KEGG   Rhinolophus ferrumequinum (greater horseshoe bat): 117028523
Entry
117028523         CDS       T07722                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
rfq  Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq01521  EGFR tyrosine kinase inhibitor resistance
rfq01522  Endocrine resistance
rfq04010  MAPK signaling pathway
rfq04014  Ras signaling pathway
rfq04015  Rap1 signaling pathway
rfq04066  HIF-1 signaling pathway
rfq04068  FoxO signaling pathway
rfq04081  Hormone signaling
rfq04114  Oocyte meiosis
rfq04115  p53 signaling pathway
rfq04150  mTOR signaling pathway
rfq04151  PI3K-Akt signaling pathway
rfq04152  AMPK signaling pathway
rfq04211  Longevity regulating pathway
rfq04213  Longevity regulating pathway - multiple species
rfq04510  Focal adhesion
rfq04550  Signaling pathways regulating pluripotency of stem cells
rfq04730  Long-term depression
rfq04750  Inflammatory mediator regulation of TRP channels
rfq04913  Ovarian steroidogenesis
rfq04914  Progesterone-mediated oocyte maturation
rfq04935  Growth hormone synthesis, secretion and action
rfq04960  Aldosterone-regulated sodium reabsorption
rfq05200  Pathways in cancer
rfq05202  Transcriptional misregulation in cancer
rfq05205  Proteoglycans in cancer
rfq05214  Glioma
rfq05215  Prostate cancer
rfq05218  Melanoma
rfq05224  Breast cancer
rfq05410  Hypertrophic cardiomyopathy
rfq05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rfq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    117028523 (IGF1)
   04014 Ras signaling pathway
    117028523 (IGF1)
   04015 Rap1 signaling pathway
    117028523 (IGF1)
   04066 HIF-1 signaling pathway
    117028523 (IGF1)
   04068 FoxO signaling pathway
    117028523 (IGF1)
   04151 PI3K-Akt signaling pathway
    117028523 (IGF1)
   04152 AMPK signaling pathway
    117028523 (IGF1)
   04150 mTOR signaling pathway
    117028523 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    117028523 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    117028523 (IGF1)
   04115 p53 signaling pathway
    117028523 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    117028523 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    117028523 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    117028523 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    117028523 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    117028523 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    117028523 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    117028523 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    117028523 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    117028523 (IGF1)
   04213 Longevity regulating pathway - multiple species
    117028523 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117028523 (IGF1)
   05202 Transcriptional misregulation in cancer
    117028523 (IGF1)
   05205 Proteoglycans in cancer
    117028523 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    117028523 (IGF1)
   05218 Melanoma
    117028523 (IGF1)
   05215 Prostate cancer
    117028523 (IGF1)
   05224 Breast cancer
    117028523 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    117028523 (IGF1)
   05414 Dilated cardiomyopathy
    117028523 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    117028523 (IGF1)
   01522 Endocrine resistance
    117028523 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:rfq04052]
    117028523 (IGF1)
Cytokines and neuropeptides [BR:rfq04052]
 Cytokines
  Growth factors (RTK binding)
   117028523 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 117028523
NCBI-ProteinID: XP_032973105
Ensembl: ENSRFEG00010012713
UniProt: A0A671F8X2
LinkDB
Position
10:16979084..17053359
AA seq 191 aa
MGKISSLPTQLFKCCFCDFLKVKVHIMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKYQPPSTNKKTKSQRRRKGGPKKRPGGWAKETPKEGTEASQQMKGKK
KEQRRETEARN
NT seq 576 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtaaaggtacacatcatgtcctcctcgcatctcttctacttggccttgtgcttgctc
accttcaccagctctgccacagctgggccggagacactctgcggggctgagctggtggac
gctcttcagttcgtgtgtggagaccggggcttttatttcaacaagcccacggggtatggc
tccagcagtcggagggcgcctcagacaggcattgtggacgaatgctgcttccggagctgt
gatctgagaaggctggagatgtactgtgcacccctaaagcctgccaagtcagcccgctcc
gtccgtgcccagcgccataccgacatgcccaaggctcagaagtatcagcccccatctacc
aacaagaaaacgaagtctcagaggagaaggaaaggtgggccaaagaaacgcccaggaggg
tgggccaaagaaacgcccaaggaggggacggaagcaagtcagcagatgaaaggaaagaag
aaagagcagagaagggagactgaagctagaaactga

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