Ricinus communis (castor bean): 8277291 Help Entry 8277291           CDS       T01087                                  Name (RefSeq) auxin transport protein BIG   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism rcu  Ricinus communis (castor bean) Brite KEGG Orthology (KO) [BR:rcu00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:rcu04121]     8277291 Enzymes [BR:rcu01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      8277291 Ubiquitin system [BR:rcu04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     8277291 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UbLigase_R4 UBR4 ZZ Motif Other DBs NCBI-GeneID:  8277291 NCBI-ProteinID:  XP_048230333 LinkDB All DBs Position 5:10062541..10083764 Genome browser AA seq 5112 aa AA seqDB search MAEDKQQHLIKLYQSLFEEKLPSTDLFLRLRSDNSTKHGLYLFYLILKRSVSPREHHDHD RGIQKLGFQLWTDSQIQSVTSLGLAVVSACRSLSVEQVEPIVVAVVQQLLEFAVCYLEKS DCIGNVDFTTAQGNVILLLELALVDGIDKLSDPSQFCSVNCLLELLPKDSDDHCSIELEN HINCRLQGASCSKGENAVDLLMTLASESIQPELQALGFHGANQDVNNLIFLSQHWAVVHA DCVCRLILCCKQLIDLPYMHDEKVEVSDYFRRLSFGLRILKLLRTLIKDIPYVGYDASLL QAVASCVDVLPCLFRIRFEFANNHAYVEGSLEGLILLLLEEFLLFVRVAFCNSNACQNIQ VCIVASVLDNLDSSIWRYNNPATNSQPPLIYFPRSVLYILKRIQDLKRQTFQALDMKGFD TDLIGSSADLQDIYPSCHVHSMEVPLLKRFKHEDLLKIIFAPSTQWMDNLMHLLFFLHRE GLKIRPKVDRSLSNCSKVNPSEVENAVCHEDEALFGNLFYEGSRSVGSTDGFEQPPASVN SCSSNCNLPIQAASELLNFLKENVFSHEWSPPLFEDACKRLKEDHIDILLSVLSSQGFRL EDKSSDRCSASHEERKTGHINGICFELLLNLLTSCALPDNLEEYLIEQILNVEDDTFVYN DQTLTLLSHTLSSRVGLAGSQLRTKLFKGYVGFIVDKAKAVCSNCPSIKEVVGTLPSLFH IEILVMAFHLSSEQEKAALANLIFSSIRAVDAPSSGFSNTQLSCWALVVSRLILVLRHML FYPHNCPSSLLLDLRSKLREAPVCGSILPHSVNEQMSSWAFIAAKTVMGGCIEAEPTISA LINQLYDISALPPSLCRDELAVESLCLSWNDLCAALSWILGLWTGRKALSVADLIVERYM FSLCLDIPISSSTSDHQLSIWSETESMGISNMVNFFHFSHSLVAHTDDIGKGMNLPNVVL GVLQHLSELYMPEDIEELGLDFLRNGFWLSMVISLLNVGICHYCIKNSIPGACPSWIENT ARDNAYITIAEGLTSSLNESGQVLLLLGFLSSLLTRYIQAYQKAFLATVADGQCTAVGFS SLLLLKHSSFDNCLQDGLLKKSGISSYHLESFSDILSKWDAVIDKRAPSVRCKVFCESML HGFPSHLQTPSAILLSSILSIRGIVFVLDGLFRIEDMKMNIFKERKVLCQILNSVMTIKF DRIFESIQGKCVAIVRNLSVGFELPDYSDLFLLKHMEGFLREINASEECDSNSLEWVINK IIDTADSLRKDTLKSAIFKFYLGAEDVPEPLKEFYGLQRGDLLVLIDSLDKCSSESANAK VLNFFIDLLSGEYCPYLKQKIQKKLFEMDLLHLSKWLEKRLLGSVVEASGGASYAKENSV SLRETTMSFISTLVFLPSESHLTELNHHLFEALLASLDTAFLLFDVHIAKLYFHFLVQLS RGEYLMKLLLKKTIMLMEKLAGDERLLPGLRFLFSFLGNISSDCGSCKSTSEKLQGKSLS GSSLGMGSVALKPVGSRKNSDSIVISANQEGGPTALECDAISVDEDEDDGTSDGDVASMD KDEEEDTNSERALASKVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCAKVCHRGHRV VYSRSSRFFCDCGAGGVRGSNCQCLKPRKFTGNDSAPIRSASNFQSFLSFTDDADQLPDS DSDLDEDLSLDTDSSLRLSIPRELQDGIKALLGELDIEGCVLQLCSSLLPSITSKRESNI SKDKKIVLGKDKVLSYSVELLQLKKAYKGGSLDLKIKADYPNAKELRTHLASGSLVKSLL SVSNRGRLAVGEGDKVAVFDVGQLIGQATIAPVTADKTNVKPLSRNVVRFEIVHLVFNSV