Roseiflexus castenholzii: Rcas_1100
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Entry
Rcas_1100 CDS
T00585
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rca
Roseiflexus castenholzii
Pathway
rca00300
Lysine biosynthesis
rca00550
Peptidoglycan biosynthesis
rca01100
Metabolic pathways
rca01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rca00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Rcas_1100
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Rcas_1100
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Rcas_1100
Enzymes [BR:
rca01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Rcas_1100
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABU57199
UniProt:
A7NI99
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Position
complement(1423980..1425437)
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AA seq
485 aa
AA seq
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MLRLDEVLPGVQEEVNRRIHALPPALMQVAFSEAVIDSRLATSECLFVALRGERVDGHEF
LADAAARGARGALVRRSKVSSLTLERPYVVIDPVTGEGLERATPDTMLLIAVDDPQAALN
RLAAYHRGMYNPVVIGITGSVGKTSTKEVTAGVLQRSFRTLKSPRSYNSEATLPIVLLKL
TADHQVAVLEMGMYGPGEIAHLAALARPRLGIVTNVGPSHLERMGSIEAIQRAKSELPQA
LPEDGFAILNIDDPRVRAMAEVTRARPFFYGLDPAADLWADAIESRGLQGVSFRVHYQGD
GLHLTLPLLGRHSVHTALAAASAGLLLGMEWEAIIAGLRSEGAQLRLLAVPGINQTTLID
DTYNASPASMQAALNLLAELDGRRIAILGDMLELGSIEEEAHRMVGARAAEVAQILIAVG
QRARWIANEAQQAGLPADQVYAVDDNDAAAHLARNLLAPGDFVLIKGSRGMFMETIVSQL
QAHRP
NT seq
1458 nt
NT seq
+upstream
nt +downstream
nt
gtgttgcgactggacgaagtgctgcccggcgtgcaggaggaggtcaatcggcgcatccat
gcgctgcctcccgcgttgatgcaggtcgcctttagcgaagcagtaatcgattcgcgtctg
gcgacgtcggagtgcctgtttgtcgcattgcgcggcgaacgggtcgatggccacgaattt
ctggcggacgcggcggcgcgtggcgcgcgcggcgctttagtgcgccgcagcaaagtgtcg
agcctgacgctcgaacgcccttatgtggtgatcgatccggttaccggtgagggtctcgaa
cgggcgacgcccgacacgatgctgttgatcgctgtcgatgatccgcaggcggcgctgaac
cggctggccgcctatcaccgggggatgtacaaccccgtcgtgatcggcatcaccgggagc
gtgggcaaaacctcgacgaaagaggtgaccgccggcgttcttcagcgcagctttcgcacc
ttaaaaagcccaagaagttacaacagcgaggcgacattgcccatcgtgctgcttaaactt
accgccgaccatcaggtggcagtgctcgagatgggtatgtacgggccgggcgagatcgcg
catcttgcggctctcgcccgaccacgcctcggcatcgtcacgaatgtgggaccatcgcac
cttgagcgtatgggaagcatcgaagccattcagcgcgccaaaagcgaactgccgcaggcg
ttgccggaggatgggttcgccatcctcaacatcgacgatccgcgtgtgcgtgcgatggcg
gaggtgacgcgcgcccgaccgtttttctacggtctcgacccggcagccgacctgtgggcg
gacgcgatcgagagccgcggtttgcagggcgtcagttttcgggtgcattatcagggggat
ggtttgcatctgacgctgccgttgttggggcggcatagcgtgcatacagcgctcgcggct
gcttccgccgggttgttgcttggcatggaatgggaagcgatcatcgccgggttgcgtagc
gaaggcgcccaactcaggctactggcagttccgggcatcaaccagacgacgctgatcgac
gacacgtacaacgcctcgcctgcctcgatgcaggcagcgctcaaccttctggcagaactc
gatggtcggcggatcgccatcctgggcgatatgctggagttggggagcatcgaggaagag
gcgcaccgcatggtcggggcgcgggcggcggaagtggcgcagattctgatcgctgtcggg
cagcgcgcgcgctggattgccaatgaggcgcagcaggcgggattgcccgctgatcaggtg
tacgcggttgacgacaatgatgcagcggcgcacctggcgcgcaacctgcttgcacctggc
gactttgtgttgatcaaagggtcgcgcggcatgtttatggaaacgattgtgtcacagttg
caggcacatcgtccataa
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