KEGG   Rhinolophus ferrumequinum (greater horseshoe bat): 117029085
Entry
117029085         CDS       T07722                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
rfq  Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq01522  Endocrine resistance
rfq04010  MAPK signaling pathway
rfq04015  Rap1 signaling pathway
rfq04068  FoxO signaling pathway
rfq04071  Sphingolipid signaling pathway
rfq04114  Oocyte meiosis
rfq04148  Efferocytosis
rfq04218  Cellular senescence
rfq04261  Adrenergic signaling in cardiomyocytes
rfq04370  VEGF signaling pathway
rfq04380  Osteoclast differentiation
rfq04550  Signaling pathways regulating pluripotency of stem cells
rfq04611  Platelet activation
rfq04613  Neutrophil extracellular trap formation
rfq04620  Toll-like receptor signaling pathway
rfq04621  NOD-like receptor signaling pathway
rfq04622  RIG-I-like receptor signaling pathway
rfq04625  C-type lectin receptor signaling pathway
rfq04657  IL-17 signaling pathway
rfq04658  Th1 and Th2 cell differentiation
rfq04659  Th17 cell differentiation
rfq04660  T cell receptor signaling pathway
rfq04664  Fc epsilon RI signaling pathway
rfq04668  TNF signaling pathway
rfq04670  Leukocyte transendothelial migration
rfq04714  Thermogenesis
rfq04722  Neurotrophin signaling pathway
rfq04723  Retrograde endocannabinoid signaling
rfq04728  Dopaminergic synapse
rfq04750  Inflammatory mediator regulation of TRP channels
rfq04912  GnRH signaling pathway
rfq04914  Progesterone-mediated oocyte maturation
rfq04917  Prolactin signaling pathway
rfq04926  Relaxin signaling pathway
rfq04932  Non-alcoholic fatty liver disease
rfq04933  AGE-RAGE signaling pathway in diabetic complications
rfq04935  Growth hormone synthesis, secretion and action
rfq04936  Alcoholic liver disease
rfq05014  Amyotrophic lateral sclerosis
rfq05020  Prion disease
rfq05022  Pathways of neurodegeneration - multiple diseases
rfq05132  Salmonella infection
rfq05133  Pertussis
rfq05135  Yersinia infection
rfq05140  Leishmaniasis
rfq05142  Chagas disease
rfq05145  Toxoplasmosis
rfq05152  Tuberculosis
rfq05161  Hepatitis B
rfq05163  Human cytomegalovirus infection
rfq05167  Kaposi sarcoma-associated herpesvirus infection
rfq05169  Epstein-Barr virus infection
rfq05170  Human immunodeficiency virus 1 infection
rfq05171  Coronavirus disease - COVID-19
rfq05205  Proteoglycans in cancer
rfq05208  Chemical carcinogenesis - reactive oxygen species
rfq05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rfq05415  Diabetic cardiomyopathy
rfq05417  Lipid and atherosclerosis
rfq05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rfq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    117029085 (MAPK11)
   04015 Rap1 signaling pathway
    117029085 (MAPK11)
   04370 VEGF signaling pathway
    117029085 (MAPK11)
   04668 TNF signaling pathway
    117029085 (MAPK11)
   04068 FoxO signaling pathway
    117029085 (MAPK11)
   04071 Sphingolipid signaling pathway
    117029085 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    117029085 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    117029085 (MAPK11)
   04218 Cellular senescence
    117029085 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    117029085 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    117029085 (MAPK11)
   04613 Neutrophil extracellular trap formation
    117029085 (MAPK11)
   04620 Toll-like receptor signaling pathway
    117029085 (MAPK11)
   04621 NOD-like receptor signaling pathway
    117029085 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    117029085 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    117029085 (MAPK11)
   04660 T cell receptor signaling pathway
    117029085 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    117029085 (MAPK11)
   04659 Th17 cell differentiation
    117029085 (MAPK11)
   04657 IL-17 signaling pathway
    117029085 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    117029085 (MAPK11)
   04670 Leukocyte transendothelial migration
    117029085 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    117029085 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    117029085 (MAPK11)
   04917 Prolactin signaling pathway
    117029085 (MAPK11)