VENYLAIAGYEDCQVLTLNPRGEVTDRLPIELALQGAYIRRIDWVPGSQVKLMVVTNRFI KIYDLSQDNISPLHYFTLPDDMIVDATLLVASQGRMFLIVLSEQGSLFRLELSVQGNVGA TPLKEIIQIKDREMNAKGSSLYFSATYKLLIISYQDGTTLMGRLSSDATSLTDMSFVYED EQDGKMHSAGLHRWRELLIGSGLFVCFSSVKSNAALAVSMGPQELHAQSMRHAVSSTSHL VGLTAYKPLSKDKVHCLVLHDDGSLQIYSYIPAGSDASASLTADKVKKLGSGILNSKAYA GVKPEFPLDFFEKTVCITADVKLGGDAIRNGDSEAAKQSLASEDGFLESATPAGFKISAS NSNPDIVMVGFRVHVGNSSANHIPSDITIFQRVIKLDEGMRSWYDIPFTVAESLLADEEF VISVGPTFNGTALPRIDSLEIYGRAKDEFGWKEKMDDMEAHVLGSNSLLGGSGKKCRSLQ SASIQEQVVADGLKLLSKLYSLCRSQDEDAKTDPSELECKLLLETIFESDREPLLQAAAC HVLQSVFPKKDIYYQVKDSMRLHGVVKSTSMLSSRLGVGGTTGGWIVAEFTAQMRAVSKI ALHRRSNLALFLELNGSEVVDGLMQVLWGILEFEQPDTQTMNNIVIASVELIYCYAECLA LHGKDTAGRSVAPAVALLKKLLFSPSEAVQTSSSLAIASRLLQVPFPKQTMLATDDAADS GISAAGAAETTGGNTQVLIEEDSITSSVQYCCDGCSTVPILRRRWHCTVCPDFDLCEACY QVLDADRLPPPHSRDHPMTAIPIEVESLGGDGNEIHFTTDDANGSNLMPITADVSMQNST PSIHVLEPNESGDFAASVTDAVSISASKRAVNSLLLSELLEHLKGWMQTTSGVRAIPVMQ LFYRLSSAVGGPFIDSSKPEASDLEKLIRWFLDEIDLNRPFVAKNRNSFGEVAILLFMFF TLMLRNWHQPGGDGSILKSSGSTDSHDKNVIQATSIASHSSLDGQEKSDFTSQLLRACST LRNQAFVNYLMDILQQLVNLFKSPTTSFETAHGLHAGSGCGALLTVRRDLPAGNFSPFFS DSYAKAHRTDIFMDYHRLLLENAFRLVYTLVRPEKQDKTGEKEKVYKISSGKDLKLEGYQ DVLCSYINNPHTTFVRRYARRLFLHLCGSKTHYYSVRDSWQFSTEMKKLYKHINKSGGLQ NPVPYERSVKIVKCLSTMAEVAAARPRNWQKYCLRHGDVLPFLMNALFYFGEESVFQTLK LLNLAFYSGKDMTHSLQKLEAGDSGTSSNKLGGQSPDSKKKKKGEEGGTDSGLEKSYLDM ETAVDIFADKGGDVLRQFVDCFLLEWNSSSVRMEAKCVLYGAWHHGKHSFKETMLMALLH KVKNLPMYGQNIVEFTELVNWLLGKVPDNSLKQQSTEIVDRCLTPDVIRCIFETLHSQNE LIANHPNSRIYSTLSGLVEFDGYYLESEPCVACSSPEVPYSKMKLESLKSETKFTDNRII VKCTGSYTIQTVTMNVHDARKSKSVKVFNLYYNNRPVADLSELKNNWSLWKRAKSCHLAF NQTELKVEFPIPITACNFMIELDSFYENLQALSLEPLQCPRCSRPVTDKHGICSNCHENA YQCRQCRNINYENLDSFLCNECGYSKYGRFEFNFMAKPSFTFDNMENDDDMKRGLAAIES ESENAHRRYQQLLGFKKPLLKIVSSIGENEMDSQQKDSVQQMMVSLPGPSCKINRKIALL GVLYGEKCKAAFDSVSKSVQTLQGLRRVLMSYLHHKHSDDAIAASRFVVSRSPNNCYGCA TTFVTQCLEMLQVLSKHPKSKKQLVAAGILSELFENNIHQGPKTARVQARTVLCSFSEGD INAVTELNNLIQKKVMYCLEHHRSMDTAVATREELLLLSEVCSLADEFWESRLRVVFQLL FSSIKLGAKHPAIAEHIILPCLRIISQACTPPKPDSVDKDQGIGKPPPAAQIKDENNSNT SGSLSGVVSGSKSGSDGLEKNWDASQRTQDIQLLSYSEWEKGASYLDFVRRQYKVSQAVK GAGQRSRPQRHEYLALKYALRWRRRASKTSKGDLSTFELGSWVTELVLSACSQSIRSEMC MLISLLCAQSSSRRFRLLNLLMALLPSTLAAGESAAEYFELLFKMIDSEDARLFLTVRGC LTTICKLITQEIGNVESLERSLHIDISQGFILHKLIELLGKFLEVPNIRSRFMRDNLLSD ILEALIVIRGVIVQKTKLISDCNRLLNDLLDSLLVESSENKRQFIRACISGLQIHGKERK GRTCLFILEQLCNLICPSKPESVYLLILNKAHTQEEFIRGSMTKSPYSSSEIGPLMRDVK NKICHQLDLLGLLEDDYGMELLVAGNIISLDLSIAQVYEQVWKKSNNQSSNAMANSTLLS SSGMPSARDCPPMTVTYRLQGLDGEATEPMIKELEEDREESQDPEVEFAISGAVREYGGL EILLGMIQRLRDDFKSNQEQLVAVLNLLMHCCKIRENRRALLRLGALGLLLETARRAFSV DAMEPAEGILLIVESLTLEANESDNISVAHNALTVTSEETGTGEQAKKIVLMFLERLCHP SGLKKSNKQQRNTEMVARILPYLTYGEPAAMEALIQHFNPYLQDWREFDRLQKQHQENPK DENIAHKAAEQRFTVENFVLVSESLKTSSCGERLKDIIMEKGIIDVAVRHLRESFAVAGQ AGFKSREEWSSGLKLPSVPHLLSMLRGLSMGHLATQNCIDQGGILPLLHTLEGVSGENEI GARAENLLDTLSNKEGKGDGFLEEKVRKLRHATRDEMRQRALRKREELLQGLGMRRELAS DGGERIVVAWPVLEGLEDVEEEEDGLACMVCREGYSLRPTDLLGVYSYSKRVNLGVGTSG SARGECVYTTVSYFNIIHFQCHQEAKRADAALRNPKKEWEGATLRNNESLCNSLFPVRGP SVPLAQYIRYIDQYWDNLNALGRADGSRLRLLTYDIVLMLARFATGASFSAESRGGGRES NSRFLPFMIQMARHLLEQGSPSQLRSMAKTVSSYIASSSLDSRPSLGIQPAPGTEETVQF MMVNSLLSESYESWLQHRRSFLQRGIYHAYMQHTHGRSTARASSTSTGIGRMESGSISRS PMSETGGADELLSIVRPMLVYTGLIEQLQRFFKVKKSPNTPPVKAEGSSARSEGEDENGN LEGWEVTMKERLLNVREMVGFSKELLSWLDEMNSSTDLQEAFDIIGVLADVLSGGTSQCE DFVHAAISGGIS NT seq 15339 nt NT seq  +upstreamnt  +downstreamnt atggcagaagacaaacagcaacacttaattaaactctatcaatctctctttgaagagaaa cttccttctaccgatctcttcctcagactccgttctgataattcaaccaaacatggcctc tacctcttctacctcatccttaaacgcagcgtctcacctcgtgaacatcatgatcatgat cgtggtattcaaaagttagggttccaattatggaccgattcgcagattcagtctgttact tcgttaggtctcgctgttgtctctgcttgcagatctctgtcagtggagcaagtcgagccg atagttgtggcagtggtgcaacagttgttagagtttgctgtttgttatctagagaaatca gactgtattggcaatgtcgatttcactactgcacagggaaatgtgatactacttttggaa ttggcattggttgatggaattgataaattatcagatccttcccagttttgctctgtaaat tgtcttctagaactattgccgaaggattctgatgatcattgcagtattgagttggaaaac cacataaattgtaggcttcaaggtgccagttgctcaaagggagagaatgcagttgatcta ctgatgacacttgcatctgaaagcattcaacctgagttgcaagctcttggcttccatgga gccaaccaagatgtgaacaacttgatttttctgtctcagcactgggctgttgtccatgct gattgtgtttgccgtctgatattatgctgcaaacaactaattgatttgccatatatgcat gatgagaaagtggaagtttcagattatttcaggagattgtcctttgggttgaggattttg aagttactcaggactctcataaaggacattccatatgttggatatgatgcctcactgttg caagcagttgcttcatgtgtagatgtgctaccttgcttgtttagaattcgctttgaattt gcaaacaaccatgcttatgttgagggtagtttggagggtctcatattgttgctgttggaa gagtttcttctttttgtccgagttgctttctgcaatagtaatgcatgtcagaatatccaa gtatgcatagttgcttctgtattggataacttagattcttctatatggagatacaacaac cctgccactaattcacagcctcctctaatatactttccacgctctgttctttacatcttg aaacgcatacaggatctcaaaaggcaaacttttcaggctcttgacatgaagggctttgat acagatcttattggcagctctgctgatttgcaagatatttacccgtcatgccatgtacat tctatggaggttcctttgcttaaaaggtttaaacatgaggatctgttgaaaattatattt gctccttcaacccagtggatggacaatctgatgcatcttcttttcttccttcatcgtgaa ggacttaaaataaggcctaaagtagataggtctctttctaattgttcgaaagttaaccct tcagaagtggaaaatgcagtttgtcatgaagatgaagccctctttggaaaccttttttat gaaggtagtcgctcagtgggatctactgatggatttgagcaaccaccagctagtgtcaat tcatgctctagcaattgtaatttgccaatacaagctgcatctgagttattgaattttctg aaagagaatgtcttttcccatgaatggtctccccctctttttgaggatgcctgcaaaagg ctaaaagaggaccacattgatatattgctttctgtgcttagttctcagggctttcgttta gaggataagtcttctgatagatgttctgcttctcatgaagagagaaagactgggcacatc aatggaatttgcttcgagttgctgcttaaccttcttactagctgtgctttgcctgataat cttgaagagtaccttattgagcaaattttgaatgttgaagatgatacctttgtttacaat gatcagaccctaaccttgctatctcacactctctcttctagggtgggtttggctggtagc