Rhodococcoides fascians D188: A3L23_03947
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Entry
A3L23_03947 CDS
T04328
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rfa
Rhodococcoides fascians D188
Pathway
rfa00300
Lysine biosynthesis
rfa00550
Peptidoglycan biosynthesis
rfa01100
Metabolic pathways
rfa01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rfa00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A3L23_03947 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A3L23_03947 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A3L23_03947 (murF)
Enzymes [BR:
rfa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A3L23_03947 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AMY55260
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Position
4126857..4128380
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AA seq
507 aa
AA seq
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MIPLSIARIAEIVGGELHDVADPTVLVAGPVEFDSRKVTPGSVFLALPGAKVDGHEHAAD
AVAAGASVVLAARPVGVPAVVVRPAPHASRAMALEHDPEGAGAAVLTALGALARESVLEL
TAHHDLTVVGVTGSSGKTSTKDLISAVLRPLGSVVAPPGSFNNELGHPWTALRADSDTDF
LALELSARGIGHIAELARLAPPRIGVVLNVGTAHLGEFGSRAAIALAKGELVEALPAAAD
GGVAILNIDDRLVAEMATRTKAAVVTVGLNADADVRAVDVVVDTDARASFTLVCAAGSAH
ITLAVHGEHQVGNALAAAAVALECGAGVAQVAEALSTAVPTSIRRMDVRTRADGVTVIND
SYNANPDSMRAALKALVSMSRRDDGPKRRSWAVLGEMGELGGESVVEHDAIGRLAVRLDV
DRLIIVDSGRPTRALHQGAVMEGSWGEESMLVPDRETAIAVLEDEVRAGDIVLVKASQSG
AMWTVADALLAEPSADALLAEPSEGEQ
NT seq
1524 nt
NT seq
+upstream
nt +downstream
nt
gtgataccgctctcgatcgctcgcatcgccgagatcgtcggcggcgaactgcacgacgtg
gcggacccgacggtgctggtcgccgggccggtggagttcgactcacgcaaggtcacaccc
ggcagtgtctttctcgccctgcccggtgccaaggtggacggccacgagcacgcggccgac
gccgtggccgcaggcgcttctgtcgttctcgcggcgcgtccggtgggcgtcccggctgtc
gtcgttcggccggcgccgcacgcgagccgtgcgatggcactcgaacacgacccggagggg
gccggcgctgcggtgctgaccgcgctcggtgcattggcccgggaatcggtgctcgaactg
accgcgcaccacgacctgaccgtggtgggcgtgacggggtcgtcgggcaagacgtcgacg
aaggatctcatctcggctgtgctgcgtccgctcggatccgtggtggccccacccggatcg
ttcaacaacgaactcgggcatccatggactgctctgcgggccgactccgataccgacttc
ctcgccctcgagctgtccgcccggggaatcggccacatcgccgaactcgccaggctcgcg
ccgccccggatcggggtggttctcaatgtcggaaccgcgcacctgggcgagttcggttca
cgtgccgccatcgcgctggccaagggcgaactggtcgaggcattgcccgctgctgcggac
ggcggcgtggcgatcctcaacatcgacgatcgtctggtcgccgagatggcgacacgcacg
aaggcggccgtcgtcaccgtcggactcaacgcggacgccgacgtccgggctgtcgacgtc
gtggtcgacaccgatgcgcgggcgtcgttcacgctcgtgtgtgcggcaggctcggcgcac
atcaccctggcggtgcacggtgaacatcaggtgggcaacgccctggctgccgcggccgtc
gcgctcgagtgcggggccggcgtggcccaggttgccgaagcgctctcgaccgcggtaccc
acctcgatccgccggatggatgtacgcacccgcgcggacggcgtcaccgtcatcaacgac
tcgtacaacgcgaatcccgattcgatgcgggccgccctcaaggcgctggtgtcgatgtcg
cggcgtgatgacgggccgaagcggcgcagttgggcggtgctgggggagatgggcgagctc
ggcggcgaatcggtggtggagcacgatgcgatcggtcggctcgccgtccgcctggacgtc
gatcggttgatcatcgtcgattcgggtcggcccacgcgtgcgctgcatcagggcgccgtc
atggaagggtcctggggcgaggaatcgatgctcgtacccgaccgcgagaccgccatcgcc
gtgctcgaggacgaggttcgcgccggcgacatcgttctggtcaaggcctcgcagtcgggc
gcgatgtggaccgttgccgacgccctgttggccgaaccgtcggccgacgccctgttggcc
gaaccgtcggagggcgagcagtga
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