KEGG   Rhodococcoides fascians D188: A3L23_01288
Entry
A3L23_01288       CDS       T04328                                 
Symbol
leuA_1
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
rfa  Rhodococcoides fascians D188
Pathway
rfa00290  Valine, leucine and isoleucine biosynthesis
rfa00620  Pyruvate metabolism
rfa01100  Metabolic pathways
rfa01110  Biosynthesis of secondary metabolites
rfa01210  2-Oxocarboxylic acid metabolism
rfa01230  Biosynthesis of amino acids
Module
rfa_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:rfa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    A3L23_01288 (leuA_1)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    A3L23_01288 (leuA_1)
Enzymes [BR:rfa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     A3L23_01288 (leuA_1)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: AMY52639
LinkDB
Position
complement(1373274..1375088)
AA seq 604 aa
MRTDFFTLSTPAGPVPVGAPTWNRQRHSQMPSHRYRDVYAKVDIPLTRRRWPERRLTEAP
LWVPVDLRDGNQALPEPMDPARKKQFFELMVAMGYKEIEVGYPSASQTDFDFVRLLAHTD
LAPDDVTVVVFTPARRDLIERTVESIRGITNDVVIHMYTATAPTWREVVLGREANELRSL
ILSGAADVLELAGDLPNVRFEFSPEVFNLTEPDYVLDVCDAVTTLWDATQQRPVILNLPA
TVEVATPNVYADQIEYMNDNLARRDSVILSVHPHNDRGTGIACAELAVLAGAQRVEGCVF
GNGERTGNVDIATLALNLHAQGVDPMIDFSDIDQIRRTVEYCNQLEIHPRHPYVGDLVHT
AFSGTHQDAIKKGFVEHRARALSEGRSERDIEWRVPYLPIDPDDIGRSYDAVIRVNSQSG
KGGIAYLLETHYGIELPRRLQIDLARHVQARTDSIGTELTAEQLWDIFEQVYIGVAEPDV
ALVGFDSHDNDGSADTCITLKIDGATFETSHTGVGPVEALVDALSAHGRHVDILGLTQTS
VRAGNDSDAVSMLEYRTATGSRWAAGIDRSVLSATLDAVLRAAGSATQRDYVLGSDRRPP
HVGG
NT seq 1815 nt   +upstreamnt  +downstreamnt
atgcgcacagatttcttcactctgtccactcccgccggacccgttcccgtcggcgcgccc
acctggaatcggcagcggcactcccagatgccgtcgcatcgttaccgtgacgtctacgcc
aaggtcgacattccgctgacccggcgtcgctggccggagcgacggttgaccgaggcgccg
ctgtgggtgccggtcgatctgcgcgacggcaaccaagcgttgcccgagccgatggatcct
gcccgcaaaaaacagttcttcgagttgatggttgcgatgggctacaaggaaatcgaagtc
gggtatccctcggcatcgcagaccgatttcgatttcgtgcggctgctggcacacaccgat
ctggcacccgacgacgtcaccgtggtcgtcttcaccccggctcgacgcgacctgatcgag
cgaaccgtggagtcgatccgcggaatcaccaacgacgtcgtgatccacatgtacaccgcc
acggctcctacgtggcgcgaggtcgtgctcggccgggaggccaacgagcttcgctcactg
atactttcgggcgcagccgacgttctcgaacttgccggcgacctgcccaacgtgcgattc
gagttctcacccgaggtcttcaatctcaccgaacccgactacgtcctcgatgtctgcgat
gcggtgacgactctgtgggacgcgacgcagcagcggccggtcatcctgaatttgcctgcc
acagtggaggtcgcgacgccgaatgtctatgcggaccagatcgagtacatgaacgacaac
cttgcgcgacgagacagcgtaatcctgtcggtgcatccacacaacgaccgcgggaccggc
attgcctgcgccgagctggccgtcctggccggagcgcagcgggtggagggctgcgtgttc
ggcaacggcgagcgcaccggaaacgtcgacatcgctactctcgcactgaatttgcacgcg
cagggtgtcgatcccatgatcgacttctccgacatcgatcagattcgacgcaccgtcgaa
tactgcaaccagctcgagattcacccgcggcatccgtatgtcggcgacctcgtacacacc
gccttcagcggtacgcaccaggacgccatcaagaagggtttcgtcgagcatcgcgctcgg
gcgctgagcgaaggccgttccgagcgcgatatcgaatggcgggtgccgtacttgccgatc
gaccccgacgacatcggtcgatcgtacgacgcggtcattcgcgtcaattcgcaatcgggc
aagggaggaatcgcgtacctcctcgaaacccactacggcatcgaacttccgcgtcgcctg
cagatcgacctcgcccggcacgtgcaggcccgcacggattcgatcggtaccgaactgacg
gccgagcaactctgggacatcttcgagcaggtgtacatcggtgtcgccgaacccgacgtg
gcgctggtcggcttcgactctcacgacaacgacgggtcggccgacacctgcatcacattg
aagatcgacggcgcgaccttcgagacatcacacacgggagtcggcccggtcgaggcactt
gtcgacgcgttgtccgcccatggccggcacgtggacatcctcggtctgacgcagaccagt
gtgcgagccggcaacgacagtgatgcggtctcgatgctcgaataccgcactgccaccggg
tctcgatgggcggcagggatcgatcgctccgtcctgtccgccaccctcgacgcagtcctt
cgtgccgccggctcggcgacccagcgggactacgtgctcggtagcgatcggcgtccgccg
catgtcggtggctga

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