cagttaagaaccaaattgtttaaaggatatgtgggtttcattgttgataaggctaaagct gtttgttcaaattgccctagtattaaggaagttgttgggactctcccatcgctatttcac attgagattcttgtaatggcattccacttatcatctgaacaagagaaggcagcacttgca aacttaatattttcttccatccgagcagttgatgctccatcttctggcttttctaacact caattgtcatgttgggctttagtagtctcaaggttgatcttagtacttcgtcatatgctg ttttatcctcataattgtccttcatcgctgctgctagatttgaggtcaaaactgagggaa gctccggtttgtggttcaattctgcctcatagtgtaaatgagcagatgtcttcttgggca tttattgcagcaaaaactgtaatgggtggatgcattgaagctgagccaaccatcagtgcc ttgattaatcaactatatgacatttcagctcttcctccttcactttgtagagatgaattg gctgttgaatccttatgcttgagctggaatgatttatgtgcagccctctcgtggattctg gggctctggacgggtagaaaagctttgtcagtagcagaccttatagttgaaagatatatg ttctcgctttgtttggatattcctatttcgagctctacatcagaccaccagctttcaatc tggtcagagacagagtcaatgggcatatctaatatggtaaatttctttcacttcagccat tcacttgtcgcccacactgatgatattggcaagggcatgaaccttccaaatgttgttcta ggtgttttacagcacttgtctgagctgtacatgccagaagatattgaagaactaggtttg gatttcttgaggaatgggttttggttgtctatggtaatctccttattaaatgttggtatt tgccattattgcatcaaaaatagtatccctggagcgtgtccgtcctggatagaaaataca gctagggataatgcatacatcactattgctgaaggcttgacttcgagcttaaatgagtct ggtcaagttttattgctgctgggattcttgtcgtctttgttgaccagatatatacaggca tatcaaaaggctttccttgctactgttgctgatggccagtgcactgctgttgggttttca tctctgttacttctcaagcactccagttttgataactgccttcaggatgggttacttaag aagagtggcatcagttcttaccacctggagtctttttctgatatattatcaaagtgggat gctgtaattgacaaaagagctcctagtgttcgatgcaaagtgttttgtgaaagtatgttg catggttttccatctcatcttcaaactccaagtgcaatccttctgtcttctattcttagc ataagaggcatagttttcgttttagatggtttgttcagaatagaagatatgaaaatgaat attttcaaagagaggaaggtactttgccagattctgaattcggtgatgaccatcaaattt gacagaatctttgaaagcattcaaggaaaatgtgtagccattgttagaaacctgagtgtt ggctttgaactgccagattatagtgatctctttctattgaagcacatggaagggttttta agggaaattaatgccagtgaagagtgtgatagcaattcccttgaatgggtaatcaacaag ataattgatactgcagatagcctcaggaaagacacattgaaatctgcaatcttcaaattt tatcttggcgcagaagatgtgcctgaaccactcaaggagttctatgggttgcaacgtggt gatctgttagttctaattgattccctggacaaatgttcttctgaatctgcaaatgcaaag gtacttaatttcttcattgatctcttatcaggagagtattgtccatatctcaaacagaag attcagaaaaaattgtttgagatggatctgcttcatctgtccaaatggttggagaaacgg ttgttaggctctgtagtggaagcttcaggtggtgccagctatgcaaaggagaattctgtt tctcttagagaaacaactatgagttttatttcaactcttgtattcttaccttctgaatca catttgacagaactgaaccatcatttgtttgaagctttgctggcttcacttgacactgca tttttgctatttgatgtccatattgctaaattgtacttccattttcttgttcaactttct agaggggaatatttaatgaaattgcttttgaagaaaactataatgttgatggagaagctg gccggagatgaacgtttgcttccagggctgagatttctctttagctttcttggaaatatc tctagtgattgtgggtcttgtaagagcacttccgaaaagttgcaggggaagtctttatct ggaagtagtctcggcatgggttctgttgctttaaagccagtaggatctaggaagaattct gactctatcgttatctctgcaaaccaagaagggggacccacagcccttgagtgtgatgca atttctgtggatgaagatgaggatgatgggacatctgatggcgatgtagctagcatggat aaggatgaggaggaagataccaatagtgaaagggcacttgcctcaaaagtttgcacattt