Rhinolophus ferrumequinum (greater horseshoe bat): 117035821
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Entry
117035821 CDS
T07722
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq00230
Purine metabolism
rfq00670
One carbon pool by folate
rfq01100
Metabolic pathways
rfq01523
Antifolate resistance
Module
rfq_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
117035821 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
117035821 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
117035821 (GART)
Enzymes [BR:
rfq01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
117035821 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
117035821 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
117035821 (GART)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_4
ATP-grasp_3
Dala_Dala_lig_C
RimK
ATP-grasp_5
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
117035821
NCBI-ProteinID:
XP_032985767
Ensembl:
ENSRFEG00010001125
UniProt:
A0A671DL15
LinkDB
All DBs
Position
2:complement(99451368..99479172)
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLVIGNGGREHALAWKLAQSNHVKQVLVAPGNAGTACSEKISNAAISISDHSALAQ
FCKDEKIEFIVVGPEAPLAAGIVGNLTSAGVKCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWRAFTKPKEAYSFIMSADFPALVVKASGLAAGKGVIVAKNKEEACQAVQEIMQDKAF
GAAGETIVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVPKDLLLKIKNTILQRTVDGMQQEGMPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSPPLWLENRTAITVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRENLISALEDAKKGLAVIKFEGAIYRKD
IGYRAIAFLQQPRGLTYKESGVDIAAGNMLVKRIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLACGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLSTTEAVIAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERIAEGDVVIGIASSGLHSNGFSLVRKIVAKSSLRYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVVLDAQTWRVPRIFSWLQQEG
QLSKEEMARTFNCGIGAALVVSKELTKQILKYIQQCQEEAWVIGNVVACPEGSPRVKVRH
LIEAMQTNGPKLQDGTMKNNFAVQTKKARVAVLISGTGSNLQALIASTQAPSSSAHIVVV
ISNKAGVAGLDKAARAGIPTRVINHKLYKSRVEFDTAIDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGANAHEQALDAGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVRLEENGKLCWAKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaattggcaatggaggaagagaacatgcactggcgtggaaa
cttgcacagtctaatcatgtcaaacaggtgttggttgccccaggaaatgcaggcactgcc
tgctctgaaaagatttcaaatgctgccatctccatcagtgatcacagtgctcttgctcag
ttctgcaaagatgagaaaatcgaattcatagttgttggaccagaggcacctctggctgct
ggaattgttgggaacctgacatctgcaggagtgaaatgttttggccccacagcagaggca
gctcagttagagtccagcaaaagatttgcaaaagaatttatggaccgacatggaatccca
actgcacaatggagagctttcaccaaacctaaagaggcctacagcttcattatgagtgca
gatttccctgctttggttgtgaaggccagcggtcttgcagctgggaaaggtgtgattgtt
gccaagaacaaagaagaggcctgccaagctgtgcaggagatcatgcaggataaagctttt
ggagcagctggagaaacaattgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctctgcttcactgatggaaggactgtggcccccatgcccccagcacaggaccataagcga
ttgctggaaggagatcacggccccaacacaggggggatgggagcctattgtccagcacct
caggttcctaaggatttgttgctaaaaattaaaaataccattcttcagcggacagtggat
ggcatgcagcaggagggtatgccatatacaggtattctctatgctggtataatgctgact
aaggatggcccaaaagttctggagtttaattgccgttttggtgatccagagtgccaggtg
atcctcccacttcttaaaagtgatctttacgaagtgattcagtctaccttagatggcctg
ctgtgcacctctccacccctttggcttgaaaaccgcactgccataactgttgtcatggca
agtaaaggttatccaggagactacaccaagggtgtggagatcacagggtttcctgaggct
caagctttaggactggaggtgttccaagctggtactgccctaaaagatggcaaagtggtg
actaatggtggtagagttcttactgtcacagccattcgggaaaatcttatctcagccctt
gaagacgccaagaaaggactagctgttataaagtttgagggagccatttacaggaaggac
atcggctatcgtgccatagctttcctgcagcagcccaggggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggtcaagagaattaaacctttagcaaaagcc
acctccagaccaggctgtgatgttgatctgggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcctgtggaacagatggcgttggaactaaattg
aaaattgcccagcagtgcaataaacatgataccattggtcaagatttggttgcaatgtgt
gtaaatgatattctggcccaaggggcagagcccctcttcttcctcgattacttttcctgt
ggaaaacttgacctcagtacgactgaagctgtcattgctggaatcgctaaagcttgcgga
aaagctggatgtgccctccttggaggtgaaacggcagaaatgcctgacatgtatcctcct
ggagagtatgacctagccggttttgccgttggtgccatggagcgggatcagaaactccct
cacctggaaagaatcgcggaaggggatgtcgttattggaatagcttcatctggtcttcac
agcaatggatttagccttgtgaggaaaattgtagctaaatcttcccttcggtactcctct
ccagcacctgatggctgtggtgaccagaccttaggggacttacttctaactccaaccaga
atctacagccattcactgttacctgtcttgcgttcaggacatgtcaaggcctttgcccat
atcactggtggaggattgctagaaaacatccccagagttctccctgagaaacttggggtg
gtattagatgcccagacctggagggtccccaggatcttttcatggttacagcaggaagga
cagctctctaaagaagaaatggccagaacatttaactgtggcattggggctgcccttgtg
gtatcaaaggaactgacaaagcagattctaaagtatattcagcagtgccaggaagaagcc
tgggtgattggcaatgtggtggcatgccctgaaggttctcctcgtgtgaaagtcaggcac
ctgattgaagccatgcaaacaaatggaccaaaattgcaggatggcaccatgaaaaataat
ttcgctgtccaaacaaaaaaggcaagagtagctgtcttaatatctggaacaggatcaaac
ctccaagctctcatcgccagcacacaggcaccaagtagctctgcgcacattgttgtcgtt
atctccaacaaagccggggtggctggcttagataaggcggccagagccggcattccgacc
agagtaattaatcataaattatataaaagtcgtgtagaatttgacactgcaattgaccaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatggaatgggaagatgctgaacatccacccttccttgctccct
tcttttaagggtgcaaatgcccacgagcaagccctggatgccggtgtcacagtaactggg
tgcactgtgcacttcgtagctgaagacgtagatgctggacagattatcttgcaagaagct
gttccagtgaagaggggtgacactgttgcaactctgtctgaaagagtgaaattagccgaa
cataaaatatttcccgcagccctccagctggtggccagtggaactgtacggcttgaagaa
aatggcaagctctgttgggccaaagaggaatga
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