Rhinopithecus bieti (black snub-nosed monkey): 108543433
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Entry
108543433 CDS
T04641
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00190
Oxidative phosphorylation
rbb01100
Metabolic pathways
rbb04714
Thermogenesis
rbb04723
Retrograde endocannabinoid signaling
rbb04932
Non-alcoholic fatty liver disease
rbb05010
Alzheimer disease
rbb05012
Parkinson disease
rbb05014
Amyotrophic lateral sclerosis
rbb05016
Huntington disease
rbb05020
Prion disease
rbb05022
Pathways of neurodegeneration - multiple diseases
rbb05208
Chemical carcinogenesis - reactive oxygen species
rbb05415
Diabetic cardiomyopathy
Module
rbb_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
108543433 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
108543433 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
108543433 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
108543433 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
108543433 (NDUFS1)
05012 Parkinson disease
108543433 (NDUFS1)
05014 Amyotrophic lateral sclerosis
108543433 (NDUFS1)
05016 Huntington disease
108543433 (NDUFS1)
05020 Prion disease
108543433 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
108543433 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
108543433 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
108543433 (NDUFS1)
Enzymes [BR:
rbb01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
108543433 (NDUFS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
108543433
NCBI-ProteinID:
XP_017749398
UniProt:
A0A2K6JZX3
LinkDB
All DBs
Position
Unknown
AA seq
727 aa
AA seq
DB search
MLRIPVRKALVGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSRKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGNDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMIRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALVALKDLLNR
VDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYSYDHLGDSPKILQDIASGSHPFSQVLKEAKKPMVVLGSSA
LQRNDGAAILAAVSSIAQKIRMTSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKN
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSVC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttgaggatacctgtaagaaaggccttagtaggcctttctaaatctcctaaaggatgt
gttcgaacaactgccacagcagcaagcaacttgattgaagtatttgttgatggtcagtct
gtcatggtggaaccgggaacgaccgtcctccaagcttgtgagaaggttggcatgcagatc
cctcgattctgttatcatgaaaggttgtctgttgctggaaactgcaggatgtgccttgtt
gaaattgagaaagcccccaaggttgtagctgcttgtgccatgccagtaatgaagggctgg
aatatcctaacaaactcagaaaaatccaggaaagccagggaaggtgtgatggagttctta
ttagcaaatcacccactggactgtcctatttgtgaccagggaggtgaatgtgatctgcag
gaccagtccatgatgtttggaaatgataggagccgatttttagaggggaagcgtgctgtg
gaagacaagaacattgggccattggtaaagaccatcatgacaagatgtatacagtgtact
cgctgcatcaggtttgcaagtgagattgcaggagtagatgatttgggaacaacaggcaga
ggaaatgatatgcaagttggcacatacattgaaaagatgttcatgtctgaactctctggg
aatatcattgatatctgccctgtaggtgcgctaacctctaagccctatgcctttactgcc
cggccttgggaaacaagaaagacagaatccattgatgtaatggatgcagttggaagtaat
attgtggttagcacaagaactggagaagtgatgaggattttgccacgtatgcatgaggac
atcaatgaagaatggatctctgataaaaccagatttgcctatgatgggctaaaacgtcaa
agacttaccgagccgatgatcagaaatgaaaaagggcttttaacctatacttcttgggag
gatgcactctctcgtgtagctggaatgttgcagagttttcaaggcaaagatgtggcagca
attgcaggtggcttggtggatgctgaagccctagtagctctcaaagatttgcttaataga
gtggactctgacaccttatgcactgaagaggtcttccccactgcaggagctggcacagat
ttgcgttccaattatcttcttaatactacaattgctggtgtggaagaggcagatgttgta
cttctggttggtacaaatccacgttttgaggcaccactgtttaatgctagaattcgaaag
agctggctgcataatgacttaaaagtggcccttataggcagtccagtggacctcacttac
agctatgaccacctgggagactcccccaaaattcttcaagacattgcttcgggaagtcat
ccatttagccaggtcctaaaggaagctaaaaaaccaatggtggttttaggcagttctgca
ctccaaagaaatgatggagcagcaattcttgcagctgtctctagcattgcacaaaagatt
cggatgactagtggtgttactggcgattggaaagttatgaatatccttcataggattgca
agtcaagtagctgctttggaccttggctataaacctggggtggaagcaattcggaagaac
cctcccaaagtgctgtttctcctgggagcagatggaggttgtatcacacgacaggatttg
ccaaaggattgtttcattatttatcaaggacatcatggtgatgttggggctcccatagct
gatgttattctcccaggagctgcttacacagagaagtctgctacatatgtcaatactgag
ggtagagctcagcagactaaggtagcagtgacacctcctggcttggcaagagaagactgg
aaaattataagagcactctctgagattgctggaataactcttccatatgatactctggat
caagtaaggaacagattggaagaagtctctcctaatcttgttcgatatgatgatgtcgaa
ggggctaattacttccagcaagcaaatgagctctcaaagctagtgaaccagcagcttctt
gctgacccacttgttccacctcagctaactataaaagacttctacatgacagattcaatt
agcagagcctcacagacaatggccaaatgtgtcaaagctgtcacagagggtgcccaggca
gtagaggaaccatccgtatgctga
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