acatccagtggcagcaattttatggaacagcactggtacttttgttatacttgtgatctg acagtatcaaaaggttgttgctctgtgtgcgcaaaagtttgtcatcgtggacatcgtgtt gtttattctcgttccagtcggtttttttgtgactgcggagctggtggtgtgaggggtagc aattgccaatgcttgaagcctcgaaaattcactggaaatgacagtgcgcccatccgtagt gctagtaattttcagtctttcttatccttcacagatgatgctgatcagttgccagacagt gattctgatctagatgaggatttgtccttagatacagatagctcccttaggttatcaatt cctagagagcttcaagatggcatcaaagcattgcttggagaacttgacattgaggggtgc gtgcttcaactttgctcctcattattgccatctataacaagcaaaagagaatctaatatt tccaaagataagaaaatagttctgggcaaagataaagtgctttcatacagtgttgagctg ttgcagttgaagaaggcatataaaggtgggtctttagatctgaaaataaaggctgattat ccaaatgctaaggagcttagaacacatttggccagtggttctctagtcaaatccttgctt agtgtcagtaatcgaggtcgacttgctgtgggagaaggtgacaaagttgctgtatttgat gttgggcagttaattggacaagccactatagcaccagtgacggcagacaagaccaatgtt aagcccctctcaagaaatgttgttcgctttgaaattgttcatcttgtttttaattcagtc gtggaaaattatcttgctatagctggctatgaagattgccaagtcctgactttaaatcct cgtggtgaagtgactgatcgtcttcccattgaacttgctcttcaaggtgcatatatcaga cgaattgattgggttccaggttctcaggttaagttaatggtagtaactaacaggtttatc aaaatatatgatctatcccaggacaacatcagtcccttgcattacttcacattacccgat gacatgattgttgatgcgacacttcttgtggcttctcaggggagaatgtttcttattgtt ctttctgaacaagggagcttgttcaggttagaattatctgtgcagggtaatgttggggcc accccgttgaaggaaattattcagattaaggacagagaaatgaatgcaaaaggatcatct ttatatttctctgccacttacaaattgcttatcatttcctatcaagatggcactactttg atgggtcgattgagctccgatgcaacatctctaacagatatgtcatttgtatatgaagat gaacaagatggcaagatgcattcagctggtctacatcgttggagagagttgctgataggc agcggcttgtttgtttgcttctccagtgtgaaatcaaatgctgcacttgctgtgtccatg ggacctcaagaattacatgcacaaagcatgcggcatgctgtgagctcaacctctcattta gttgggttaactgcttacaagcctctctcaaaagacaaggtccactgtcttgttttacat gatgatggaagccttcagatatactcatacatcccagcaggatctgatgctagtgcaagt ttgactgctgataaagttaaaaaattggggtctggcatcctcaacagtaaagcgtatgct ggcgtcaaaccagagttccctctcgatttctttgagaaaacagtctgcattactgcagat gtaaaattgggtggtgatgccatcagaaatggtgattctgaagctgcaaagcagagcttg gcatctgaggatggctttctagaaagtgccacacccgcaggctttaagatatccgcctcc aattcaaatcctgacattgtcatggtggggtttcgtgtgcatgtgggcaacagttcagca aaccatataccttctgatattaccattttccagagggtaattaagctagatgagggcatg cgatcttggtatgatattccttttactgtagctgaatccctccttgctgatgaagaattt gtaatctctgttgggccaaccttcaatggaactgctcttcccagaattgattctcttgaa atatatggtcgagctaaagatgaatttggctggaaagagaaaatggatgatatggaagct catgtgcttggttccaattcattgcttggaggttctgggaaaaaatgccggtcgttgcag tctgcttctattcaggagcaggtggtagctgatggtctgaagctcttgtccaagctatat tcattatgtaggtcccaagatgaagatgcaaaaacggatccaagtgagcttgagtgtaag ctgctcttagaaacaatttttgaaagtgacagagagcccttgttacaggctgctgcttgt catgtattgcagtctgttttccccaaaaaagatatatattaccaggttaaagactctatg cgccttcatggggtggtcaaatcaacctctatgctatcttctaggctaggagttggagga actactggagggtggatagttgcagaatttactgctcagatgcgtgctgtatctaagatt