Cupriavidus necator H16: H16_A1549
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Entry
H16_A1549 CDS
T00416
Symbol
leuC2
Name
(GenBank) 3-Isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
reh
Cupriavidus necator H16
Pathway
reh00290
Valine, leucine and isoleucine biosynthesis
reh00660
C5-Branched dibasic acid metabolism
reh01100
Metabolic pathways
reh01110
Biosynthesis of secondary metabolites
reh01210
2-Oxocarboxylic acid metabolism
reh01230
Biosynthesis of amino acids
Module
reh_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
reh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
H16_A1549 (leuC2)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
H16_A1549 (leuC2)
Enzymes [BR:
reh01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
H16_A1549 (leuC2)
4.2.1.35 (R)-2-methylmalate dehydratase
H16_A1549 (leuC2)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
CAJ92681
UniProt:
Q0KBE0
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Position
1:1682613..1684034
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AA seq
473 aa
AA seq
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MSAMSQGRTLFDKIWQAHAIAELDGASLLHIDRVFLHERTGSIALSSLRAAGRRVRAPAL
AFCTMDHIVDTRPGRNDSTLMPGGEAFITSTRDSARREAIRLFDIGDPGQGIVHVVSPEQ
GIALPGTTVVCPDSHTCTQGGLGALAWGIGSSEAEHALATQTLRVTRPRTMRVSFDGALP
AGVGAKDLMLWLIARYSAAGAGGHMLEFGGSAVRSLPVEARLTLCNLAVEFSAFSGIVAP
DDTVFEYLAGRPYAPAGAQWEPALWHWRSLYSDADAVFDRELSVDCRQLAPMVTWGTSPQ
HGVAVDGAVPNPAMAIDADTRQAMERALSYMDLRPGQRMADIAIDAAFIGSCTNSRLSDL
RSAAGVLAGRKVAPGVTAICVPVSSAVKRAAEAEGLDRVFREAGFEWRESGCSMCFYAGG
ESFGHRQRVISSTNRNFESRQGPQTRTHLAGPATVAASAVLGRIADPRRPPGA
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccatgtcccagggccggaccctgttcgacaagatttggcaggcgcatgccatt
gccgaactggacggcgccagcctgctgcatatagaccgcgtcttcctgcacgagcgcacc
ggcagcatcgcgctgagctcgctgcgcgcggccgggcggcgcgtgcgcgcgccggcgctg
gcgttctgcaccatggaccatatcgtcgatacgcggcccgggcgcaacgacagcacgctg
atgccgggcggcgaggcctttatcaccagcacgcgcgacagcgccaggcgcgaggccatc
cggctgttcgatatcggcgatcccggccagggcatcgtccatgtggtgtcgccggaacag
ggcattgccttgcccggcaccaccgtggtctgtcccgacagccatacctgcacgcagggc
ggcctgggcgcgctggcctggggcatcggctcgtccgaggcggaacatgcgctggcgacg
cagacgctgcgcgtgacgcggccgcgcaccatgcgggtgtcgttcgacggcgcgctgcca
gcgggcgtcggcgccaaggacctgatgctgtggctgatcgcacgctactcggcggcgggc
gccggcggccatatgctcgaattcggcggcagcgcggtgcgcagcctgccggtcgaggcg
cgcctgacgctgtgcaacctggcggtggagttctcggcgttctcgggcattgtcgcgccc
gacgacacggtcttcgaatacctcgccggccggccgtatgcgcccgccggtgcgcagtgg
gaaccagcgctgtggcactggcgcagcctgtacagcgacgccgacgccgtgttcgaccgc
gagctgtcggtggattgcaggcagctggcgccgatggtgacctggggcaccagcccgcag
cacggcgtggccgtcgacggcgccgtgcccaaccccgccatggcgatcgatgccgatacg
cgccaggccatggagcgcgcactgtcctacatggacctgcgtcccgggcagcggatggcg
gacatcgccatcgatgccgcatttatcggctcctgcaccaacagccggctgtcggacctg
cgcagcgcggccggtgtgctggccgggcgtaaggtggcgcccggcgtgacggccatctgc
gtgccggtttccagcgccgtcaagcgcgccgccgaggccgaagggctggatcgcgtgttc
cgtgaagcgggattcgagtggcgtgaatcgggttgctcgatgtgcttctacgccggcggc
gaaagcttcggccaccggcagcgcgtgatcagcagcaccaaccgcaattttgaaagccgc
cagggcccgcagacccgcacccaccttgccggcccggccacggtggcggcatcggccgtg
ctggggcgcatcgccgacccgcgccggccgccaggagcctga
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