Rhinolophus ferrumequinum (greater horseshoe bat): 117019487
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Entry
117019487 CDS
T07722
Symbol
TSC2
Name
(RefSeq) tuberin isoform X1
KO
K07207
tuberous sclerosis 2
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq04072
Phospholipase D signaling pathway
rfq04115
p53 signaling pathway
rfq04140
Autophagy - animal
rfq04150
mTOR signaling pathway
rfq04151
PI3K-Akt signaling pathway
rfq04152
AMPK signaling pathway
rfq04211
Longevity regulating pathway
rfq04218
Cellular senescence
rfq04714
Thermogenesis
rfq04910
Insulin signaling pathway
rfq04919
Thyroid hormone signaling pathway
rfq05163
Human cytomegalovirus infection
rfq05165
Human papillomavirus infection
rfq05168
Herpes simplex virus 1 infection
rfq05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
117019487 (TSC2)
04151 PI3K-Akt signaling pathway
117019487 (TSC2)
04152 AMPK signaling pathway
117019487 (TSC2)
04150 mTOR signaling pathway
117019487 (TSC2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
117019487 (TSC2)
09143 Cell growth and death
04115 p53 signaling pathway
117019487 (TSC2)
04218 Cellular senescence
117019487 (TSC2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
117019487 (TSC2)
04919 Thyroid hormone signaling pathway
117019487 (TSC2)
09149 Aging
04211 Longevity regulating pathway
117019487 (TSC2)
09159 Environmental adaptation
04714 Thermogenesis
117019487 (TSC2)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
117019487 (TSC2)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
117019487 (TSC2)
05163 Human cytomegalovirus infection
117019487 (TSC2)
05165 Human papillomavirus infection
117019487 (TSC2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
rfq01009
]
117019487 (TSC2)
Protein phosphatases and associated proteins [BR:
rfq01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
117019487 (TSC2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Tuberin
DUF3384
Rap_GAP
Motif
Other DBs
NCBI-GeneID:
117019487
NCBI-ProteinID:
XP_032957118
Ensembl:
ENSRFEG00010021226
LinkDB
All DBs
Position
15
Genome browser
AA seq
1811 aa
AA seq
DB search
MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFVITAETLRELSGDSGLNNRIRV
IGQICEVAKTKKFEEHAVEALWKAVADLLQPEKPPEARHAVLALLKAIVQGQGDRLGVLR
ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDVGLSSEFLLVL
VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI
VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG
MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVTWDI
LLNIIERLLQQLQSLESPELKAIVHDLLTTVEELCDQNEFHGSQERYFELIERCADQRPE
SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRSEARSAVRIKVLDVLSFVLLINRQFY
EEELINTVVICQLSHIPEDRDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVIARSLS
PPPELEEREVAAYSASLEDVKTAVLGLLVILQTKLYALPASHAVRVYEMLVNHIHLHYKH
NYTLPIAGSIRLQAFDFLLLLRADALHRLGLPTKDGVVRFSPYCLCDYMEPERGSEKKAS
GPLSPPTGPPSPVPAGPTVRLGSLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYK
VLIFTSPCSVDQLSSALYSMLSGPKTLERLRGIPEGFSRTDLHLAVVPVLTALISYHNYL
DKARQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIMVKALPILVVKLTHISATASMA
IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
RLPFRKDFVPFITKGLRSNVLRSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS
PPVKEFKESSAADVFRCRSISVSEHVVRSRIQTSLTSSSLGSADENSMAQADDNLKNLHL
ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLITVTTSVGTGTRSL
LGLDSGELQGSPELSSDPSLHVRQTKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLRIG
ALDAPASHFPGGPTLPGPQTAPVSKPEKASAGTQLPVQKEKTNLAAYVPLLTQGWAEILV
RRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKERRDTALYKSLSMPTAG
SAKPPPPPRSNTVASFSSLYQSSCQGKLHRSISWADSAVVLEEGSPGEANLPVEPPELED
FEATLGTDRRCRGAGEYSRSSSTSSQEEKSFRAEDLASGGIPIEQAVASKAARPSVDLSF
QPSQPLSKSSSSPELQTLQDILGDPGDKSDVSRLSPEAKARSQSGILDGEGTSWSAPGEE
SRGPTQPEGPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRVERDSFKSRTGASNAEKVPG
INPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSN
SELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQ
AVFHIATLMPTKDGDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPL
DYECNLVSLQCRKDMEGLVDPSAAKIASDRNLPFVARQMALHANMASQVHHSRSNPTDIY
PSKWIARLRHIKRLRQRIREEAQYSNPSLPLMHPPGHAKTPAQAPAEPTHTYETGQRKRL
ISSVDDFTEFV
NT seq
5436 nt
NT seq
+upstream
nt +downstream
nt
atggccaagccaacaagcaaagattcaggcttgaaggagaagtttaagatccttttggga
ctgggaacgccaaggccgaatcccaggtctgcagagggcaaacagacggagtttgttatc
accgcggaaaccctgagagaactgagtggtgatagtggcctcaacaatcgtatccgggtc
atagggcagatctgtgaagtcgcaaaaacaaagaaatttgaagagcatgcagtggaagct
ctctggaaggccgttgcagacctgctgcagccagagaagccaccagaggcccggcacgcg
gtgctggctttgctgaaggccatcgtgcaggggcagggggaccgcttgggtgttctcagg
gccctcttcttcaaggtcatcaaggattacccgtccaatgaagacctccatgaaagactg
gaagttttcaaggccctcacggacaatgggagacacatcacctacttggaagaagaactg
gccgagtttgtcctgcagtggatggacgtcggcctgtcctcagagttccttctggtgctt
gtgaaccttgtgaaattcaacagctgttacctcgacgagtacatcgcatccatggtccac
atgatctgcctgctgtgtgtccagactgtgtcctctgtggacatagaggtctctctgcag
gtgctggacgctgtagtctgttacaactgcctaccagccgagagcctccccctgttcatc
gtcaccctctgccgcaccatcaatgtcaaggagctctgtgagccttgctggaagctgatg
cgtaacctcctgggcactcacctgggccacagtgccatctacaacatgtgccgaatcatg
gaggacagagcctacatggaagatgccccgctgctgagaggagccgtgttctttgtcggc
atggctctctggggagcccaccgactctattcgctcaagaactccccgacgtctgtgttg
ccgtcattttatgaggccatgacctgtccaaacgaggtggtgtcctatgagatcgtcctc
tccataaccagactcatcaagaagtacaggagggagctgcaggctgtgacctgggacatt
ctgctgaacattatcgagcgcctgcttcagcagctccagagcctggagagcccggagctc
aaggccatcgtccatgacctgctgactacagtggaagagctgtgtgaccagaacgagttc
cacggctcacaggagagatactttgagctcattgagagatgtgcagaccagaggcctgag
tcctccctcttaaacttaataacctacagagctcagtcaatccacccagcaaaggatggc
tggatccacaacctgcagttactgatggagagattcttcaggagcgaagctcgcagtgct
gtacgtatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacaggcagttctat
gaggaggagctgatcaacacggtggtcatttgccagctctcccacatccctgaggacaga
gaccaccaggtccggaagctggccacgcagttgctggtggacctggccgaaggctgtcac
acccaccacttcaacagcctgctggacatcatcgagaaagtgattgcccgttccctttct
ccaccccccgagctggaggaaagagaggtggcggcgtactcggcctccttggaggacgtg
aagactgccgtgctggggctgctggtcatccttcagaccaagctgtatgccttgcctgcc
agtcacgccgtgcgtgtgtacgagatgctggtcaaccacatccacctgcactacaagcac
aactacaccctgcccatcgccggcagcatccggctgcaggcctttgacttcctgctgctg
ctgcgggccgacgcactgcaccgcctcggcctgcccaccaaggacggggtcgtgcggttc
agcccttactgcctctgtgactacatggagccagagagaggctcggagaagaaggccagt
ggccccctgtcacctcctaccggaccgcccagccctgtgcctgcgggccccaccgtgcgg
cttggctctctgccctactccctgctcttccgtgtcctgctgcagtgtttgaagcaggag
acggactggaaggtgctgaagcttgtgcttagcaagctgcccgagtcgctgcgctacaag
gtcctcattttcacctctccgtgcagcgtcgaccagctgtcctccgccctctactccatg
ctttcaggtcccaagaccctcgagcggctccgaggcatcccggaggggttctccagaact
