KEGG   Rhinolophus ferrumequinum (greater horseshoe bat): 117012542
Entry
117012542         CDS       T07722                                 
Symbol
HGF
Name
(RefSeq) hepatocyte growth factor isoform X1
  KO
K05460  hepatocyte growth factor
Organism
rfq  Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq01521  EGFR tyrosine kinase inhibitor resistance
rfq04010  MAPK signaling pathway
rfq04014  Ras signaling pathway
rfq04015  Rap1 signaling pathway
rfq04020  Calcium signaling pathway
rfq04151  PI3K-Akt signaling pathway
rfq04510  Focal adhesion
rfq04518  Integrin signaling
rfq05144  Malaria
rfq05200  Pathways in cancer
rfq05205  Proteoglycans in cancer
rfq05208  Chemical carcinogenesis - reactive oxygen species
rfq05211  Renal cell carcinoma
rfq05218  Melanoma
rfq05223  Non-small cell lung cancer
rfq05225  Hepatocellular carcinoma
rfq05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:rfq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    117012542 (HGF)
   04014 Ras signaling pathway
    117012542 (HGF)
   04015 Rap1 signaling pathway
    117012542 (HGF)
   04020 Calcium signaling pathway
    117012542 (HGF)
   04151 PI3K-Akt signaling pathway
    117012542 (HGF)
  09133 Signaling molecules and interaction
   04518 Integrin signaling
    117012542 (HGF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    117012542 (HGF)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117012542 (HGF)
   05205 Proteoglycans in cancer
    117012542 (HGF)
   05208 Chemical carcinogenesis - reactive oxygen species
    117012542 (HGF)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    117012542 (HGF)
   05226 Gastric cancer
    117012542 (HGF)
   05218 Melanoma
    117012542 (HGF)
   05211 Renal cell carcinoma
    117012542 (HGF)
   05223 Non-small cell lung cancer
    117012542 (HGF)
  09174 Infectious disease: parasitic
   05144 Malaria
    117012542 (HGF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    117012542 (HGF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:rfq04052]
    117012542 (HGF)
   00536 Glycosaminoglycan binding proteins [BR:rfq00536]
    117012542 (HGF)
Cytokines and neuropeptides [BR:rfq04052]
 Cytokines
  Growth factors (RTK binding)
   117012542 (HGF)
Glycosaminoglycan binding proteins [BR:rfq00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   117012542 (HGF)
SSDB
Motif
Pfam: Kringle Trypsin PAN_1 Nudel DUF316 Sterile
Other DBs
NCBI-GeneID: 117012542
NCBI-ProteinID: XP_032944791
Ensembl: ENSRFEG00010020505
UniProt: A0A671FZJ2
LinkDB
Position
20:42536402..42607353
AA seq 730 aa
MWVTKLLPVLLLQHVLLHLLLLPIAIPYAEGQKKRRNTLHEFKKSAKTTLFKEDPLLKIK
TKKMNTADQCANRCVRNKGLPFTCKAFVFDKTRKRCLWFPVNSMSSGVKKEFGHEFDLYE
NKDYIRNCIIGKGGSYKGTVSVTKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRNP
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTESGKICQRWDHQTP
HRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDTDVPF
ETTECIKAQGEGYRGTINTIWNGIPCQRWDSQYPHQHDITPENFKCKDLRENYCRNPDGA
ESPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNME
DLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNL
DHPVISCAKTKQLRVVNGIPTRTNVGWMVSLKYRNKHICGGSLIKESWILTARQCFPSRN
KDLKDYEAWLGIHDVHGRGDEKRKQVLNVSQLVYGPEGSDLVLLKLARPAVLDDFVSTID
LPNYGCTIPEKTTCSIYGWGYTGLINSDNLLRVAHLSIMGNEKCSQYHQGKVTLNESEIC
AGSENIVTGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHK
IILTYKVPQL
NT seq 2193 nt   +upstreamnt  +downstreamnt
atgtgggtgaccaaacttctgccagtcctgctgctgcagcatgtcctcctacatctcctc
ctgcttcccatcgccatcccctatgcagaaggacagaagaaaagaagaaacacacttcat
gaattcaaaaagtcagcaaagactactctatttaaagaagacccattactgaagataaaa
acaaaaaaaatgaacacagcagaccaatgtgccaatagatgtgttaggaataaaggactt
ccattcacttgcaaggcctttgtttttgataaaacaagaaaacgatgcctctggttccct
gtcaatagcatgtcaagtggagtgaaaaaagaatttggccatgagttcgacctctatgaa
aacaaagactacattagaaactgcatcattggtaaaggaggtagctacaagggaacggta
tctgtcactaagagtggcatcaaatgccagccctggaattccatgataccacacgaacac
agctttttgccttcgagctatcggggtaaagacctacaggaaaactactgtcgaaatcct
cgaggggaagaagggggaccttggtgtttcacaagcaatccagaggtacgctacgaagtc
tgtgacattcctcagtgttcagaagttgaatgcatgacctgcaatggggaaagttaccga
ggtcccatggatcatacagaatcaggcaagatttgtcagcgctgggatcatcagacgcca
catcggcacaaattcttgccagaaagatatcccgacaagggctttgatgataattattgc
cgcaatcctgacggcaagccgaggccatggtgctacactcttgaccctgacaccccttgg
gagtactgtgcaattaaaatgtgcgctcacagtactatgaatgacacggatgtccctttc
gaaacaactgaatgcattaaagctcaaggagaaggttaccggggcaccatcaataccatt
tggaatggaattccatgtcagcgatgggattcccagtaccctcaccagcatgacataact
cctgaaaatttcaagtgcaaggacctaagagaaaattattgccgaaatccagatggggct
gagtcaccctggtgttttaccactgatccaaacatccgagtcggctactgctcccaaatt
ccaaaatgtgacgtgtcaagtggacaagattgttatcgtgggaatggcaaaaattatatg
ggcaatttatccaaaacacgatctggactaacatgttcaatgtgggacaagaacatggaa
gacttacaccggcacatcttctgggaaccagatgctagtaagctaaataagaattactgc
cggaatcctgatgatgacgcccatggtccctggtgttacaccgggaatcctctcattcct
tgggattactgccctatttctcgttgtgaaggtgatactacacctacaatagtcaattta
gaccatcctgtaatatcttgcgccaaaacaaaacaactgcgagttgtaaatggaattcca
acacgaacaaatgtaggatggatggttagtttgaaatacagaaataaacatatctgcgga
ggatcattgataaaggaaagttggattctaacggcaagacagtgtttcccttcacgaaac
aaagacttgaaagattatgaagcttggcttggaattcatgatgtccatggaagaggagac
gagaaacgcaaacaggttctgaatgtttcccaactggtatatgggcctgaaggatcagat
ctggtgttgctgaagcttgctagacctgctgtcctggatgattttgttagtacaattgat
ttgcctaattatggatgcacaattcctgaaaaaaccacttgcagtatttatggatggggc
tacactggattgatcaactctgataatctattacgagtagcccatctctctattatgggg
aatgagaaatgcagccagtatcatcaagggaaggtgactttgaatgaatctgaaatatgt
gctggatctgaaaatattgtaacaggaccatgcgagggtgattatggtggcccacttgtt
tgtgaacaacataaaatgagaatggttcttggtgtcattgttcctggtcgtggatgtgcc
attccaaatcgtcctggcatttttgtccgagtagcatattatgcaaaatggatacacaaa
attatattaacttataaggtaccacagttatag

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