Cupriavidus necator H16: H16_A2266
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Entry
H16_A2266 CDS
T00416
Symbol
thrA
Name
(GenBank) homoserine dehydrogenase
KO
K00003
homoserine dehydrogenase [EC:
1.1.1.3
]
Organism
reh
Cupriavidus necator H16
Pathway
reh00260
Glycine, serine and threonine metabolism
reh00270
Cysteine and methionine metabolism
reh00300
Lysine biosynthesis
reh01100
Metabolic pathways
reh01110
Biosynthesis of secondary metabolites
reh01120
Microbial metabolism in diverse environments
reh01230
Biosynthesis of amino acids
Module
reh_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
reh00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
H16_A2266 (thrA)
00270 Cysteine and methionine metabolism
H16_A2266 (thrA)
00300 Lysine biosynthesis
H16_A2266 (thrA)
Enzymes [BR:
reh01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
H16_A2266 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
NAD_binding_3
ACT
GFO_IDH_MocA
ACT_4
ACT_AHAS_ss
Peptidase_S66
DXP_reductoisom
Sacchrp_dh_NADP
ACT_7
Motif
Other DBs
NCBI-ProteinID:
CAJ93363
UniProt:
Q0K9F8
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Position
1:complement(2460107..2461417)
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AA seq
436 aa
AA seq
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MNPIKVGLLGIGTVGSGTFNVLKRNQEEIRRRAGRGIEIAVVADLNTERARELTNGEVEI
VSDANEVVSRPDIDIVIELIGGYGIARELVLKAIENGKHVVTANKALLAVHGNEIFEAAR
KKGVIVAFEAAVAGGIPIIKALREGLTANRIQWIAGIINGTTNFILSEMRDKGLDFDVVL
KEAQQLGYAEADPTFDIEGVDAAHKVTLMSAIAFGMPVQFDKAHVEGITKLSAIDIKYAE
ELGYRIKLLGITRRRDDGVELRVHPTLVPASRLIANVEGAMNAVLVQGDAVGATLYYGKG
AGAEPTASAVIADLVDVTRLHTADPNHRVPHLAFQPDELSSVPVLPIEEINSSYYLRMRV
ADETGVLAEITRILAEGGISIDAMLQKESREGEPQTDIIILTHITREKHVNAAIAKIEAL
PTVLSAVTRLRMEELN
NT seq
1311 nt
NT seq
+upstream
nt +downstream
nt
atgaaccccatcaaagttggcctgctcggcatcggtaccgtcggtagcggcacgttcaac
gtgctcaagcgcaatcaggaagaaattcgtcgccgcgccggccgcggcatcgagattgcc
gtggtggccgatctcaacaccgaacgcgcgcgcgaactgaccaacggggaagtggagatc
gtcagcgacgccaacgaggtggtcagccgcccggacatcgatatcgtcatcgaactgatc
ggcggctacggcatcgcgcgtgagctggtgctcaaggcgatcgagaacggcaagcacgtg
gtcaccgccaacaaggcgctgctggccgtgcacggcaacgagatcttcgaagccgcgcgc
aagaagggcgtgatcgtcgccttcgaagccgcggtggccggcggcatccccatcatcaag
gcgctgcgcgagggcctgaccgccaaccgcatccagtggatcgccggcatcatcaacggc
accaccaacttcatcctgtccgagatgcgcgacaagggcctcgatttcgacgtggtgctg
aaggaagcccagcagctcggctacgccgaagccgacccgaccttcgacatcgaaggcgtc
gatgccgcgcacaaggtcacgctgatgagcgcgatcgccttcggcatgccggtgcagttc
gacaaggcccacgtggaaggcatcaccaagctgtcagccatcgacatcaagtacgccgag
gaactgggctaccgcatcaagctgctgggcatcacccgccgccgcgacgacggtgtcgag
ctgcgcgtgcatccgacgctggtgccggcctcgcgcctgatcgccaacgtcgaaggcgcg
atgaacgcggtgctggtgcagggcgacgccgtgggcgcgacgctctactacggcaagggt
gccggcgccgagccgaccgcctcggccgtgatcgctgacctggtcgacgtgacccgcctg
cacaccgccgatcccaaccaccgcgtgccgcacctggcgttccagccggacgagctgtcg
agcgtgccggtgctgccgatcgaagagatcaacagctcgtactacctgcgcatgcgcgtg
gccgacgagaccggcgtgctggccgagatcacccgcatcctggccgagggcggcatctcg
atcgacgccatgctgcagaaggaatcgcgcgagggcgagccgcagaccgacatcatcatc
ctcacgcacatcacgcgcgagaagcacgtcaacgcggcgatcgccaagatcgaggcgctg
cccaccgtgctgtccgccgtgacgcgcctgcgcatggaagaactgaactaa
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