Rhinolophus ferrumequinum (greater horseshoe bat): 117017296
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Entry
117017296 CDS
T07722
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq01521
EGFR tyrosine kinase inhibitor resistance
rfq01522
Endocrine resistance
rfq01524
Platinum drug resistance
rfq04010
MAPK signaling pathway
rfq04012
ErbB signaling pathway
rfq04014
Ras signaling pathway
rfq04015
Rap1 signaling pathway
rfq04022
cGMP-PKG signaling pathway
rfq04024
cAMP signaling pathway
rfq04062
Chemokine signaling pathway
rfq04066
HIF-1 signaling pathway
rfq04068
FoxO signaling pathway
rfq04071
Sphingolipid signaling pathway
rfq04072
Phospholipase D signaling pathway
rfq04114
Oocyte meiosis
rfq04140
Autophagy - animal
rfq04148
Efferocytosis
rfq04150
mTOR signaling pathway
rfq04151
PI3K-Akt signaling pathway
rfq04210
Apoptosis
rfq04218
Cellular senescence
rfq04261
Adrenergic signaling in cardiomyocytes
rfq04270
Vascular smooth muscle contraction
rfq04350
TGF-beta signaling pathway
rfq04360
Axon guidance
rfq04370
VEGF signaling pathway
rfq04371
Apelin signaling pathway
rfq04380
Osteoclast differentiation
rfq04510
Focal adhesion
rfq04520
Adherens junction
rfq04540
Gap junction
rfq04550
Signaling pathways regulating pluripotency of stem cells
rfq04611
Platelet activation
rfq04613
Neutrophil extracellular trap formation
rfq04620
Toll-like receptor signaling pathway
rfq04621
NOD-like receptor signaling pathway
rfq04625
C-type lectin receptor signaling pathway
rfq04650
Natural killer cell mediated cytotoxicity
rfq04657
IL-17 signaling pathway
rfq04658
Th1 and Th2 cell differentiation
rfq04659
Th17 cell differentiation
rfq04660
T cell receptor signaling pathway
rfq04662
B cell receptor signaling pathway
rfq04664
Fc epsilon RI signaling pathway
rfq04666
Fc gamma R-mediated phagocytosis
rfq04668
TNF signaling pathway
rfq04713
Circadian entrainment
rfq04720
Long-term potentiation
rfq04722
Neurotrophin signaling pathway
rfq04723
Retrograde endocannabinoid signaling
rfq04724
Glutamatergic synapse
rfq04725
Cholinergic synapse
rfq04726
Serotonergic synapse
rfq04730
Long-term depression
rfq04810
Regulation of actin cytoskeleton
rfq04910
Insulin signaling pathway
rfq04912
GnRH signaling pathway
rfq04914
Progesterone-mediated oocyte maturation
rfq04915
Estrogen signaling pathway
rfq04916
Melanogenesis
rfq04917
Prolactin signaling pathway
rfq04919
Thyroid hormone signaling pathway
rfq04921
Oxytocin signaling pathway
rfq04926
Relaxin signaling pathway
rfq04928
Parathyroid hormone synthesis, secretion and action
rfq04929
GnRH secretion
rfq04930
Type II diabetes mellitus
rfq04933
AGE-RAGE signaling pathway in diabetic complications
rfq04934
Cushing syndrome
rfq04935
Growth hormone synthesis, secretion and action
rfq04960
Aldosterone-regulated sodium reabsorption
rfq05010
Alzheimer disease
rfq05020
Prion disease
rfq05022
Pathways of neurodegeneration - multiple diseases
rfq05034
Alcoholism
rfq05132
Salmonella infection
rfq05133
Pertussis
rfq05135
Yersinia infection
rfq05140
Leishmaniasis
rfq05142
Chagas disease
rfq05145
Toxoplasmosis
rfq05152
Tuberculosis
rfq05160
Hepatitis C
rfq05161
Hepatitis B
rfq05163
Human cytomegalovirus infection
rfq05164
Influenza A
rfq05165
Human papillomavirus infection
rfq05166
Human T-cell leukemia virus 1 infection
rfq05167
Kaposi sarcoma-associated herpesvirus infection
rfq05170
Human immunodeficiency virus 1 infection
rfq05171
Coronavirus disease - COVID-19
rfq05200
Pathways in cancer
rfq05203
Viral carcinogenesis
rfq05205
Proteoglycans in cancer
rfq05206
MicroRNAs in cancer
rfq05207
Chemical carcinogenesis - receptor activation
rfq05208
Chemical carcinogenesis - reactive oxygen species
rfq05210
Colorectal cancer
rfq05211
Renal cell carcinoma
rfq05212
Pancreatic cancer
rfq05213
Endometrial cancer
rfq05214
Glioma
rfq05215
Prostate cancer
rfq05216
Thyroid cancer
rfq05218
Melanoma
rfq05219
Bladder cancer
rfq05220
Chronic myeloid leukemia
rfq05221
Acute myeloid leukemia
rfq05223
Non-small cell lung cancer
rfq05224
Breast cancer
rfq05225
Hepatocellular carcinoma
rfq05226
Gastric cancer
rfq05230
Central carbon metabolism in cancer
rfq05231
Choline metabolism in cancer
