Rhinolophus ferrumequinum (greater horseshoe bat): 117025739
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Entry
117025739 CDS
T07722
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq00190
Oxidative phosphorylation
rfq01100
Metabolic pathways
rfq04714
Thermogenesis
rfq04723
Retrograde endocannabinoid signaling
rfq04932
Non-alcoholic fatty liver disease
rfq05010
Alzheimer disease
rfq05012
Parkinson disease
rfq05014
Amyotrophic lateral sclerosis
rfq05016
Huntington disease
rfq05020
Prion disease
rfq05022
Pathways of neurodegeneration - multiple diseases
rfq05208
Chemical carcinogenesis - reactive oxygen species
rfq05415
Diabetic cardiomyopathy
Module
rfq_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
117025739 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
117025739 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
117025739 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
117025739 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
117025739 (NDUFS1)
05012 Parkinson disease
117025739 (NDUFS1)
05014 Amyotrophic lateral sclerosis
117025739 (NDUFS1)
05016 Huntington disease
117025739 (NDUFS1)
05020 Prion disease
117025739 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
117025739 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
117025739 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
117025739 (NDUFS1)
Enzymes [BR:
rfq01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
117025739 (NDUFS1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
117025739
NCBI-ProteinID:
XP_032967768
Ensembl:
ENSRFEG00010011973
UniProt:
A0A671F3U2
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Position
8:26185602..26211717
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AA seq
727 aa
AA seq
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MLRIPVRRALVGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNVIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAVAGGLVDAEALVALKDLLNR
VDSDALCTEEVFPSAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSAVDLTYRYDHLGESPKVLQDIASGSHPFSQVLKEAKKPMVVLGSSA
LQRNDGAAILAAVSNIAQKIRMSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKN
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQASELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaaggatacctgtaagaagggccttagtaggcctttctaagtctccaaaaggatgt
gttcgaacaactgccacagcagcaagcaacttgattgaagtatttgttgatggtcaatct
gtcatggtggaaccgggaactaccgtcctccaagcttgtgagaaggttggcatgcagatc
cctcgattctgttaccatgaaaggttgtctgttgctggaaactgcaggatgtgccttgtt
gaaattgagaaagctcctaaggttgtagctgcttgtgctatgccagtaatgaaaggttgg
aatatcctgacaaactcagagaaatctaagaaagccagagaaggtgtgatggagttctta
ttagcaaatcacccgctggactgtcctatttgtgaccagggaggtgaatgtgatctgcag
gaccagtccatgatgtttggaagtgacaggagccgatttttagagggcaaacgtgctgtg
gaggacaagaacattgggccgttggtaaagaccatcatgactagatgtatacagtgtact
cgctgcatcaggtttgcaagtgagattgcaggagtagatgatttgggaacaacaggcaga
ggaaatgatatgcaagttggcacatacattgaaaagatgttcatgtctgaactgtctggg
aatgtcattgatatctgccctgtcggtgccctgacctctaaaccctacgcctttactgcc
cggccgtgggaaacaagaaagacagaatccattgatgtaatggatgcagtcggaagcaat
attgtggtaagcacaagaactggagaggtgatgaggattttgccaaggatgcatgaggac
atcaatgaagagtggatctctgataaaaccagatttgcctatgatgggctaaaacgtcaa
agacttaccgaaccgatggtcagaaacgaaaaggggcttttaacctatacctcctgggag
gatgcactctctcgtgtagctggaatgttgcagagttttcaaggcaaagatgtggccgca
gttgcaggtggtctggtggacgctgaagccctggtagcactcaaggacttgctgaataga
gtggactcggatgccctgtgcactgaggaggtcttcccgagcgcaggagctggcacagat
ttacgttctaattatcttcttaatactacaatcgctggtgtggaagaggcagatgttgtc
cttctggttggtacaaatccacgttttgaggcaccactttttaatgctagaattcgaaag
agctggctgcataatgacttaaaagtggcccttataggcagcgcagtggatctcacttac
agatacgaccacctgggagagtcccccaaagttcttcaagacattgcttcaggcagccat
ccattcagccaggtcctaaaggaagctaaaaaaccaatggtggttttaggcagttctgca
ctccaaagaaatgatggggcagcaattcttgcagctgtttccaacattgctcaaaagatc
cggatgagtagcggtgttactggtgactggaaagttatgaatatccttcataggattgca
agccaagtagctgccttagaccttggctataaacctggggtagaagcaattcggaagaac
cctcccaaagtgctgtttctcttaggagcagatggaggttgtatcactcgacaggatttg
ccaaaggattgtttcattatttatcaaggacatcatggtgacgttggagctcctatagct
gatgttattctcccaggcgctgcttacacagaaaagtctgctacttatgtcaatactgaa
ggccgagctcagcagactaaagtagcagtgacacctcctggtttggcaagagaagactgg
aaaattataagagcactctcggagatagcaggtataactcttccatatgatactctggat
caagtaaggaacagactggaggaggtctctcctaatcttgttcgatatgatgatgttgaa
ggagctaattatttccagcaagcaagtgagctctccaagctagtgaaccagcaacttctt
gctgatccccttgttccacctcagctaacaataaaagacttctacatgacagattcaatt
agcagagcttcacagacaatggccaaatgtgtcaaagctgtcacagagggtgcccaggca
gtagaggaaccatccatatgctga
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