KEGG   Rhinolophus ferrumequinum (greater horseshoe bat): 117013904
Entry
117013904         CDS       T07722                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
rfq  Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq04010  MAPK signaling pathway
rfq04015  Rap1 signaling pathway
rfq04218  Cellular senescence
rfq04380  Osteoclast differentiation
rfq04620  Toll-like receptor signaling pathway
rfq04664  Fc epsilon RI signaling pathway
rfq04668  TNF signaling pathway
rfq04750  Inflammatory mediator regulation of TRP channels
rfq04912  GnRH signaling pathway
rfq04935  Growth hormone synthesis, secretion and action
rfq04936  Alcoholic liver disease
rfq05014  Amyotrophic lateral sclerosis
rfq05022  Pathways of neurodegeneration - multiple diseases
rfq05132  Salmonella infection
rfq05135  Yersinia infection
rfq05145  Toxoplasmosis
rfq05161  Hepatitis B
rfq05163  Human cytomegalovirus infection
rfq05167  Kaposi sarcoma-associated herpesvirus infection
rfq05169  Epstein-Barr virus infection
rfq05170  Human immunodeficiency virus 1 infection
rfq05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rfq05417  Lipid and atherosclerosis
rfq05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rfq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    117013904 (MAP2K6)
   04015 Rap1 signaling pathway
    117013904 (MAP2K6)
   04668 TNF signaling pathway
    117013904 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    117013904 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    117013904 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    117013904 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    117013904 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    117013904 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    117013904 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    117013904 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    117013904 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    117013904 (MAP2K6)
   05161 Hepatitis B
    117013904 (MAP2K6)
   05163 Human cytomegalovirus infection
    117013904 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    117013904 (MAP2K6)
   05169 Epstein-Barr virus infection
    117013904 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    117013904 (MAP2K6)
   05135 Yersinia infection
    117013904 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    117013904 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    117013904 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    117013904 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    117013904 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    117013904 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    117013904 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rfq01001]
    117013904 (MAP2K6)
Enzymes [BR:rfq01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     117013904 (MAP2K6)
Protein kinases [BR:rfq01001]
 Serine/threonine kinases: STE group
  STE7 family
   117013904 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 117013904
NCBI-ProteinID: XP_032947355
Ensembl: ENSRFEG00010007955
UniProt: A0A671EJ41
LinkDB
Position
21:45917152..46016803
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSEQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLIIGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggcctgaaaatcccaaaggaagccttt
gaacaacctcagaccagttccacgccgcctcgagatttagactctaaagcttgcatttct
attggcaatcagaactttgaggtgaaggcagatgacctggagcctatcatggaactggga
cgaggtgcatatggggtcgtggagaagatgcgacacgtacccagtgagcagatcatggcg
gtgaagcgaatccgggccaccgtaaatagccaggagcagaaaaggctacttatggatttg
gatatttccatgaggacagtggactgcccttttactgtcaccttttatggtgcactcttc
cgggagggtgatgtttggatctgcatggagctcatggatacatcgctagataaattctac
aaacaagtgattgataaaggccaaacaattccagaggacatcttagggaaaatagcagta
tctattgtaaaagcattagaacatttacacagtaagctctctgtcattcatcgagatgtc
aagccttccaacgtgctgatcaatgctctgggccaagtgaagatgtgtgattttggaatc
agtggctaccttgtagactctgtggctaaaactattgatgcaggatgcaaaccatacatg
gctcccgaaagaataaacccggagctcaaccagaagggttacagtgtgaagtcggacatt
tggagtctgggcatcacaatgattgagttggccatccttcggtttccctatgattcgtgg
ggaactcctttccagcagctcaaacaggtggtagaggagccatcgccgcaactcccggca
gacaagttctccgaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggccaacatatccagagcttatgcaacacccatttttcaccctacatgaatccaaa
gcaacagatgtggcgtcttttgtaaaactgattattggagactaa

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