaggtgatggcagatactgctgtagctttggcttctggaaat
gtgaaattggtttcgagcaaggttattggaaggatgtgcaaaataattgacaagacatgc
ttatctccaactcctactttagaacaacatcttatgtgggatgatattgctattttagca
cgctacatgctgatgctgtccttcaacaattcccttgatgtggcagctcatcttccctac
ctcttccacgttgttactttcttagtagccacaggtccgctctcccttagagcttccaca
catggactggtcattaatatcattcactctctgtgtacttgttcacagcttcattttagt
gaagagaccaagcaagttttgagactcagtctgacagaattctcattacccaaattttac
ttgctgtttggcattagcaaagtcaagtcagctgctgtcattgccttccgttccagttac
cgggataggtcattctctcctggctcctatgagagagagacttttgctttgacatccttg
gaaacggtcacagaagctttgttggagatcatggaggcatgcatgagagatattccaacg
tgcaagtggctggaccagtggacagaactagctcaaagatttgcattccaatataatcca
tccctgcaaccaagagctcttgttgtctttgggtgtattagcaaacgagtgtctcatggg
cagataaagcagattatccgtattcttagcaaggcacttgagagttgcttaaaaggacct
gatacttacaacagtcaagttctgatagaagctacagtaatagcattaaccaaattacag
ccacttcttaataaggactcacctctgcacaaagccctcttttgggtagctgtggctgtg
ctgcagcttgatgaagtcaacttgtattcagcaggcaccgcacttcttgaacaaaacctg
catactttagatagtctccgtatattcaacgacaagagtccagaggaagtatttatggca
atccggaatcctctggagtggcactgcaagcaaatggatcattttgttggactcaatttc
aactctaactttaactttgcattggttggacaccttttaaaagggtacaggcatccttca
cctgctattgttgcaagaacagtcagaattttacatacactactaactctggttaacaaa
cacagaaattgtgacaaatttgaagtgaatacacagagcgtggcctacttagcagcttta
cttacagtgtctgaagaagttcgaagtcgctgcagcctaaaacatagaaagtcacttctt
cttactgatatttcaatggaaaatgttcctatggatacatatcccattcatcatggtgat
cctacctataggacactaaaggagactcagccatggtcctctcccaaaggttctgaagga
taccttgcagccacctatccaactgtcggccagaccagtccccgagccaggaaatccatg
agcttggacatggggcagccttctcaggccaacactaagaagttgcttggaacaaggaaa
agttttgatcacctgatatcagacacaaaggctcctaaaaggcaagaaatggaatcaggg
atcacaacaccccccaaaatgaggagagtagcagaaactgattatgaaatggaaactcag
aggatttcctcatcacaacagcacccacatttacgtaaggtttcggtgtctgaatcaaat
gttctcttggatgaagaagtacttactgatccaaaaatccaggcgctgcttcttactgtt
ctagctacactggtaaaatataccacagatgagtttgatcaacgaattctttatgaatac
ttagcagaggccagtgttgtgtttcccaaagtatttcctgttgtgcataatttgttggac
tctaagatcaacaccctgttatcactgtgccaagatccaaatctgttaaatccaatccat
ggaattgtgcagagtgtggtgtaccatgaagaatccccaccacaataccaaacatcttac
ctgcaaagttttggttttaatggcttgtggcggtttgcaggacccttttcaaagcaaaca
caaattccagactatgctgagcttattgttaagtttcttgatgccttgattgacacgtac
ctgcctggaattgatgaagaaaccagtgaggaatccctcctgacacccacatctccttac
cctcctgcactgcagagccagcttagtatcactgccaaccttaacctctctaattccatg
acctcacttgcaacttcccagcattccccaggaatcgacaaggagaacgttgaactctcc
cctaccactggccactgtaacagtggacgaactcgccacggatccgcaagccaagtgcag
aagcaaagaagtgctggcagtttcaaacgtaatagcattaagaagatcgtgtga
DBGET
integrated database retrieval system
