Rhinolophus ferrumequinum (greater horseshoe bat): 117013825
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Entry
117013825 CDS
T07722
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
117013825 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
rfq03032
]
117013825 (TOP2A)
03036 Chromosome and associated proteins [BR:
rfq03036
]
117013825 (TOP2A)
Enzymes [BR:
rfq01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
117013825 (TOP2A)
DNA replication proteins [BR:
rfq03032
]
Eukaryotic type
DNA Topoisomerases
117013825 (TOP2A)
Chromosome and associated proteins [BR:
rfq03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
117013825 (TOP2A)
Centrosome formation proteins
Centriole proteins
117013825 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Motif
Other DBs
NCBI-GeneID:
117013825
NCBI-ProteinID:
XP_032947208
Ensembl:
ENSRFEG00010017407
LinkDB
All DBs
Position
21:complement(36795094..36819685)
Genome browser
AA seq
1583 aa
AA seq
DB search
MEVSPLQPVNENMQMNKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDIGMNFREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TATKEYKKMFKQTWMDNMGRASEMVLKPFSGEDYTCVTFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVTDQIVTKLIEVVKKKNKGGVAVKAHQVKNHV
WIFVNALIENPTFDSQTKENMTLQVKNFGSTCQLSEKFIKAAVGCGIVESILNWVKFKAQ
AQLNKKCSSVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKSLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEIAFYSLPEFEEWKC
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIRFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLCGLPEDYLYGQATTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPQDDHTLKFLYDDNQRVEPEW
YIPIIPMVLVNGAEGIGTGWSCKIPNYDIREIVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAANQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFIVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
EFFELRLKYYGLRKEWLLGMIGAESAKLNNQARFILEKIDGKIVIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENGESDNEKETEKSDSVTGPTFNYLLDMPLWYLTKEKKD
ELCKLKNEKEQELEILKRKSPSDLWKEDLAAFVEELEAVEAKEKQDDQMGPPGKGGKGKG
KKQMAEVLPSPSGKRVIPRVTIEMKAEAEKKIRRKIKNENTEGTSQENGMEPEGLKQRLE
KKLKSEPGTKTKKQTTLPFKPIKKGKQRNPNPWSDSESEASSKENDFDVSPRETEPQKAA
GTKKKKQTTLLLKPIQKRKQRHPWSDSESDVSSNENDFDVAPRETEPRRAAAKNKVIIDL
DSDEDFSDFDKESKEEDFVLSDASSIKTKTSPKRPNKEQMPQKRATAEIDLGAGDAQDDV
PLSPSSSAADFPDETEIIKPVSKKNVAVKKRAAKGQSSTSTTGAKKRAAPKGTKKDPGLN
SDAPQKPDSPKTKNRRKRKPSTSDDSDSNFEKMISKAVTSKKSKGDSDDLHLDLDSPVAP
RAKSGRAKKPIKYLEESDEDDLF
NT seq
4752 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactgcagcctgtaaacgaaaatatgcaaatgaacaaaacaaagaaa
aatgaagatgctaagaaaagactatctattgaaagaatctatcaaaagaaaacgcaattg
gaacatattctgctccgtccggacacctatattggctctgtggaattagtgacccagcaa
atgtgggtttatgatgaagatattggcatgaatttcagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgaaattctagtcaatgctgcagacaataaacaaagggatcca
aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaat
aatgggaaaggtattcctgttgttgaacacaaagttgagaaggtatatgttccagctctc
atctttggacagctcctaacttccagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaagtttactgtggaa
acagccactaaagaatacaagaaaatgttcaaacagacatggatggataacatggggaga
gctagtgagatggtactcaaaccctttagtggagaagattatacatgtgttaccttccag
cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcactaatggtt
agaagagcatatgatattgctggatccactaaagatgtcaaagtctttctcaatggaaat
aagcttccagtgaaaggattccgtagttatgtggatatgtatttgaaggataaagtagat
gaaactggtaatccgttgaaaataatccatgaacaagtaaaccacaggtgggaagtgtgt
ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcatcgctacttcc
aagggtggcagacatgttgattatgtaacggatcagattgtgactaaacttattgaagtt
gtgaagaagaagaacaagggtggcgttgcggtaaaggcacatcaggtgaaaaatcacgtg
tggatttttgtgaatgccttaattgaaaacccaacctttgactctcagacgaaagaaaac
