Rhinolophus ferrumequinum (greater horseshoe bat): 117036671
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Entry
117036671 CDS
T07722
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
117036671 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
rfq03032
]
117036671 (TOP2B)
03036 Chromosome and associated proteins [BR:
rfq03036
]
117036671 (TOP2B)
Enzymes [BR:
rfq01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
117036671 (TOP2B)
DNA replication proteins [BR:
rfq03032
]
Eukaryotic type
DNA Topoisomerases
117036671 (TOP2B)
Chromosome and associated proteins [BR:
rfq03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
117036671 (TOP2B)
Centrosome formation proteins
Centriole proteins
117036671 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
117036671
NCBI-ProteinID:
XP_032987648
Ensembl:
ENSRFEG00010010294
LinkDB
All DBs
Position
17:23384035..23436807
Genome browser
AA seq
1620 aa
AA seq
DB search
MAKASGGGAGAGGNGALTWVTLFDQNNAVKKEESEAASRNDSSKKMSVERVYQKKTQLEH
ILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNM
TCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGR
NGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPD
LSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDET
GVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVSKLIEVVK
KKNKAGVSVKPFQVKNHMWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAA
SNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEG
DSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSY
DDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASK
NKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTSKEAREYFADMERHRILFRYAG
PEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKE
LILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQ
ALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARRLFPAMD
DNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDG
LDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEP
MLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVL
FDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGK
LTIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPDF
NYLLNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQE
REDILSGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKKKKG
DLDTTAVKVEFDEELSGTPVEGTGEEALIQSVPINKGPKPKREKKEPGTRVRKTPTSSGK
SSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDAD
DDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKGQDF
GNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTT
PKPKRTPKQKKIETINSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS
KTTSKKPKKTSFDQDSDMDIFPSDFASEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4863 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgagcggcggcggcgcgggagccggcggcaacggggcactgacctgggtg
actctttttgatcagaacaatgctgtaaaaaaagaagagtcagaagctgcaagcagaaat
gattcttcaaagaagatgtctgttgagagagtgtatcagaaaaagacacaacttgaacac
attctccttcgtcctgatacatacattgggtcagtggagccattgacacagctaatgtgg
gtgtatgatgaagatgtaggaatgaattgcagagaggttacttttgtgccaggtttatac
aagatctttgatgaaatcttggttaatgcagctgataataaacagcgggataagaacatg
acctgtattaaagtttctattgatcctgaatctaacattataagcatttggaataatggg
aaaggcattccagtagtagaacacaaagtagagaaagtttatgttcctgcattaattttt
ggacagcttttaacatccagtaactatgacgatgatgagaaaaaagtaacaggtggtcgc
aatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaactgct
tgcaaagaatacaaacatagttttaagcagacatggatgaataatatgatgaagacttct
gaagccaaaattaaacattttgatggtgaagattatacatgcataacattccaaccagat
ttgtccaaatttaagatggaaaaacttgacaaggatattgtggccctcatgaccagaaga
gcttatgatctggctggttcatgcaaaggggtcaaggtcatgtttaatggaaagaaattg
cctgtaaatggatttcgaagttatgtagatctttatgtgaaagacaaattggatgaaact
ggagtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctcacg
ttgagtgaaaaaggattccagcaaatcagctttgtaaatagtattgcaacaacaaaaggt
ggacggcacgtggattatgtagtagatcaagttgtcagtaaactgattgaagtagtcaag
aaaaagaacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccatatgtgggtt
tttattaattgccttatcgaaaatccaacttttgattctcagactaaagaaaacatgact
