Rhodococcus erythropolis PR4: RER_16430
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Entry
RER_16430 CDS
T00881
Symbol
cysGA_hemD
Name
(GenBank) uroporphyrinogen-III methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
rer
Rhodococcus erythropolis PR4
Pathway
rer00860
Porphyrin metabolism
rer01100
Metabolic pathways
rer01110
Biosynthesis of secondary metabolites
rer01120
Microbial metabolism in diverse environments
rer01240
Biosynthesis of cofactors
Module
rer_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
rer_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
rer00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
RER_16430 (cysGA_hemD)
Enzymes [BR:
rer01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
RER_16430 (cysGA_hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
RER_16430 (cysGA_hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BAH32351
UniProt:
C0ZUV6
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Position
1783809..1785371
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AA seq
520 aa
AA seq
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MTRVRKNTPGRILFVGSGPGDPALLTVRARDVLTGAAMAFTDPDVDKGVVALVGIDMGRD
EETGELIADVRPALGEPAEVAKTLVHEAKNGHDVVRLVSGDPLTTDSVIAEVTAVARTQV
QFEVLPGLPSGSAVPSYAGMALGSGHTEADVRGEVDWAALAAAPGPLVLHATSGHLAETA
SALVENGLAPQTPAAITVRGTTRQQRTVEATLATLNEAGSELVGSLIVTVGKVVAQRNKM
SWWESRALYGWTVLVPRTKDQAGEMSDRLVTHGAIPIEVPTIAVEPPRSPAQMERSVKGL
VDGRYQWVVFTSTNAVRAVWEKFEEFGLDARAFSGVKIACIGEATAAKVRSFGINPELIP
TGEQSSEGLLAEFAPYDDVFDPVNRVLLPRADIATETLAEGLRERGWEIDDVTAYRTVRA
APPPAETREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPKTAETAIEFGLR
VDVQPETSQVGPLVEALAEHAARLRAEGALPPPRKKSRRR
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgacccgagtccgaaagaacactcccggacggatcctgttcgtgggatcgggaccgggc
gaccccgccctgctcaccgttcgcgcacgtgacgtcctcaccggcgccgcaatggcattc
accgatccggatgtcgacaagggcgtcgtcgcgctcgtcggcatcgacatgggccgcgac
gaggagaccggcgagctgatcgcggacgtgcgtccggcactcggtgagcctgccgaggtt
gcaaagacattggtgcacgaggccaagaacggccacgacgtcgtgcgtctggtctccggt
gatccgctgaccacggattccgtgatcgcagaggtcacggcagtcgcccgcacgcaggtt
cagttcgaggttctcccgggtctgccttcgggttcggctgtgccgagctacgccggtatg
gcgctcggctcgggtcacaccgaggccgacgttcgcggtgaagtcgactgggctgctctg
gccgctgcaccgggaccgcttgttctgcacgcgacgtcgggacatctcgccgagaccgcc
agcgcgctggtcgagaacggcttggctccgcagacgcctgctgccatcaccgtccgcggc
accactcgtcagcagcgaaccgtcgaggcaactctcgcgacgctcaacgaagccggatcc
gaactggtgggctcgctcatcgtcaccgtcggcaaggttgtcgcgcagcgcaacaagatg
tcgtggtgggaatcgcgcgctctgtacggctggactgtcctcgtgccgcgcaccaaggat
caggccggcgagatgagcgaccgtctggtcactcacggagcgatcccgatcgaggttccg
accatcgccgtcgagccgcctcgcagcccggctcagatggagcgttcggtcaagggcctc
gtcgacggtcgttaccagtgggtggtcttcacttccaccaatgcggttcgcgcagtgtgg
gagaagttcgaggagttcggtctcgacgctcgcgccttctccggcgtgaagatcgcctgt
atcggcgaagcaaccgcagccaaggtccgctcgttcggcatcaaccccgagctgatcccg
accggtgagcagtccagcgaaggcctgctggccgaattcgccccgtacgacgacgttttt
gatccggtcaaccgggttctgttgccgcgcgcggacattgcaaccgaaaccctcgccgag
ggcctgcgcgaacgcggttgggagatcgacgacgtcaccgcctaccgcaccgtccgggcg
gcgccgccgccggccgagacccgcgagatgatcaagaccggtggattcgacgccgtctgc
ttcacctcgtcctcgaccgtgcgcaacctcgtcggcatcgccggcaagccgcacgcccgc
acgttggtcgcgtgcatcggcccgaagacggccgaaaccgctatcgagttcggtctgcgc
gtcgacgtgcagcccgagacctcgcaggtgggaccgctggtggaggctctcgccgagcac
gcagctcggctgcgcgctgaaggtgctttgccgccgccgcgtaagaagtcccgcaggcgc
tag
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