Rhinolophus ferrumequinum (greater horseshoe bat): 117022939
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Entry
117022939 CDS
T07722
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq01521
EGFR tyrosine kinase inhibitor resistance
rfq01522
Endocrine resistance
rfq04010
MAPK signaling pathway
rfq04012
ErbB signaling pathway
rfq04014
Ras signaling pathway
rfq04062
Chemokine signaling pathway
rfq04068
FoxO signaling pathway
rfq04072
Phospholipase D signaling pathway
rfq04150
mTOR signaling pathway
rfq04151
PI3K-Akt signaling pathway
rfq04510
Focal adhesion
rfq04540
Gap junction
rfq04630
JAK-STAT signaling pathway
rfq04650
Natural killer cell mediated cytotoxicity
rfq04660
T cell receptor signaling pathway
rfq04662
B cell receptor signaling pathway
rfq04664
Fc epsilon RI signaling pathway
rfq04714
Thermogenesis
rfq04722
Neurotrophin signaling pathway
rfq04810
Regulation of actin cytoskeleton
rfq04910
Insulin signaling pathway
rfq04912
GnRH signaling pathway
rfq04915
Estrogen signaling pathway
rfq04917
Prolactin signaling pathway
rfq04926
Relaxin signaling pathway
rfq04935
Growth hormone synthesis, secretion and action
rfq05034
Alcoholism
rfq05160
Hepatitis C
rfq05161
Hepatitis B
rfq05163
Human cytomegalovirus infection
rfq05165
Human papillomavirus infection
rfq05200
Pathways in cancer
rfq05205
Proteoglycans in cancer
rfq05206
MicroRNAs in cancer
rfq05207
Chemical carcinogenesis - receptor activation
rfq05208
Chemical carcinogenesis - reactive oxygen species
rfq05210
Colorectal cancer
rfq05211
Renal cell carcinoma
rfq05213
Endometrial cancer
rfq05214
Glioma
rfq05215
Prostate cancer
rfq05220
Chronic myeloid leukemia
rfq05221
Acute myeloid leukemia
rfq05223
Non-small cell lung cancer
rfq05224
Breast cancer
rfq05225
Hepatocellular carcinoma
rfq05226
Gastric cancer
rfq05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
117022939 (SOS2)
04012 ErbB signaling pathway
117022939 (SOS2)
04014 Ras signaling pathway
117022939 (SOS2)
04630 JAK-STAT signaling pathway
117022939 (SOS2)
04068 FoxO signaling pathway
117022939 (SOS2)
04072 Phospholipase D signaling pathway
117022939 (SOS2)
04151 PI3K-Akt signaling pathway
117022939 (SOS2)
04150 mTOR signaling pathway
117022939 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
117022939 (SOS2)
04540 Gap junction
117022939 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
117022939 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
117022939 (SOS2)
04660 T cell receptor signaling pathway
117022939 (SOS2)
04662 B cell receptor signaling pathway
117022939 (SOS2)
04664 Fc epsilon RI signaling pathway
117022939 (SOS2)
04062 Chemokine signaling pathway
117022939 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
117022939 (SOS2)
04912 GnRH signaling pathway
117022939 (SOS2)
04915 Estrogen signaling pathway
117022939 (SOS2)
04917 Prolactin signaling pathway
117022939 (SOS2)
04926 Relaxin signaling pathway
117022939 (SOS2)
04935 Growth hormone synthesis, secretion and action
117022939 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
117022939 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
117022939 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
117022939 (SOS2)
05206 MicroRNAs in cancer
117022939 (SOS2)
05205 Proteoglycans in cancer
117022939 (SOS2)
05207 Chemical carcinogenesis - receptor activation
117022939 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
117022939 (SOS2)
05231 Choline metabolism in cancer
117022939 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
117022939 (SOS2)
05225 Hepatocellular carcinoma
117022939 (SOS2)
05226 Gastric cancer
117022939 (SOS2)
05214 Glioma
117022939 (SOS2)
05221 Acute myeloid leukemia
117022939 (SOS2)
05220 Chronic myeloid leukemia
117022939 (SOS2)
05211 Renal cell carcinoma
117022939 (SOS2)
05215 Prostate cancer
117022939 (SOS2)
05213 Endometrial cancer
117022939 (SOS2)
05224 Breast cancer
117022939 (SOS2)
05223 Non-small cell lung cancer
117022939 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
117022939 (SOS2)
05160 Hepatitis C
117022939 (SOS2)
05163 Human cytomegalovirus infection
117022939 (SOS2)
05165 Human papillomavirus infection
117022939 (SOS2)
09165 Substance dependence
05034 Alcoholism
117022939 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
117022939 (SOS2)
01522 Endocrine resistance
117022939 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
IQ_SEC7_PH
PH_19
RHG20_PH
PH_10
PH_13
Motif
Other DBs
NCBI-GeneID:
117022939
NCBI-ProteinID:
XP_032963085
Ensembl:
ENSRFEG00010002884
UniProt:
A0A671DSK5
LinkDB
All DBs
Position
6:41909465..42000162