ctgcagcccaaaagttttgggtctaaatgccaactgtcagaaaaattttttaaagcagcc
tctaactgtggcattgtagaaagtatactgaattgggtgaaatttaaggcgcagactcag
ttgaacaagaagtgttcatcagtaaagtacagtaaaatcaaaggtattcccaaactggat
gatgccaatgatgctggtggcaaacattccctggagtgtacactgatacttacagaggga
gactctgccaaatcgctggctgtgtctggattaggtgtgattggtcgagacagatatgga
gtctttccactcaggggaaaaattcttaacgtacgggaagcttctcataaacagatcatg
gaaaatgcagaaataaacaatattattaaaatagttggtctacaatacaaaaaaagttat
gatgatgcagaatctctgaaaactttacgctatggaaagattatgattatgactgatcag
gatcaagatggttctcacataaaaggcctgcttattaatttcatccatcacaattggcca
tctcttttgaagcatggttttcttgaagagttcattactccaattgtaaaggcaagcaaa
aataagcaggaactttcattctacagtattcctgaatttgatgagtggaaaaaacatata
gaaaaccagaaagcctggaaaataaaatactacaaagggttgggtaccagtacatctaaa
gaagcaagggaatattttgctgatatggaaaggcaccgcatcttgtttagatacgctggt
cctgaagatgatgctgccattaccttggcattcagtaaaaagaagattgatgacagaaaa
gaatggttaacaaattttatggaagatcggagacagcgtaggttacatggcttaccagag
caatttttatatggtacagcaacaaagcatttgacgtacaatgatttcatcaacaaggaa
ttgattctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggcttt
aaaccaggccaacgaaaagttttatttacctgtttcaagaggaatgataaacgtgaagta
aaagttgcccagttggctggatctgttgctgagatgtctgcttatcatcatggagaacaa
gcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaacaacattaac
ttgcttcagcctatcggtcagtttggaactcggcttcatggtggcaaagatgctgcaagc
cctcgttatattttcacaatgttaagctctttagcaagacggctgtttcctgctatggat
gacaacctgcttaaattcctatatgatgataatcaacgcgtagagcctgagtggtacatt
cctataattcccatggttttaataaatggtgctgagggcattggtactggatgggcctgt
aaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagatggc
ttggatccgcatcccatgcttccaaactacaaaaacttcaaaggaacgatccaagaactt
ggtcaaaaccaatatgcagtcagtggtgaaatatttgtggtggatagaaacacagtagag
attacagagcttccagttagaacttggacacaggtatacaaagaacaggttttagaacct
atgctaaatggaacagataaaacaccagcattaatttctgattataaagaatatcatact
gatacaacggtgaaatttgtggtgaaaatgactgaagagaaactagcacaagcagaagct
gctggattgcacaaagtttttaaacttcaaactactcttacttgtaattccatggtactc
tttgatcatatgggatgtctgaagaagtatgaaactgttcaagacattttgaaagaattc
tttgatttaagattaagttattatggtttacgtaaggagtggcttgtagggatgttggga
gcagaatctacaaagcttaacaatcaagctcgtttcattttagagaagatacaagggaaa
cttactatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttat
gaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaagaa
acacaaaaccagcatgatgatagttcctctgattcaggaactccgtcaggccctgatttt
aattatcttttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactgatt
aaacagagagatgcaaaaggtcgagaggtcaatgatcttaaaagaaaatctccttcagat
ctttggaaagaagatttagcagcatttgttgaagaactggataaagtggaagcgcaagaa
cgagaagatattctctctggaatggctggaaaagcaataaaaggtaaagttggcaaacct
aaagtgaagaaacttcaattggaagagacaatgccctcaccttatgggaggagaatagta
cctgaaattactgctatgaaggcagatgccagtaaaaagttgttgaagaagaaaaagggt
gatcttgataccacagcagtaaaagtggaatttgatgaagaactcagtggaacaccagta
gaaggtacaggagaagaggcattgatacagtcagtgcctataaataaaggtcccaaaccc
aaaagggaaaaaaaggagcctggtaccagggtgagaaaaacacccacatcatctggtaaa
tctagtgcaaagaaagtgaagaaacggaatccctggtcagatgatgagtccaagtcagaa
agtgacttggaagaaacagaacctgtggttattccaagagattctctgcttaggagagcg
gctgctgaaaggcctaagtacacatttgatttctcagaagaagaagatgatgatgctgat
gatgatgatgacaataatgatttagaggaactgaaagtgaaagcatctcccataacaaat
gatggggaagatgaatttgttccttcagacggcttagataaagatgaatatacattttca
ccaggcaaatcaaaagctactccagaaaaatcttcgcatgacaaaaaaggtcaggatttt
gggaatcttttctcatttccttcatactctcagaagtcggaagatgattcagctaaattt
gacagtaatgaagaagattctgcttctgttttttcaccttcatttggtctgaaacaaaca
gataaagttccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagatacaacc
cctaagcccaagagaacccccaaacagaagaaaatagagactataaactctgactcagat
tcagaatttggcattccaaagaagactacaacaccaaaaggtaaaggccggggggcaaag
aaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaacatcc
aaaacaacaagcaagaaaccgaagaaaacgtcttttgatcaggattccgatatggacatc
ttcccatcagacttcgcttctgaaccaccttctctgccacggactggtcgggctaggaaa
gaagtaaaatattttgcagagtctgatgaagaagaagatgttgattttgcaatgtttaat
taa
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integrated database retrieval system
