KEGG   Cupriavidus necator H16: H16_A1549
Entry
H16_A1549         CDS       T00416                                 
Symbol
leuC2
Name
(GenBank) 3-Isopropylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
reh  Cupriavidus necator H16
Pathway
reh00290  Valine, leucine and isoleucine biosynthesis
reh00660  C5-Branched dibasic acid metabolism
reh01100  Metabolic pathways
reh01110  Biosynthesis of secondary metabolites
reh01210  2-Oxocarboxylic acid metabolism
reh01230  Biosynthesis of amino acids
Module
reh_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:reh00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    H16_A1549 (leuC2)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    H16_A1549 (leuC2)
Enzymes [BR:reh01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     H16_A1549 (leuC2)
    4.2.1.35  (R)-2-methylmalate dehydratase
     H16_A1549 (leuC2)
SSDB
Motif
Pfam: Aconitase
Other DBs
NCBI-ProteinID: CAJ92681
UniProt: Q0KBE0
LinkDB
Position
1:1682613..1684034
AA seq 473 aa
MSAMSQGRTLFDKIWQAHAIAELDGASLLHIDRVFLHERTGSIALSSLRAAGRRVRAPAL
AFCTMDHIVDTRPGRNDSTLMPGGEAFITSTRDSARREAIRLFDIGDPGQGIVHVVSPEQ
GIALPGTTVVCPDSHTCTQGGLGALAWGIGSSEAEHALATQTLRVTRPRTMRVSFDGALP
AGVGAKDLMLWLIARYSAAGAGGHMLEFGGSAVRSLPVEARLTLCNLAVEFSAFSGIVAP
DDTVFEYLAGRPYAPAGAQWEPALWHWRSLYSDADAVFDRELSVDCRQLAPMVTWGTSPQ
HGVAVDGAVPNPAMAIDADTRQAMERALSYMDLRPGQRMADIAIDAAFIGSCTNSRLSDL
RSAAGVLAGRKVAPGVTAICVPVSSAVKRAAEAEGLDRVFREAGFEWRESGCSMCFYAGG
ESFGHRQRVISSTNRNFESRQGPQTRTHLAGPATVAASAVLGRIADPRRPPGA
NT seq 1422 nt   +upstreamnt  +downstreamnt
atgagcgccatgtcccagggccggaccctgttcgacaagatttggcaggcgcatgccatt
gccgaactggacggcgccagcctgctgcatatagaccgcgtcttcctgcacgagcgcacc
ggcagcatcgcgctgagctcgctgcgcgcggccgggcggcgcgtgcgcgcgccggcgctg
gcgttctgcaccatggaccatatcgtcgatacgcggcccgggcgcaacgacagcacgctg
atgccgggcggcgaggcctttatcaccagcacgcgcgacagcgccaggcgcgaggccatc
cggctgttcgatatcggcgatcccggccagggcatcgtccatgtggtgtcgccggaacag
ggcattgccttgcccggcaccaccgtggtctgtcccgacagccatacctgcacgcagggc
ggcctgggcgcgctggcctggggcatcggctcgtccgaggcggaacatgcgctggcgacg
cagacgctgcgcgtgacgcggccgcgcaccatgcgggtgtcgttcgacggcgcgctgcca
gcgggcgtcggcgccaaggacctgatgctgtggctgatcgcacgctactcggcggcgggc
gccggcggccatatgctcgaattcggcggcagcgcggtgcgcagcctgccggtcgaggcg
cgcctgacgctgtgcaacctggcggtggagttctcggcgttctcgggcattgtcgcgccc
gacgacacggtcttcgaatacctcgccggccggccgtatgcgcccgccggtgcgcagtgg
gaaccagcgctgtggcactggcgcagcctgtacagcgacgccgacgccgtgttcgaccgc
gagctgtcggtggattgcaggcagctggcgccgatggtgacctggggcaccagcccgcag
cacggcgtggccgtcgacggcgccgtgcccaaccccgccatggcgatcgatgccgatacg
cgccaggccatggagcgcgcactgtcctacatggacctgcgtcccgggcagcggatggcg
gacatcgccatcgatgccgcatttatcggctcctgcaccaacagccggctgtcggacctg
cgcagcgcggccggtgtgctggccgggcgtaaggtggcgcccggcgtgacggccatctgc
gtgccggtttccagcgccgtcaagcgcgccgccgaggccgaagggctggatcgcgtgttc
cgtgaagcgggattcgagtggcgtgaatcgggttgctcgatgtgcttctacgccggcggc
gaaagcttcggccaccggcagcgcgtgatcagcagcaccaaccgcaattttgaaagccgc
cagggcccgcagacccgcacccaccttgccggcccggccacggtggcggcatcggccgtg
ctggggcgcatcgccgacccgcgccggccgccaggagcctga

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