KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108541757
Entry
108541757         CDS       T04641                                 
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase-3 beta isoform X1
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01521  EGFR tyrosine kinase inhibitor resistance
rbb04012  ErbB signaling pathway
rbb04062  Chemokine signaling pathway
rbb04110  Cell cycle
rbb04150  mTOR signaling pathway
rbb04151  PI3K-Akt signaling pathway
rbb04310  Wnt signaling pathway
rbb04340  Hedgehog signaling pathway
rbb04360  Axon guidance
rbb04390  Hippo signaling pathway
rbb04510  Focal adhesion
rbb04550  Signaling pathways regulating pluripotency of stem cells
rbb04657  IL-17 signaling pathway
rbb04660  T cell receptor signaling pathway
rbb04662  B cell receptor signaling pathway
rbb04722  Neurotrophin signaling pathway
rbb04728  Dopaminergic synapse
rbb04910  Insulin signaling pathway
rbb04916  Melanogenesis
rbb04917  Prolactin signaling pathway
rbb04919  Thyroid hormone signaling pathway
rbb04931  Insulin resistance
rbb04932  Non-alcoholic fatty liver disease
rbb04934  Cushing syndrome
rbb04935  Growth hormone synthesis, secretion and action
rbb04936  Alcoholic liver disease
rbb05010  Alzheimer disease
rbb05020  Prion disease
rbb05022  Pathways of neurodegeneration - multiple diseases
rbb05135  Yersinia infection
rbb05160  Hepatitis C
rbb05162  Measles
rbb05163  Human cytomegalovirus infection
rbb05165  Human papillomavirus infection
rbb05167  Kaposi sarcoma-associated herpesvirus infection
rbb05200  Pathways in cancer
rbb05210  Colorectal cancer
rbb05213  Endometrial cancer
rbb05215  Prostate cancer
rbb05217  Basal cell carcinoma
rbb05224  Breast cancer
rbb05225  Hepatocellular carcinoma
rbb05226  Gastric cancer
rbb05415  Diabetic cardiomyopathy
rbb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    108541757 (GSK3B)
   04310 Wnt signaling pathway
    108541757 (GSK3B)
   04340 Hedgehog signaling pathway
    108541757 (GSK3B)
   04390 Hippo signaling pathway
    108541757 (GSK3B)
   04151 PI3K-Akt signaling pathway
    108541757 (GSK3B)
   04150 mTOR signaling pathway
    108541757 (GSK3B)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    108541757 (GSK3B)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    108541757 (GSK3B)
   04550 Signaling pathways regulating pluripotency of stem cells
    108541757 (GSK3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    108541757 (GSK3B)
   04657 IL-17 signaling pathway
    108541757 (GSK3B)
   04662 B cell receptor signaling pathway
    108541757 (GSK3B)
   04062 Chemokine signaling pathway
    108541757 (GSK3B)
  09152 Endocrine system
   04910 Insulin signaling pathway
    108541757 (GSK3B)
   04917 Prolactin signaling pathway
    108541757 (GSK3B)
   04935 Growth hormone synthesis, secretion and action
    108541757 (GSK3B)
   04919 Thyroid hormone signaling pathway
    108541757 (GSK3B)
   04916 Melanogenesis
    108541757 (GSK3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    108541757 (GSK3B)
   04722 Neurotrophin signaling pathway
    108541757 (GSK3B)
  09158 Development and regeneration
   04360 Axon guidance
    108541757 (GSK3B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108541757 (GSK3B)
  09162 Cancer: specific types
   05210 Colorectal cancer
    108541757 (GSK3B)
   05225 Hepatocellular carcinoma
    108541757 (GSK3B)
   05226 Gastric cancer
    108541757 (GSK3B)
   05217 Basal cell carcinoma
    108541757 (GSK3B)
   05215 Prostate cancer
    108541757 (GSK3B)
   05213 Endometrial cancer
    108541757 (GSK3B)
   05224 Breast cancer
    108541757 (GSK3B)
  09172 Infectious disease: viral
   05160 Hepatitis C
    108541757 (GSK3B)
   05162 Measles
    108541757 (GSK3B)
   05163 Human cytomegalovirus infection
    108541757 (GSK3B)
   05167 Kaposi sarcoma-associated herpesvirus infection
    108541757 (GSK3B)
   05165 Human papillomavirus infection
    108541757 (GSK3B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    108541757 (GSK3B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108541757 (GSK3B)
   05020 Prion disease
    108541757 (GSK3B)
   05022 Pathways of neurodegeneration - multiple diseases
    108541757 (GSK3B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108541757 (GSK3B)
   05415 Diabetic cardiomyopathy
    108541757 (GSK3B)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    108541757 (GSK3B)
   04932 Non-alcoholic fatty liver disease
    108541757 (GSK3B)
   04931 Insulin resistance
    108541757 (GSK3B)
   04934 Cushing syndrome
    108541757 (GSK3B)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    108541757 (GSK3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rbb01001]
    108541757 (GSK3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:rbb03036]
    108541757 (GSK3B)
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     108541757 (GSK3B)
Protein kinases [BR:rbb01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   108541757 (GSK3B)
Chromosome and associated proteins [BR:rbb03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    108541757 (GSK3B)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH
Other DBs
NCBI-GeneID: 108541757
NCBI-ProteinID: XP_017746876
UniProt: A0A2K6LLG4
LinkDB
Position
Unknown
AA seq 400 aa
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN
VKLPNGRDTPALFNFTTQDANTGDRGQTNNAASASASNST
NT seq 1203 nt   +upstreamnt  +downstreamnt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccggtgcagcagcct
tcagcttttggcagcatgaaagttagcagagacaaggatggcagcaaggtgaccacagtg
gtggcaactcctgggcagggtccagacaggccacaagaagtcagctatacagacactaaa
gtgattggaaatggatcatttggtgtggtatatcaagccaaactttgtgattcaggagaa
ctggtcgccatcaagaaagtattgcaggacaagagatttaagaaccgagagctccagatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactccagtggt
gagaagaaagatgaggtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgctccctgtgatttatgtcaagttg
tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatctgccatcgg
gatattaaaccacagaacctcttgttggatcctgatacagccgtattaaaactctgtgac
tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagatgta
tggtctgctggctgtgtgttggctgagctgttactaggacaaccaatatttccaggggat
agtggtgtggatcagttggtggaaataatcaaggtcctgggaactccaacaagggagcaa
atcagagaaatgaacccaaactacacagaatttaaattccctcaaattaaggcacatcct
tggacgaaggattcgtcaggaacaggacatttcacctcaggagtgcgggtcttccgaccc
cgaactccaccagaggcaattgcactgtgtagccgtctgctggagtatacgccaactgcc
cgactaacaccactggaagcttgtgcacattcattttttgatgaattacgggacccaaat
gtcaaactaccaaatgggcgagacacacctgcactcttcaacttcaccactcaagatgct
aatactggagaccgtggacagaccaataatgctgcttctgcatcagcttccaactccacc
tga

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