rfq05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rfq05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
117017296 (MAPK1)
04012 ErbB signaling pathway
117017296 (MAPK1)
04014 Ras signaling pathway
117017296 (MAPK1)
04015 Rap1 signaling pathway
117017296 (MAPK1)
04350 TGF-beta signaling pathway
117017296 (MAPK1)
04370 VEGF signaling pathway
117017296 (MAPK1)
04371 Apelin signaling pathway
117017296 (MAPK1)
04668 TNF signaling pathway
117017296 (MAPK1)
04066 HIF-1 signaling pathway
117017296 (MAPK1)
04068 FoxO signaling pathway
117017296 (MAPK1)
04072 Phospholipase D signaling pathway
117017296 (MAPK1)
04071 Sphingolipid signaling pathway
117017296 (MAPK1)
04024 cAMP signaling pathway
117017296 (MAPK1)
04022 cGMP-PKG signaling pathway
117017296 (MAPK1)
04151 PI3K-Akt signaling pathway
117017296 (MAPK1)
04150 mTOR signaling pathway
117017296 (MAPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
117017296 (MAPK1)
04148 Efferocytosis
117017296 (MAPK1)
09143 Cell growth and death
04114 Oocyte meiosis
117017296 (MAPK1)
04210 Apoptosis
117017296 (MAPK1)
04218 Cellular senescence
117017296 (MAPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
117017296 (MAPK1)
04520 Adherens junction
117017296 (MAPK1)
04540 Gap junction
117017296 (MAPK1)
04550 Signaling pathways regulating pluripotency of stem cells
117017296 (MAPK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
117017296 (MAPK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
117017296 (MAPK1)
04613 Neutrophil extracellular trap formation
117017296 (MAPK1)
04620 Toll-like receptor signaling pathway
117017296 (MAPK1)
04621 NOD-like receptor signaling pathway
117017296 (MAPK1)
04625 C-type lectin receptor signaling pathway
117017296 (MAPK1)
04650 Natural killer cell mediated cytotoxicity
117017296 (MAPK1)
04660 T cell receptor signaling pathway
117017296 (MAPK1)
04658 Th1 and Th2 cell differentiation
117017296 (MAPK1)
04659 Th17 cell differentiation
117017296 (MAPK1)
04657 IL-17 signaling pathway
117017296 (MAPK1)
04662 B cell receptor signaling pathway
117017296 (MAPK1)
04664 Fc epsilon RI signaling pathway
117017296 (MAPK1)
04666 Fc gamma R-mediated phagocytosis
117017296 (MAPK1)
04062 Chemokine signaling pathway
117017296 (MAPK1)
09152 Endocrine system
04910 Insulin signaling pathway
117017296 (MAPK1)
04929 GnRH secretion
117017296 (MAPK1)
04912 GnRH signaling pathway
117017296 (MAPK1)
04915 Estrogen signaling pathway
117017296 (MAPK1)
04914 Progesterone-mediated oocyte maturation
117017296 (MAPK1)
04917 Prolactin signaling pathway
117017296 (MAPK1)
04921 Oxytocin signaling pathway
117017296 (MAPK1)
04926 Relaxin signaling pathway
117017296 (MAPK1)
04935 Growth hormone synthesis, secretion and action
117017296 (MAPK1)
04919 Thyroid hormone signaling pathway
117017296 (MAPK1)
04928 Parathyroid hormone synthesis, secretion and action
117017296 (MAPK1)
04916 Melanogenesis
117017296 (MAPK1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
117017296 (MAPK1)
04270 Vascular smooth muscle contraction
117017296 (MAPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
117017296 (MAPK1)
09156 Nervous system
04724 Glutamatergic synapse
117017296 (MAPK1)
04725 Cholinergic synapse
117017296 (MAPK1)
04726 Serotonergic synapse
117017296 (MAPK1)
04720 Long-term potentiation
117017296 (MAPK1)
04730 Long-term depression
117017296 (MAPK1)
04723 Retrograde endocannabinoid signaling
117017296 (MAPK1)
04722 Neurotrophin signaling pathway
117017296 (MAPK1)
09158 Development and regeneration
04360 Axon guidance
117017296 (MAPK1)
04380 Osteoclast differentiation
117017296 (MAPK1)
09159 Environmental adaptation
04713 Circadian entrainment
117017296 (MAPK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
117017296 (MAPK1)
05206 MicroRNAs in cancer
117017296 (MAPK1)
05205 Proteoglycans in cancer
117017296 (MAPK1)
05207 Chemical carcinogenesis - receptor activation
117017296 (MAPK1)
05208 Chemical carcinogenesis - reactive oxygen species
117017296 (MAPK1)
05203 Viral carcinogenesis
117017296 (MAPK1)
05230 Central carbon metabolism in cancer
117017296 (MAPK1)
05231 Choline metabolism in cancer
117017296 (MAPK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
117017296 (MAPK1)
09162 Cancer: specific types
05210 Colorectal cancer