atgactttacaagtcaagaactttggatccacatgccaattaagtgaaaaattcatcaaa
gctgcagtgggctgtggtattgtagaaagcatactaaactgggtgaagttcaaggctcaa
gcccaattaaacaagaagtgttcatctgtaaaacataacagaatcaagggaattcccaaa
ctggatgatgccaatgatgcagggggccgaaactccactgagtgtacgcttatcttgact
gagggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaaa
tatggggttttccctcttagaggaaaaatactcaatgttcgagaagcttctcataaacag
ataatggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcattgaagagtcttcgttatgggaagataatgattatgaca
gatcaggaccaagacggttctcatatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtg
tctaaaaacaagcaagaaatcgcattctatagtcttcctgaatttgaagaatggaagtgt
tctacaccgaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca
tcaaaagaagctaaggagtactttgcagatatgaaaagacatcgtatccgattcaaatat
tctggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactcatttcatggaggatagaagacaacggaagttatgtggcctt
cctgaggattacttgtatgggcaagctaccacttatctgacatacaatgacttcataaac
aaggaacttatcctgttttcaaattctgataatgagagatctatcccatctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacgtgtttcaaacggaatgacaagcgg
gaggtgaaggttgcccagttagctgggtcagtggctgagatgtcctcttatcatcatggt
gagatgtcattaatgatgaccattatcaatttggcccaaaattttgtgggtagcaataac
ctgaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagctctttggcccggttgttatttccacca
caagatgatcacacattaaagttcttatatgatgataaccaacgagtagagcctgaatgg
tacattcctattatacccatggtgctggtaaatggcgctgaaggaatcggtactgggtgg
tcctgcaaaatccccaactatgatattcgtgaaattgtgaataatatcaggcgtttgatg
gatggagaagaacctttgccgatgctgccgagttacaagaacttcaagggtactattgaa
gagctggctgcaaatcaatatgtgattagtggtgaagtggctattcttaattccacaacc
attgaaatctcagagcttcccgtcagaacatggacccagacatataaagaacaggttcta
gaacccatgttgaatggcactgagaagacacctcctctaataacggattacagggaatac
catacagataccactgtgaagtttattgtgaagatgactgaagaaaaactggcagaggcc
gagagagtgggactacacaaagtcttcaaactccaaactagtctcacgtgcaactctatg
gtgctttttgaccacgtaggctgtttaaagaaatacgacacagtgttggatattctaaga
gagttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
attggcgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatcgat
ggcaaaatagtcattgaaaacaagcctaagaaagaattaattaaagttctgattcagagg
ggatatgattcggaccctgtaaaggcttggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatggagagagcgacaatgaaaaggaaactgagaaaagtgactctgtaactgga
ccaacgttcaactaccttcttgatatgcctctttggtatctcaccaaggaaaagaaagat
gaactgtgcaaactgaaaaatgaaaaagagcaagagctagaaatattaaagagaaagagt
ccatcagatttgtggaaagaagacttggctgcttttgttgaagagctggaggctgttgaa
gccaaggaaaaacaagatgaccaaatgggacctcctgggaaaggggggaaaggaaagggg
aaaaaacaaatggctgaagttttgccttctccaagtggaaaacgagttatcccccgagtt
accatagagatgaaagcagaggcagaaaagaaaattagaaggaaaattaagaatgaaaat
actgaaggaacctctcaagagaatggtatggaaccagaaggcctaaaacaaagattagag
aagaaactgaaaagtgaaccaggtaccaagacaaagaaacaaactacattgccatttaaa
ccaatcaaaaaaggaaagcagagaaaccctaacccttggtctgattcagaatcagaagcg
agcagtaaagaaaatgattttgatgtctctccacgagaaacagagccacagaaagcagca
ggtaccaagaaaaagaaacaaactacattgctgcttaaaccaatccaaaaaagaaagcag
agacacccttggtctgattcagagtcagatgtgagcagtaatgaaaatgattttgatgtc
gctccaagagaaacagagccacggagagcagcagcaaaaaataaagtcataattgatttg
gattcggatgaagatttctcagattttgataaagaaagtaaagaggaagattttgtccta
tcggatgccagttcaattaagaccaagacttccccaaaacgtcctaacaaagaacagatg
ccgcagaagagagccacagcagaaatagaccttggtgctggtgatgcccaggacgacgtt
ccactttctccaagctcttctgctgctgatttcccagatgaaacggaaattataaaacct
gtttcgaagaaaaacgtggcggtgaagaagagggcggcaaaaggtcagtcttccacctcc
acaacaggtgccaaaaaaagggctgcaccaaaaggaaccaagaaggatccaggcttgaat
tctgatgcccctcaaaagcctgattcccccaaaaccaagaatcgccgcaaaaggaagcca
tccacgtctgatgattccgactctaattttgagaaaatgatttctaaagcagtcacaagc
aagaaatccaagggggacagtgatgacctccatctggacttagactctcctgtggctcct
cgggcaaaatctggacgggcaaagaaacccataaagtacctcgaagaatcagatgaagac
gatctgttttaa
DBGET
integrated database retrieval system