   04926 Relaxin signaling pathway
    117029085 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    117029085 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    117029085 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    117029085 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    117029085 (MAPK11)
   04722 Neurotrophin signaling pathway
    117029085 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    117029085 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    117029085 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    117029085 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    117029085 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    117029085 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    117029085 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    117029085 (MAPK11)
   05161 Hepatitis B
    117029085 (MAPK11)
   05171 Coronavirus disease - COVID-19
    117029085 (MAPK11)
   05163 Human cytomegalovirus infection
    117029085 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    117029085 (MAPK11)
   05169 Epstein-Barr virus infection
    117029085 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    117029085 (MAPK11)
   05135 Yersinia infection
    117029085 (MAPK11)
   05133 Pertussis
    117029085 (MAPK11)
   05152 Tuberculosis
    117029085 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    117029085 (MAPK11)
   05140 Leishmaniasis
    117029085 (MAPK11)
   05142 Chagas disease
    117029085 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    117029085 (MAPK11)
   05020 Prion disease
    117029085 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    117029085 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    117029085 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    117029085 (MAPK11)
   05415 Diabetic cardiomyopathy
    117029085 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    117029085 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    117029085 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    117029085 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    117029085 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rfq01001]
    117029085 (MAPK11)
Enzymes [BR:rfq01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     117029085 (MAPK11)
Protein kinases [BR:rfq01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   117029085 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo Cas_CT1975
Other DBs
NCBI-GeneID: 117029085
NCBI-ProteinID: XP_032973963
LinkDB
Position
10:435554..442221
AA seq 392 aa
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRVGAAGEGRAPAGPALRLLRSQPAVLQDLKPS
NVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTAVDIWSVGCIM
AELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLRSI
FCGANPLAVDLLGRMLVLDSDQRVSAADALAHAYFSQYHDPDDEPEAEPYDESVEAKDRT
VEEWKELTYQEVLSFKPPEPPQQPSGSLEIEQ
NT seq 1179 nt   +upstreamnt  +downstreamnt
atgtcgggtccgcgcgcaggcttctaccggcaggagctgaacaagaccgtgtgggaggtg
ccgcagcggctacaggggctgcgcccggtgggctcgggcgcctacggttccgtctgctcg
gcctacgacgcgcggctgcgccagaaggtggcggtgaagaagctgtcgcgccccttccag
tcactgatccacgctcggaggacgtaccgggagctgcggctgctcaaacacctgaagcac
gagaatgtcatcgggttgctggacgtcttcactcccgccacctccatcgaggacttcagc
gaagtgtacctggtgaccaccctgatgggagccgacctgaataacatcgtcaagtgccag
gcgctgagcgacgagcatgttcagttcctcgtgtaccagctgctgcgcgggctgaagtac
atccactcagcggggatcatccaccgggtaggtgccgcgggtgagggtcgggcccctgca
ggacccgcgctgcgcttgctgcgctcacagcccgccgtcctgcaggacctgaagcccagc
aacgtggcagtgaacgaggactgcgagctcaggatcctggacttcgggctggcgcgccag
gctgacgaggagatgaccggctacgtggccacgcgctggtaccgcgcacctgagatcatg
ctcaactggatgcactacaaccagacggcagtggacatctggtctgtgggctgcatcatg
gctgagctgctccaaggaaaagcccttttcccaggaaatgactacatcgaccagctgaag
cgtatcatggaagtggtgggcacaccgagccctgaggttctggcaaagatatcctccgaa
catgcccggacatacatccagtccctgccccccatgccccagaaggacctcaggagcatc
ttctgtggagccaaccccctggctgtggacctcctgggaaggatgctggtgctggacagt
gaccagagggtcagtgcagccgatgccctggcccacgcctacttcagccagtaccatgac
ccggatgatgagcccgaggccgagccctacgatgaaagcgttgaagcaaaggaccgcact
gtggaggagtggaaggagctcacctaccaggaagtcctcagctttaagcccccagagcca
ccacagcagccgtctggcagtctggagattgagcagtga

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