Rhinolophus ferrumequinum (greater horseshoe bat): 117028583
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Entry
117028583 CDS
T07722
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq00260
Glycine, serine and threonine metabolism
rfq00630
Glyoxylate and dicarboxylate metabolism
rfq00670
One carbon pool by folate
rfq01100
Metabolic pathways
rfq01200
Carbon metabolism
rfq01230
Biosynthesis of amino acids
rfq01240
Biosynthesis of cofactors
rfq01523
Antifolate resistance
Module
rfq_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
117028583 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
117028583 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
117028583 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
117028583 (SHMT2)
Enzymes [BR:
rfq01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
117028583 (SHMT2)
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Gene cluster
GFIT
Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
117028583
NCBI-ProteinID:
XP_032973261
Ensembl:
ENSRFEG00010012928
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All DBs
Position
10:56279277..56284461
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AA seq
504 aa
AA seq
DB search
MLSFSLLWRAQPLQRCAQLVRMAVRCQHSEAAQTQTREATKAWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPKTGLIDYDQLAITARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAYLLADMAHISGLVAGKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGVRSVD
PKTGREIPYTFEDQINFAVFPSLQGGPHNHAIAAVAVALKQAGTPMFREYSLQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVKIGLEVKSKTAKLQDFKSFLLQDAETRQ
RLADLKQRVEQFARAFPMPGFEEH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgtccttctctttgctctggagggctcagcctctgcagagatgtgctcagctggtc
aggatggccgtaaggtgccaacacagtgaggcagcccagacccagaccagagaagcaacc
aaggcctggacaggccaggagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagggagaaggacaggcagtgtcgaggcctggaactcattgcctccgagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcagagggttat
cctggcaagaggtattatggaggagcagaggtagttgatgaaatcgagctgctgtgtcag
cgccgggccttggaggcctttgatctggatcctgcacaatggggagtcaatgtccagccc
tactccgggtccccagctaatctggccgcctacacggcccttctgcaacctcacgaccga
atcatggggctggacctgcctgacgggggccacctcacccatggctatatgtctgatgtc
aagcggatctcggccacatccatcttctttgagtctatgccctataagctgaaccccaaa
actggccttattgactatgaccagctggcaatcactgctcgacttttccgaccgcggctc
atcatagctggcaccagcgcctatgcccgcctcatcgactatgcccgcatgagagaggtg
tgtgatgaagtcaaggcatacctgctggcagacatggcccacatcagtggcctggtggct
ggcaaggtgatcccctcacctttcaagcatgcagatgttgtcaccactaccacccacaag
acccttcgaggggccaggtcaggactcattttctaccggaagggggtgcggtctgtggac
cccaagactggccgggagatcccttacacatttgaggaccaaatcaactttgctgtgttc
ccatccctgcagggaggcccccacaatcatgccattgctgcagtggctgtggctctaaag
caggctggcacccccatgttccgggagtactccctgcaggttctgaagaacgctcgggca
atggctgatgccctgctagagcgaggctactcactggtgtctggtggcactgacaaccac
ctagtgctagtggacctgcggcccaagggcctggatggggcccgggctgagcgggtgctg
gagctggtatccatcacagccaacaagaacacctgtcctggagaccgaagtgccatcaca
ccgggcggccttcggcttggggccccagccttgacctctagacagtttcgagaagatgac
ttccgaagagttgtggactttatagatgaaggcgtcaagatcggcttggaggtgaagagc
aagaccgccaaactccaggatttcaaatccttcctcctccaggatgcagaaacaagacag
cgactggctgacctcaagcaacgggtggagcagtttgccagggctttccccatgcctggt
tttgaagagcactga
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