Rhinolophus ferrumequinum (greater horseshoe bat): 117033123
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Entry
117033123 CDS
T07722
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq00140
Steroid hormone biosynthesis
rfq01100
Metabolic pathways
rfq05215
Prostate cancer
Module
rfq_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
117033123 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
117033123 (SRD5A2)
Enzymes [BR:
rfq01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
117033123 (SRD5A2)
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GFIT
Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
Motif
Other DBs
NCBI-GeneID:
117033123
NCBI-ProteinID:
XP_032980978
Ensembl:
ENSRFEG00010015312
UniProt:
A0A671FB45
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Position
13:49925944..49979471
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AA seq
254 aa
AA seq
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MPLQCQQSPVLAGSVALAALGALLLYLGEPSGYGKYTGSPMPTATRLPARAAWFLQELPS
FVVPAGILVGQPRALFGPPETVLLGLFCAHYFHRTFVYSFLTRGRPFPVVLLFKGFVFCM
GNGLLQGYCLTYCAEYPAEWYTDIRFSLGVFLFILGMGINIHSDYILRRLRKPGEIIYKI
PQGGLFAYVSGANFLGEIIEWIGFALASWSLPALAFAFFSFCFLGLRAFHHHRFYLKIFE
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgccccttcagtgccagcagagcccggtgctggcaggcagtgtcgcattggccgccctg
ggggccctgctactgtacttgggagagccctccggctacgggaagtacacagggagccca
atgcccacggctacccgtctgccagcccgcgccgcctggttcctgcaggagctgccctcc
ttcgtggtaccggccgggatcctcgtcgggcagccccgcgctctctttggcccgcctgag
actgtgcttctgggcctcttctgcgcacattacttccacaggacatttgtttactcattc
ctcactagagggaggccttttccagtcgtgttacttttcaaaggcttcgtcttctgcatg
gggaatggactcctgcaaggctactgtctgacttactgtgctgaataccctgctgagtgg
tacacagacatacgatttagcctgggcgtcttcttatttattttgggaatgggaatcaac
attcatagtgactatatattgcgccgcctcaggaagcctggagaaatcatctataagatt
ccacaaggtggcttgttcgcatacgtttctggagccaatttccttggcgagatcattgaa
tggatcggctttgccctggccagttggtccctcccagcacttgcatttgcgtttttctca
ttttgtttccttgggctgcgagcttttcaccaccacaggttctacctcaagatctttgag
gactaccccaaatctcggaaagccctcattccattcatcttttaa
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