gacctgcatctggccgtggttcccgtgctgacagctttgatctcgtaccacaactacttg
gacaaagccagacagcgggagatggtgtactgcctggagcaaggcctgatctaccgttgt
gccagccagtgcgtggtggccctggccatctgcagcgtagagatgccggacatcatggtc
aaggccctgcccatcctggtcgtgaagctcacgcacatctcggccacggccagcatggcc
attccacttctcgagttcctgtcgactctggccaggctgcctcacctctacaggaacttc
gcagcagagcagtacgccagtgtgtttgccatctctctaccgtataccaacccctccaaa
ttcaatcagtacatcgtgtgcctggcccatcatgtcatagctatgtggttcattaggtgc
cgcctgcccttccggaaagactttgttccttttatcactaagggcctgcgctccaatgtc
ctccggtcttttgatgacacccctgagaaggacagcttcagagcacggagcaccagtctc
aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactct
ccacccgtcaaagaattcaaggagagctctgcagccgatgtcttccgatgccgcagcatc
agtgtgtctgaacatgtggtccgcagcaggatccagacgtccctcacgagctccagcttg
gggtctgcagatgagaattccatggcccaggctgacgacaacttgaaaaatctccacctg
gagctcacggaaacgtgtctggacatgatggccagatatgtgttctccaacttcacggcg
gtccccaagaggtcccccgtgggagagttcctcctggccggtggcaggaccaaaacttgg
ctggttgggaacaagctcattaccgtgacaacgagcgtgggcaccggaacccggtcgctg
ctgggcctggactcaggagagctacagggcagcccggagctgagctctgaccccagcctg
cacgtgaggcagacaaaggaggcaccagccaagctggagtcgcaggcggggcagcaggtg
tgccgcggggcccgggaccgtgtccgctccatgtctgggggccatggccttcgcattggt
gcactggacgctccagcctcccacttcccaggtggccccactttgccaggcccacagact
gcccccgtcagcaaacctgagaaggcctcagccggcacccagctcccggtgcagaaagag
aagacgaacctggcagcctacgtacccctcttgacccagggctgggcggagatcttggtc
cggaggcccacagggaacaccagctggctgatgagcctggagaacccactcagccccttc
tcctcggacatcaacaacatgccgctgcaggagctgtccaatgccctcatggccgccgag
cgcttcaaggagcgtcgcgacacggccctgtacaagtcgctgtccatgccgacggccggc
tcggccaagccccccccacccccacgttctaacacagtggcctctttctcctccctgtac
cagtccagttgccaaggaaagttgcacaggagcatttcctgggcagactctgcagtggtt
ctggaggagggaagtccaggcgaggctaatttgccggtggagcccccggagctggaggac
ttcgaggccacgctaggcacagacaggcgctgtcggggtgctggagagtacagcaggtcg
tcttccacctccagccaggaggagaagtcgttccgcgcagaggacctggcctctggtggg
atccccatcgagcaggctgtggcctccaaggccgcccggccctccgtggacctctccttc
cagccgtcacagcccctgagcaagtccagctcgtcgcctgaactgcagaccctgcaggac
atcctcggggaccctggggacaagtctgacgtcagccggctgagcccagaggccaaggcc
cgctcacagtcggggatcctggatggggaaggcacttcctggtcagcccccggcgaagag
agccggggccccacccagcccgagggtcccttgccttccagctgtccccgctcccccagc
ggcctgcggccccgaggctacaccatctccgattctgccccatcgcgcaggggcaagagg
gtggagagggactctttcaagagcagaacaggggcctccaatgccgagaaggtgccaggc
atcaaccccagcttcgtgtttctgcagctttaccattcgcctttctttggtgacgagtcc
aacaagccaatccttttgcccaatgagtccttcgagcgatcagtgcagctgcttgaccag
atcccgtcctacgacacgcataagattgccgtcctgtacgtgggagaaggccagagcaac
agtgagctcgccatcctgtccaacgagcacggctcctataggtacaccgagttcctgacg
ggcctgggcaagctcatcgagctcaaggactgccagccggacaaggtgtacctgggcggc
ctggacgtgtgcggcgaggacggccagttcacctactgctggcacgatgacatcatgcaa
gctgtctttcacatcgccaccctgatgcccaccaaggacggggacaagcaccgctgcgac
aagaagcgccacctgggcaatgacttcgtgtccattgtgtacaatgactctggcgaggac
ttcaagctgggcaccatcaaaggccagttcaactttgtccacgtgattatcacccccctg
gactatgagtgcaacctggtgtcgctgcagtgcaggaaagacatggagggccttgtggac
cccagtgcggcgaagatcgcgtccgaccgcaacctgcccttcgtggcacgccagatggcc
ctgcacgccaatatggcgtcgcaggtgcaccacagtcgctccaaccccaccgacatctac
ccgtccaagtggattgccaggctccgccacatcaagcggctccgtcagcggatacgtgag
gaagcccagtactcaaaccccagcctgcccctgatgcaccccccgggccatgccaaaacc
ccggcgcaggccccagccgagcccacgcacacctacgagaccggccagcggaagcgcctc
atctcctcggtggacgacttcaccgagtttgtgtga
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integrated database retrieval system