117017296 (MAPK1)
05212 Pancreatic cancer
117017296 (MAPK1)
05225 Hepatocellular carcinoma
117017296 (MAPK1)
05226 Gastric cancer
117017296 (MAPK1)
05214 Glioma
117017296 (MAPK1)
05216 Thyroid cancer
117017296 (MAPK1)
05221 Acute myeloid leukemia
117017296 (MAPK1)
05220 Chronic myeloid leukemia
117017296 (MAPK1)
05218 Melanoma
117017296 (MAPK1)
05211 Renal cell carcinoma
117017296 (MAPK1)
05219 Bladder cancer
117017296 (MAPK1)
05215 Prostate cancer
117017296 (MAPK1)
05213 Endometrial cancer
117017296 (MAPK1)
05224 Breast cancer
117017296 (MAPK1)
05223 Non-small cell lung cancer
117017296 (MAPK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
117017296 (MAPK1)
05170 Human immunodeficiency virus 1 infection
117017296 (MAPK1)
05161 Hepatitis B
117017296 (MAPK1)
05160 Hepatitis C
117017296 (MAPK1)
05171 Coronavirus disease - COVID-19
117017296 (MAPK1)
05164 Influenza A
117017296 (MAPK1)
05163 Human cytomegalovirus infection
117017296 (MAPK1)
05167 Kaposi sarcoma-associated herpesvirus infection
117017296 (MAPK1)
05165 Human papillomavirus infection
117017296 (MAPK1)
09171 Infectious disease: bacterial
05132 Salmonella infection
117017296 (MAPK1)
05135 Yersinia infection
117017296 (MAPK1)
05133 Pertussis
117017296 (MAPK1)
05152 Tuberculosis
117017296 (MAPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
117017296 (MAPK1)
05140 Leishmaniasis
117017296 (MAPK1)
05142 Chagas disease
117017296 (MAPK1)
09164 Neurodegenerative disease
05010 Alzheimer disease
117017296 (MAPK1)
05020 Prion disease
117017296 (MAPK1)
05022 Pathways of neurodegeneration - multiple diseases
117017296 (MAPK1)
09165 Substance dependence
05034 Alcoholism
117017296 (MAPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
117017296 (MAPK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
117017296 (MAPK1)
04933 AGE-RAGE signaling pathway in diabetic complications
117017296 (MAPK1)
04934 Cushing syndrome
117017296 (MAPK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
117017296 (MAPK1)
01524 Platinum drug resistance
117017296 (MAPK1)
01522 Endocrine resistance
117017296 (MAPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rfq01001
]
117017296 (MAPK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
rfq03036
]
117017296 (MAPK1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
rfq04147
]
117017296 (MAPK1)
Enzymes [BR:
rfq01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
117017296 (MAPK1)
Protein kinases [BR:
rfq01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
117017296 (MAPK1)
Chromosome and associated proteins [BR:
rfq03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
117017296 (MAPK1)
Exosome [BR:
rfq04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
117017296 (MAPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
STATB_N
Haspin_kinase
FTA2
Kdo
Motif
Other DBs
NCBI-GeneID:
117017296
NCBI-ProteinID:
XP_032953232
Ensembl:
ENSRFEG00010017785
UniProt:
A0A671FW44
LinkDB
All DBs
Position
25:22855465..22943323
Genome browser
AA seq
360 aa
AA seq
DB search
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcggcggcgggcgcgggcccggagatggtccgcgggcaggtgttcgac
gtggggccgcgctacaccaatctctcgtacatcggcgagggcgcctacggcatggtgtgc
tctgcttatgataatgtcaacaaagttcgagtagctatcaagaaaatcagtccttttgag
caccagacctactgccagagaaccctgagggagataaaaatcttactgcgcttcagacac
gagaacatcattggaatcaatgatattattcgagcgccaaccatcgagcaaatgaaagat
gtatatatagtacaagacctcatggaaacagatctctacaagctcttgaagacacaacac
ctcagcaacgaccatatctgctattttctttaccagatcctcagagggttaaagtatatc
cattcagctaacgtactgcaccgtgacctcaaaccttccaacctgctgctcaacaccacc
tgcgatctcaagatctgtgattttggcttggcccgtgttgcagatccagaccatgatcac
acagggttcctgacggagtacgtagccacacgttggtacagggctccggaaattatgttg
aattccaagggctataccaagtccattgatatctggtctgtaggctgtattctggcagag
atgctctccaacaggcccatcttcccagggaagcattatctcgaccagctgaaccacatt
ctgggtattcttggatccccatcacaggaagacctgaattgcataatcaatttaaaagct
agaaactatttgctttctcttccacacaaaaataaggtgccatggaacaggctgttccca
aatgctgactccaaagctctggatttactggacaaaatgttgacctttaaccctcacaag
aggattgaagtagaacaggcactggcccacccatatctggagcagtattatgacccaagt
gatgagcccatcgctgaagcaccattcaagtttgacatggaattggacgacttgcctaag
gagaagctcaaggaactcatttttgaagagaccgctagattccagccaggatacagatct
taa
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