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSATEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLISLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKPSDI
EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNDHFNKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEEEDKECLNQAITALMNLQGSMDRIYKQYSPRRRPGDSVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQIFDKEDTCEYKHAFELVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFDERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNAGRHGSTSGTLRGHPTPLEREPCKISFSRIAETEIESTA
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNTKFDDDPPAIPPRQPPPPKVKPRVPAPTGAFDGPL
HSPPPPPPRDPLPDTPPPVPFRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPPSTPSPRVPRRCHVLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggagcaagtacaccccaatctctcagct
actgaagagtctctctattatattgaagagttgatttttcagctgcttaataaattatgc
atggcacaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacagtctgccatagagaaacgaaaacgaaga
aatcctctcttactgcctgtggacaaaatccatccttcactgaaggaagttttagggtac
aaagtggactaccatgtgtccttatatattgtggctgtcctagagtatatctcagctgat
attttgaaattggctggtaattatgttttcaatattcgacattatgaaatatctcagcag
gacattaaagtatcaatgtgtgcggataaggttttgatggacatgtttgatcaggatgac
ataggtttgatttctctctgtgaagatgaacctagttcttcaggtgaattaaactattat
gaccttgtcagaactgaaattgcagaagaaagacagtatctgcgggaactaaatatgatt
ataaaagtgtttcgagaagcctttctttctgacaaaaagctgtttaaaccttccgacata
gaaaagattttcagtaacatttcagatatacatgagttgactgtaaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagtagtcctcatcccttagctggcagctgt
tttgaagacttggcagaagagcaagcgtttgatccttatgaaacattatcgcaggacatt
ctttcaccaaaatttaatgaccatttcaataagttgatggccagacctgccgtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctggtgccagtgtatcattgttggcactattttgaattattaaagcaattgaaagca
tgcagtgaagaagaagaagacaaagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagtatggaccgaatttacaagcagtattcacctcgacgccgacctggggat
tctgtttgccctttttataatcgccaattaagaagcaagcacctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacaatgttgtaat
gaatttattatggaaggtccgttgacaagaattggtgctaaacatgaacggcatattttt
ctctttgatggtttaatgattagctgcaaacccaaccatagccagtctcgccttccaggt
tacagtagtgccgaatacagattaaaagaaaaatttgtcatgagaaaaatacaaatattt
gataaagaagatacttgtgagtacaaacatgcttttgaattagtatccaaagatgaaaac
agcataatatttgctgctaagtctgctgaagagaaaaataattggatggcagcacttatt
tctcttcattatcgtagtactctagatcgaatgctagattcagtactattgaaagaagaa
aatgagcagccactgagattaccaagtcctgaagtatatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccatcattaaa
ggaggaactgtggtgaaattaattgaaaggttaacgtatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggca
gtagagaaaggcgagcagccaattagtgcagaccttaaaaggtttcgcaaggaatatgtc
caaccagtacaacttaggatcctaaatgtgtttcggcactgggttgaacaccatttttat
gactttgaaagagatttggagttgcttgaaagactagaatccttcatttcaagtgtaaga
ggaaaagccatgaagaaatgggtagagtcaattgctaagatcattaagaggaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccacctccgccaattgaa
tggcatatcagcagaccaggacaatttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctaacacttttggaatctgatctctacaggaaagttcaaccttct
gaacttgtaggaagtgtatggacgaaagaagataaagaaataaattctcccaatttatta
aaaatgattcgccacaccacaaatctcacgctctggtttgaaaagtgcattgtggaagca
gaaaattttgacgaacgggtggcagtactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtactggagatagtcagtgcagtaaattcagtgtca
gtatacagactagaccacacctttgaggcattacaggaaagaaaaaggagaattttggat
gaagctgtggaattaagtcaagatcactttaaaaaatacctagtaaagcttaagtcaatc
aatccaccttgtgtgcctttttttgggatatatttaacaaatattctgaagactgaagaa
gggaataatgattttttaaaaaagaaaggtaaagatttaatcaatttcagtaagaggagg
aaagtggcggaaattactggagaaattcagcagtatcagaatcaaccttattgtttacgg
atagaaccagaaatgaggcggttctttgaaaaccttaaccccatgggaaatgcttctgaa
aaagagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaactgtaaa
cagccacctcgatttcctaggaaatcaactttctccttaaaatctcctggaataaggcct
aatgcaggccgacatggctctacctcaggcactttacgaggtcatccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattgctgaaactgagattgaatcaacagca
tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacagttcctgtggcagcaatagcatctttgctcca
gttctcttgccacattcaaagtctttcttcagttcgtgtggtagtttacataaactaagt
gaagagccactgattcctcctcctcttcctcctcgcaaaaagtttgatcatgatgcttca
aattccaagggaaatacgaagtttgatgatgatccccctgctattccaccgagacaacct
cctcctccaaaggtaaaacccagagttcctgctcctactggtgcatttgatgggcctctg
cacagtccacctccgccaccgccaagagatcctcttcctgatacccctccaccggttccc
tttcggcctccagaacactttataaactgtccatttaatcttcagccacctccactggga
cacctgcacagagatccagactggttcagagacgttagtacgtgtccaaattcgccaaac
actcctcctagcacaccctctccaagggtgccacgtcgatgccatgtgctcagttctagt
cacaataatcttgctcatcctcaagctccccctgttccgccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttacaaacgagagctttcacaccccccattgtat
agactgcctttgctagaaaatgcagaaactcctcagtga
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