Rothia dentocariosa: HMPREF0733_11667
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Entry
HMPREF0733_11667 CDS
T01343
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rdn
Rothia dentocariosa
Pathway
rdn00300
Lysine biosynthesis
rdn00550
Peptidoglycan biosynthesis
rdn01100
Metabolic pathways
rdn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rdn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HMPREF0733_11667 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HMPREF0733_11667 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HMPREF0733_11667 (murF)
Enzymes [BR:
rdn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HMPREF0733_11667 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
CbiA
Motif
Other DBs
NCBI-ProteinID:
ADP41124
UniProt:
E3H0V7
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Position
1845255..1846862
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AA seq
535 aa
AA seq
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MIKLSAAEIITATGGSPLGLAGRESELGATFATTDSREVIPGTLFVAKPGEVTDGHNFVS
GAFDKGAVLALVERPVKDERGILYPSIQVDDVVLAMGKIAQYAVEKMRSLGDLTVIGITG
SAGKTTTKDLLAAILSSQGETIAPVGSYNGEVGVPLTVFRADESTRYLVIEMGADHVGNI
EYLANIVHPDHGVILKVGTAHAGEFGGVDNIERTKGELAEGIRTGGTLILNADDERVARM
SARASAPVTYFGVGEKPQYERYTAALGLHTNDAGCPEFTLRLPDASEYEISSKLIGEHHV
CNILAAATVAYNAGVPGDAIAHALNNTGALSKWRMARTDRADGVTVINDAYNANPESMTA
ALRTLAQLGRGAKPRRTWAVLGAMLELGEASLEEHDRLGRLVVRMNISKLIAVGNEAKPA
YNAAHLEGSWGNEATWVETPQEALNILRAELRSGDIVLFKSSNGAKLGSLGDEVAFCTET
FGEAQEQAPAWLSAGDFVEVTDLTGAALSTVSAGSSAAQTSTTALDRSHLHEGTH
NT seq
1608 nt
NT seq
+upstream
nt +downstream
nt
atgattaagctttccgccgccgaaattattacggcaacaggcggctcaccgctcggctta
gccgggcgtgagagcgagctaggtgctaccttcgcgaccaccgattcgcgtgaggttata
ccaggcaccctatttgttgctaagccaggtgaggtgaccgacggacacaacttcgtgtca
ggagccttcgacaaaggtgctgtcttagcgcttgtcgaacgccctgttaaagatgagcgg
ggtattctgtaccccagcatccaggttgatgatgtggttctcgccatgggtaagatcgca
cagtacgctgttgaaaagatgcggtctctaggcgatcttacggttatcggtattaccggt
tctgcggggaagaccaccacaaaagatttattagcagcgatcctaagttctcagggcgaa
actatagcccctgtaggttcgtacaacggcgaagttggcgtacctttgactgtattccgc
gctgacgaaagtactcgctaccttgtgattgagatgggtgccgatcatgtggggaatatc
gaatacctggcaaatattgtgcaccctgaccatggtgtgatccttaaagttggcaccgca
catgctggcgagtttggcggggtcgacaacatcgaacgtactaaaggggagcttgccgaa
ggtattcgtactggcggaaccttgatcctcaatgctgatgatgagcgtgttgcacgcatg
tcagctcgtgcaagtgcgccggtaacctactttggggtgggggagaaaccgcagtacgaa
cgctatactgccgctttggggctgcatactaatgatgctggttgtccggaatttactctt
cgccttcccgacgccagcgaatatgagatttcctccaaactcattggtgagcatcatgta
tgcaatattctggcggctgctacggtagcctataacgctggtgttcctggagacgctatt
gcgcatgccctcaataacaccggggcgctgtctaaatggaggatggctcgcacagaccgc
gcagacggcgtgactgttatcaacgatgcgtataatgctaatcccgagtcaatgacagcc
gctttacgcactttggcccaactgggacgaggcgcgaagccacgacggacttgggcagtt
ttgggggccatgctcgaactgggcgaggcctctttggaggagcacgatcgactcggtcgt
ctggtggtacgcatgaatatatcaaagcttattgcggttgggaatgaggcgaaaccagcc
tacaacgccgcgcatcttgaaggttcatggggtaacgaagctacctgggtagagacaccg
caagaagcactaaatattttgcgtgcagagttacgttctggcgatattgtgctgtttaaa
tcttcaaatggcgctaaactaggttctttgggcgatgaggttgccttctgcaccgagacc
tttggcgaggctcaagaacaggctccagcttggctgagtgctggcgattttgttgaggtg
acggatttaacgggcgccgctctgagcacggtatcagctggtagttctgcagcgcaaacc
tcgacgaccgccctagaccgtagccatcttcacgaaggaacacattaa
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