gctttgcaccggcgttctaatttagccctttttctggagctgaatggttctgaagtggta gatggtctcatgcaagttctatggggaattttggagtttgaacaacctgacacccaaacg atgaacaacattgtcatagcctctgtggagcttatatattgttatgctgaatgtctggct ttacacggaaaggacacagcaggacgttctgttgctcctgctgttgcattattaaagaaa ctcctattctcccctagtgaggctgttcaaacatccagcagccttgctatagcatcaaga ttgcttcaggttccgttcccaaagcaaacaatgttagcaacagatgatgctgcagatagt ggtatctctgccgctggtgctgctgagacaactggtggaaatacacaagtcttgattgaa gaagattctattacctcttctgttcaatattgttgtgatggctgctccactgttcctata ctaaggcgaagatggcattgtactgtatgtcctgattttgacttgtgtgaggcttgttat caggtattagatgcagatcggcttcctccaccccattctagagatcatccaatgactgct attccaattgaagtggaatcattaggaggagatgggaatgaaattcacttcactactgat gatgccaatggttcaaacttgatgcctatcacagcggatgtcagcatgcagaactccact ccttcaattcatgtcttggaacccaatgaatctggagattttgctgcctcagtgactgat gcagtctctatttctgcctcaaaaagagctgtgaattccttgcttctctctgaacttctt gaacatttgaaaggatggatgcagacaacatctggtgttcgtgctatccctgtcatgcaa ctattctatagattatcgtctgctgtaggcggaccttttatagacagttccaaacccgag gcctcggatttagagaaactgattcggtggtttttggatgaaattgatctaaacagaccc tttgtagccaaaaaccgcaattcatttggggaagttgcaatccttctctttatgttcttc actttgatgcttcgaaactggcaccagccgggtggtgatggttctattctaaaatcaagt ggaagtacagactcgcatgataagaatgttattcaggccacttcaattgcttctcattct tccttggatggtcaagagaaaagtgactttacatctcaactccttcgagcctgcagtact ctcaggaaccaagcatttgttaattatctaatggatattctgcagcagttagtcaatctt tttaagtcccctacaactagttttgagaccgcgcatggtttgcatgctggttcaggatgt ggtgctctattaacagttaggagagatttaccagcgggcaatttctctccattcttttct gattcatatgcaaaagcccatcgaactgatatttttatggattaccataggcttttattg gagaatgctttccgactggtgtacactttggttagaccagaaaagcaggacaagactggg gagaaagagaaggtctacaagatttcatctggtaaggatttgaaactagagggatatcag gatgttctttgcagttacataaataatcctcatactacgtttgtaagaagatatgcaagg aggctgtttctgcatctttgtggaagtaaaactcactattatagtgttcgagattcctgg cagttctctactgaaatgaagaagctttacaagcacataaataaatctggtggtcttcaa aatcctgttccatatgagagaagtgtgaagatagtgaagtgcttgtctacaatggctgaa gttgctgcagcacggcctcgaaattggcagaaatactgcttgaggcatggagatgtgtta ccctttttgatgaatgcactgttctatttcggcgaagagtctgtttttcagactctcaaa cttctgaatttagccttttattcaggaaaggatatgacccactccttgcagaaacttgaa gctggagactccggaacaagctcaaacaaattggggggccagtctccggattcgaagaag aagaagaaaggtgaagagggggggactgactctggactggagaaatcttatttggatatg gagacagcagtggatatctttgctgacaagggtggtgatgttttgaggcaatttgttgac tgctttttactggaatggaattcaagctctgtgcgcatggaggctaagtgtgttctttat ggtgcatggcatcatggaaagcattcgttcaaggaaacaatgttaatggctctcttgcat aaagtgaaaaatctcccaatgtatggacagaacattgttgagttcactgaacttgtcaat tggttactgggtaaagtccctgataatagtttaaagcagcagagcactgaaattgtggat cgttgcttgactcctgatgtaattaggtgcatctttgagacactccattcacaaaatgag cttattgctaatcatccaaattctcgaatatatagtactttgagtggtcttgtggaattt gatggttattaccttgagagtgaaccttgtgttgcctgcagctctcctgaggtaccctat agcaagatgaagttggaaagcttgaagtctgagactaagtttacggacaatcgcatcata