Rhodococcus coprophilus: NCTC10994_00046
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Entry
NCTC10994_00046 CDS
T06666
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide-d-alanyl-d-alanine ligase murf
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rcr
Rhodococcus coprophilus
Pathway
rcr00300
Lysine biosynthesis
rcr00550
Peptidoglycan biosynthesis
rcr01100
Metabolic pathways
rcr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rcr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCTC10994_00046 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCTC10994_00046 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCTC10994_00046 (murF)
Enzymes [BR:
rcr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NCTC10994_00046 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
SQI28302
UniProt:
A0A2X4U244
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All DBs
Position
1:47654..49183
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AA seq
509 aa
AA seq
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MIPMTLERIAEVVGGTLHDADDPSVEVTGTVEFDSRKIGPGGLFLALPGARSDGHDHAAA
AIEAGAVAVLAARPVGVPAIVVPTPTPSATNALALEHDTDGSGAAVLAALAALARSVVDT
LTERGLTVVGVTGSAGKTSTKDLLAAVLEPLGPVVAPPGSFNNELGHPWTALRATEDTRF
LVLEMSARGRGHIAALAAIAPPKIGVVLNVGTAHLGEFGSQEVIAQTKGELVEALPDASE
GGVAVLNADDLLVAKMAARTGARVVWVGSGESADIRAEEVHLDDEARASFTAVFRDGADE
RRVPVTLAVHGEHQVGNALSALAVAVECGATPEQAAAALAAAAPVSAHRMAVRTRADGVT
VIDDAYNANPDSMRAGIKALVTMARSGGERRRTFAVLGEMAELGDDSVIEHDAIGRLAVR
VDVSRVIAVGASRQVRGLYQGAVMEGSWGEEACHVPDADAAIALLREELQPGDIVLVKAS
QSVGLWSVADAVLADRGENTAATGTEDAR
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgatgacactcgaacgcatcgcggaggtggtcgggggcaccctgcacgacgcc
gacgatccctctgtagaggtgacgggaaccgtcgaattcgactcccgcaagatcgggccc
ggaggactcttcctcgcgctgcccggcgcccgttcggacgggcacgaccacgcggccgcc
gccatcgaggccggcgcggtcgcggtgctcgcggcacgtccggtcggcgttcccgcgatc
gtggtaccgacgcccaccccgagtgccacgaacgcgcttgcactcgaacacgacaccgac
ggttccggtgccgcggtgcttgcagcgctcgccgcgctggcccgttcggtggtcgacacg
ctcaccgaacgcggactcacggtcgtcggcgtcacgggatctgccggtaagacctcgacg
aaggacctgctcgcagcggttctcgagccgctcggaccggttgtcgcgccgccggggtcg
ttcaacaacgaactcgggcacccgtggaccgcgctgcgcgccaccgaggacacccggttc
ctcgtcctcgagatgtcggcacgcggccgcggccacatcgccgcgctcgcggctatcgcg
ccccccaagatcggcgtggtgctcaacgtcggcaccgctcacctcggggagttcgggtcg
caggaagtcatcgcccagaccaagggcgaactggtcgaggcattgcccgacgcctcggag
ggtggcgtcgcggtgctcaatgccgacgatctgctcgtggcgaagatggcggcacgcacc
ggcgcgcgcgtggtgtgggtcggtagcggagagtcggccgacatccgcgcggaggaagtg
cacctcgacgacgaagcgcgtgcctcgttcaccgcggtgttccgcgacggcgccgacgag
cgccgcgtcccggtgacgctggccgtgcacggtgagcaccaggtcggcaacgctctgtcg
gcgctcgccgtcgccgtcgagtgcggcgcgacccccgagcaggcggccgctgccctcgct
gccgcagcgcccgtatcggcgcaccgcatggctgtgcgcacccgcgccgacggagtcacg
gtcatcgacgacgcgtacaacgccaacccggattcgatgcgcgcgggcatcaaggcactc
gtcacgatggcgcgctcgggaggcgaacgccggcgcaccttcgccgtactgggggagatg
gcagaactcggagacgactccgtgatcgagcacgacgcgatcggccggctcgccgtgcga
gtcgatgtctcccgcgtcatcgcggtcggagcgtcgaggcaggtgcgcgggctgtaccag
ggcgccgtgatggaaggatcctggggcgaggaggcctgccacgtgcccgacgcggacgcc
gcgatcgcattgcttcgtgaggaattgcagccgggcgacatcgtgctcgtcaaggcatca
caatcggtcggactgtggtcggtggccgacgccgtcctcgccgatcgcggtgagaacacc
gctgctacggggacggaggacgcccggtga
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