Rhinolophus ferrumequinum (greater horseshoe bat): 117013115
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Entry
117013115 CDS
T07722
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq04140
Autophagy - animal
rfq04141
Protein processing in endoplasmic reticulum
rfq04210
Apoptosis
rfq04932
Non-alcoholic fatty liver disease
rfq05010
Alzheimer disease
rfq05012
Parkinson disease
rfq05014
Amyotrophic lateral sclerosis
rfq05016
Huntington disease
rfq05017
Spinocerebellar ataxia
rfq05022
Pathways of neurodegeneration - multiple diseases
rfq05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
117013115 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
117013115 (ERN1)
09143 Cell growth and death
04210 Apoptosis
117013115 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
117013115 (ERN1)
05012 Parkinson disease
117013115 (ERN1)
05014 Amyotrophic lateral sclerosis
117013115 (ERN1)
05016 Huntington disease
117013115 (ERN1)
05017 Spinocerebellar ataxia
117013115 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
117013115 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
117013115 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
117013115 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rfq01001
]
117013115 (ERN1)
Enzymes [BR:
rfq01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
117013115 (ERN1)
Protein kinases [BR:
rfq01001
]
Serine/threonine kinases: Other
IRE family
117013115 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
117013115
NCBI-ProteinID:
XP_032945820
Ensembl:
ENSRFEG00010015422
UniProt:
A0A671FBH3
LinkDB
All DBs
Position
21:complement(42539628..42619256)
Genome browser
AA seq
974 aa
AA seq
DB search
MPARLLLLLLALLLPGPGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGK
KQDIWYVVDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF
DYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKV
MHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVAVVPRGSTLPLLEGPQTEGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKSFEEVIHLVDQTPVNAPTTISQD
VEEKFTHAPAKPEAPVDSMLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQFQHQQFQK
ELEKIQLLQQQQLPFHAPGDVAQDTELLDSSGLYSESSGTSSPSTSPRASNHSFHSSSSA
SKAGTSPSLEQDDDDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILP
ECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQNDFAHLGL
EPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRH
SFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQA
NILLGAYSLDCLHPEKHEDVIARELIEQMIAMDPQKRPSAKHVLKHPFFWSLEKQLHFFQ
DVSDRIEKESLDGPIVKQLERGGRPVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRA
MRNKKHHYRELPVEVRETLGSLPEDFVRYFTSRFPHLLSHTYRAMELCSHERLFQPYYFH
PPPDPQPPVTPEAL
NT seq
2925 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctactgctgctgctgctggcgctgctgctgcccggccccgggattttt
ggaagtcccagcacagtgacacttcctgaaaccttgttgtttgtgtcaaccctggatgga
agtttgcatgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaagatcct
gtcctgcaagttccaacgcatgttgaagagcctgccttcctcccagatcctaatgatggc
agcctgtatacacttgggggcaagaataatgaaggcttgacgaaacttccctttaccatc
ccagagttggtacaggcatccccatgccgaagttcagatggaattctctacatgggtaaa
aagcaggacatttggtacgtcgttgaccttctgaccggggagaagcagcagactttgtca
tcagcctttgcagatagtctctgcccatcaacctctcttctgtatcttgggcgaacagag
tacaccatcaccatgtacgacaccaaaacccgagagctccggtggaacgccacctacttc
gactatgcggcctcgctgcctgaggatgacgtggactacaagatgtcccattttgtgtcc
aatggcgatgggctggtggtgactgtggacagtgaatctggcgacgtcctgtggatccaa
aactatgcctccccagtggtggccttttatgtctggcagcgggagggcctaaggaaggtg
atgcatatcaacgtcgctgtggagaccctgcgctatctgaccttcatgtctggggaggtg
gggcgcatcaccaagtggaagtaccccttccccaaggagacggaggccaagagcaagctg
acgcccaccctgtatgttggtaaatactctaccagcctctacgcctccccctcaatggtc
cacgagggggtcgccgttgtgccacgaggcagcactcttcctttgctggaaggcccccag
accgaaggtgtcaccattggggacaaaggggagtgtgtgatcacacccagcacggaccta
aagtttgaccccgggctcaaaggaaagaacaagctcaactacttaaggaactactggctt
ctgataggacaccatgaaaccccgctgtctgcatctaccaagatgctggagcgattcccc
aacaacctgcccaaacaccgggaaaatgtgattcctgctgactcagagaagagctttgag
gaagttatccacctggttgaccagactccagtgaacgcgcccaccaccatttctcaggac
gtggaggagaagttcactcacgcccccgccaagcccgaggcccccgtggactccatgctc
aaggacatcgccaccatcattctaagcaccttcctgctcatcggctgggtggccttcatc
atcacctaccccttgagcatgcatcaacagcagcagttccagcaccagcagttccagaag
gaactggagaaaatccagctcctgcaacagcagcagctgcccttccacgcacctggagac
gtggctcaggacaccgagctcctggactcgtccggcctgtactcagagagctcgggcacc
agcagccccagcacgtctcccagagcctccaaccactcgttccactccagcagttctgcc
tccaaggctggcaccagcccctccctggagcaggacgacgacgatgaggaaaccagcatg
gtgatggttgggaagatttcattctgtcccaaagacgtcctgggccacggagcggagggc
acaatcgtgtaccggggcatgttcgacaaccgtgacgtggcagtcaagaggatcctcccc
gagtgtttcagtttcgcagaccgcgaggtccagctgcttcgagagtcagatgagcaccca
aacgtgatccgttacttctgcacggagagggaccggcagttccagtacattgccattgag
ctgtgcgcggccactctgcaggagtacgtggagcagaatgactttgcccacctcggcctg
gagcccatcaccttgctgcagcagaccacctcgggtctggctcacctgcactccctgaac
attgttcacagagacctaaagccccacaacatcctcctctccatgcccaacgcacatggc
aggatcaaggccatgatctctgactttggcctctgcaagaagctggcagtgggcaggcac
agctttagccgccgttcaggagtgcccggcacggagggctggatcgctccagagatgctg
agtgaagactgcaaggagaaccctacctacacagtggacatcttctctgcgggctgcgtc
ttttactacgtgatatctgagggcagccacccttttggcaaatccctgcagcggcaagcc
aacatcctcctgggagcctacagccttgactgcttacaccccgagaagcacgaagatgtc
atcgccagagaactgatagagcagatgatcgcgatggaccctcagaagcgcccctcggcg
aaacacgtgctaaaacacccgttcttctggagcctagaaaagcagctccacttcttccag
gacgtgagtgaccgaatagaaaaggagtccctggacggcccgattgtgaagcagctggag
cgaggcgggaggcctgtggtgaagatggactggagggaaaacatcactgtccccctccag
acagatctgcgtaaattcagaacctataaaggcggctccgtccgagatctcctccgagcc
atgagaaataagaagcaccactaccgggagctccccgtggaggtgcgggagaccctgggc
tccctccccgaagacttcgtgcgctacttcacgtcgcgcttcccccacctcctgtcacac
acctaccgggccatggagctgtgcagccacgagaggctcttccagccctactacttccac
ccacccccggatcctcagcccccagtgactccagaggccctttga
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