gtgaaatgtactggaagttacacaatacaaactgtgactatgaatgttcatgatgcacgc aaatccaaatctgtcaaagtcttcaacctgtattacaacaatcggcctgtagctgacttg tcagagttgaaaaataattggtctttgtggaagcgcgcaaagagttgtcatcttgcattc aaccagactgagctaaaagtggagtttcctattccaatcactgcctgtaacttcatgatt gaactggattctttctatgagaaccttcaggcactatctcttgaaccattgcagtgtcct cgttgcagtcgacctgtcaccgataagcatggaatttgcagcaattgccacgagaatgca tatcagtgcaggcaatgccgcaacataaactatgaaaatctggattcttttctgtgcaat gaatgtgggtacagcaaatatggccgttttgagtttaacttcatggcaaagcctagtttt acatttgataacatggagaatgatgatgatatgaagaggggtttggcagccatagagtca gaatcagaaaatgctcataggagataccagcaacttttgggcttcaaaaagcctcttctt aagattgtatcaagcattggagagaatgaaatggattcacagcagaaggactctgtccag caaatgatggtttctctgccaggaccttcgtgtaagataaaccgtaagattgctcttctt ggtgtcttgtatggtgaaaaatgcaaagctgcttttgattctgtcagcaaaagtgttcag acactgcagggccttcgtcgggttttgatgagttacttgcaccacaaacattcagatgat gcaattgcagcgtccagatttgtggtttccaggtctccaaataattgctatggctgtgca actacatttgtgacacaatgtttggagatgctacaggttctgtcaaaacatcctaagtca aagaaacaacttgttgcggctggcatcttatctgaactgtttgaaaataatattcatcaa ggtccaaaaacagctcgtgttcaagctaggacagtgctttgttctttctctgaaggtgat ataaatgcagttactgagttaaacaacttaatacagaagaaagtcatgtactgccttgaa catcatcgttctatggacactgcggttgccactcgtgaggagctattactgctttcagaa gtgtgttccttggctgatgagttctgggaatcaagattacgtgttgtttttcagctgtta ttttcgtccattaaattgggtgccaaacaccctgcaatagcagagcatattattctcccc tgtctgaggatcatatctcaggcatgcactcctccaaaaccagattcggtggacaaagat cagggtattggaaaacctcctcctgcagctcagatcaaggacgaaaacaactcaaatacc tctggatctttgagtggggtagtcagtggtagcaagtcaggatcagatggtttggagaaa aactgggacgcttctcaaaggactcaggatattcaattactaagttattcagagtgggag aagggagcatcatatcttgattttgttagaaggcagtataaagtgtctcaggcagtgaaa ggggcagggcagagatctcggccacagagacatgaatatctagctctcaaatatgcactt aggtggaggcggcgtgcttctaagacgtctaagggtgatttatccacatttgagcttggg tcttgggtgaccgaacttgttttgagtgcttgctcgcaatctatcaggtcagagatgtgc atgctgattagtttactttgtgctcagagttcatcaaggcggtttcggttgctaaactta ctgatggctttgctgccgtcaacccttgctgctggtgaaagtgcagcagaatactttgaa ttgttgttcaagatgatcgattcggaagatgcccgtctcttcttgactgtccgtggatgt ctaactacaatttgtaaactgattacccaagaaattggtaatgttgaatctttagaaagg agtctgcatattgacatttcacagggtttcattcttcacaagcttattgaactccttgga aagtttttggaggttcctaatatcagatccagatttatgcgagataatttgctatctgat atccttgaagctcttattgtgatccgtggcgtgatagtacaaaagacaaagttgatcagt gactgcaatcgccttctaaatgatcttttagatagtcttcttgttgagagcagtgaaaac aaacgacagtttatccgagcttgtatctctggtctacaaatccatggaaaggagagaaaa ggacgaacttgtttgtttatcctagagcagctttgcaatttgatctgcccatcaaaacca gagtctgtatatttgttgattcttaacaaggcgcacacacaggaagagtttatcagggga tcaatgactaagagtccatattccagttctgagattggtcctctgatgcgagatgttaag aataaaatttgccatcaattggatctgctaggccttcttgaagatgactatggcatggag ctgctggtagctgggaacatcatctctcttgatttgagcattgcgcaagtttatgagcaa gtctggaagaagtcgaataatcaatcgtcaaatgcaatggctaattctaccttgttatcc tcaagtggcatgccatcagcaagagattgcccacctatgacggtgacttacagacttcag ggattagatggagaagccactgaacctatgattaaagaactggaagaagatagggaagaa tcacaagatccagaggttgagtttgcaatatctggagcagttcgagagtatggtgggctt gaaattctactaggcatgatccagaggttgcgggatgatttcaagtccaaccaggagcag ttggttgcagttcttaatcttcttatgcattgctgcaaaataagagaaaacagacgggcc ctgttaaggcttggagctttaggtcttcttcttgaaacagcaaggcgtgccttctctgtg gatgccatggagccagcagaaggcattcttttgatcgttgagagcctcacattggaggca aatgaaagtgataatattagcgttgcacataatgcacttaccgtcactagtgaggaaaca ggaacaggagaacaggccaaaaaaatagttcttatgttcctggaaaggttgtgccaccct tcaggccttaaaaagtcaaacaaacagcaacggaacacagagatggttgcaagaatcttg ccatatctgacatatggtgaacctgctgcaatggaagctctcattcagcattttaaccca tatttgcaagactggagggaatttgaccgactgcagaaacaacatcaagagaacccgaaa gatgagaacattgctcacaaagcagctgagcagaggtttactgtggaaaattttgttcta gtatccgaatcactaaagacaagttcctgtggggaacggttgaaggacattatcatggag aaaggtatcatagatgttgctgtcagacacctgagggagagttttgcagttgcagggcag gctgggtttaagtcccgtgaagaatggtcatcaggtttgaaactgccatctgtcccgcat ttgttgtctatgctaaggggattgtcaatgggacacctggctactcaaaactgtattgat cagggcgggatcctacccttgctccatactctggaaggagtctctggagaaaacgagata ggtgctagagctgaaaatttgttagatactctatctaataaggagggtaaaggagatgga ttcttggaagagaaggtgcgcaagttgcggcatgccactagagatgagatgcggcagcga gcattaaggaaaagagaagagttacttcagggactcggaatgcggcgagaactggcatca gatggtggtgaaagaattgttgttgcttggccagtcttggaaggtttggaagatgtagag gaagaggaagatgggctggcatgcatggtttgccgtgagggctatagtttgaggcctact gacttacttggggtttactcctacagcaagagggtgaatctgggtgttggcacttcagga agtgctcgtggagagtgtgtttataccactgtcagttatttcaacattattcattttcag tgccatcaggaggccaaaagagcagatgcagctctgaggaatcctaagaaagaatgggaa ggtgctactctcagaaacaatgaatctctatgcaattccttattccccgtaagaggtcca tcggttccgctagcacagtacatccgctatatagatcagtactgggataacctcaatgct cttgggcgtgctgatgggagtcggctccggctgttgacttatgacattgttctgatgctg gctcgatttgcaacaggggcctcattcagtgcagaaagtagaggtggaggaagggaaagc aactctcgttttcttcctttcatgattcaaatggcccgtcaccttcttgaacagggaagc ccatcccagctcagaagcatggccaagactgtgtcttcatatatagcatcatcatcgttg gattctagaccttctcttggaatacagcctgctccaggaactgaagaaactgtgcagttt atgatggtgaattcacttctctcagagtcctatgagtcttggttgcaacaccgccggtcc ttcttgcagagaggaatataccatgcatacatgcagcacactcacggccggtcaactgct agggcatcatcaacttctacaggcataggcagaatggagtcgggaagcatcagcagaagt cccatgtcagaaactgggggtgctgatgagctgctgtctattgtacggcctatgcttgtt tacacaggcttgatcgagcagctgcagcgcttttttaaggtgaaaaaatcacccaacacg ccacctgttaaagcagaaggaagttctgctagatcagaaggggaagatgagaatgggaat ctggaaggatgggaggtgacaatgaaggaacgactgttaaatgtgagagaaatggtagga ttctcgaaggagttgttgtcgtggcttgatgagatgaattcctccactgatttgcaggag gcctttgacattattggtgttctagctgatgtgttgtctggtgggacttcacagtgtgag gacttcgtccatgctgcgatcagtggagggataagctaa

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