Rhinolophus ferrumequinum (greater horseshoe bat): 117037866
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Entry
117037866 CDS
T07722
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq00310
Lysine degradation
rfq01100
Metabolic pathways
rfq05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
117037866 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
117037866 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
rfq03036
]
117037866 (DOT1L)
Enzymes [BR:
rfq01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
117037866 (DOT1L)
Chromosome and associated proteins [BR:
rfq03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
117037866 (DOT1L)
HMT complexes
Dot1-containing complex
117037866 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
117037866
NCBI-ProteinID:
XP_032990271
Ensembl:
ENSRFEG00010009913
LinkDB
All DBs
Position
18:complement(61025075..61079900)
Genome browser
AA seq
1727 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ENKAAAPADTPVDSGAEEEKVGTTAIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKSPTALDLLRAQTVSQTAAASPQDAYKSPHSPFYQLPPSVQRQPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLDKDTRELRTQSLQLL
KARCEELKLDWSTLSLESLLKEKQALRSQISEKQRRCLELQISIVELEKSQRQQELLQLK
SCVPPDDAVPGHLRGKGGLGRELEAEPGRLHLELDCSKLSLPHFSSMSPELSMNGHAASY
ELCSALSRPSSKQNTPQYLASPLDQEVVPCTPGHSSRPRLERLSGLALPDYTRLSPAKLV
LRRHLSQDHAASSKAATGELHPRAEHTKENGLPYQSPGLTNGIKLSPQDPRPLSPVALQM
TGEKGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPVPQARESSSTLEKQMGANAHSSGSKGLALAPAGFSYTGSLAISGALAGSPAPLAPGA
EPPAFDESSSSGSLFATMGSRSSTPQHPPLLAQPRNSGPASPAHQLCASPRLGTAQGPLP
DASKGDLPSEAGFSDPESEAKRRAIFTISASTSSTKQSPSNKHSPLPVGTRGDSSQSHGQ
DSRKRGRRKRASAGTPSLSSGVSPKRRALPSVASLFTQSSGSPLNLNSMVNNINQPLEIT
AISSPESSLKSSPVPYQDNDQPPVLKKEKPLNQTNGAHYSPLTSDEEPGSEDEPGSARIE
RKIATISLESKSPPKTLENGGGLVGRKPLPASEPVNSSKWKATFSPISDLGLAKATDSPL
QASSALSQNSLFAFRPALEEPGSADAKLAAHPRKSFPGALSGAGGLSPSSNPPNGFAFSG
GLATDLSLHSFNDGASLSHKAPETASLGTPLSFPAPRGKEGGTEPSPFVNKRQLDGLGGP
KGEGGKGREAELGLPSCTPTDKASLAHVKAGKGRDREPDFKNGHNLFISAATVPPGGLLS
GPGLATAASSAGSVAPSAQTHRPFLGTFAPGPQFSLGPVSLQANLGSSVLQSLFSSVPAA
AGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPSASAHPFGASFGSGAACRSA
TLSLTPLQAVASTPASSFQAPPSMEPRPPLPPPAPPLGRPPAGPPALHAPPPPNAALPPV
PALLPANSEPALLQNLAPLPANQAFLPASSAASLPPANASLSIKLASLPHKASRPSFTVH
HQPLPGLTLAQAAPVIPQASSTGPSAVWVSLGMPPPCAARLTGVKPR
NT seq
5184 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccatgatgctgctcatgagatcattgagacc
atccgatgggtctgtgaggaaatcccagacctcaagctcgctatggagaattacgtccta
atcgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgacaagtacaaccgg
gccattgacagcatccaccagctgtggaagggcaccacgcagcccatgaagctgaacacg
cggccgtccaacggtctcctgcggcacatcctgcagcaggtctacaaccactcggtgaca
gaccctgaaaagctcaacaactacgagcccttctccccggaggtgtacggggagacctcc
ttcgacctggtcgcacagatgattgacgagatcaagatgactgaggacgacttgtttgtg
gacctgggcagtggagtgggccaggtcgtgctgcaggtcgccgcggccaccaactgcaaa
catcactacggcgtcgagaaagccgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtacggaaaaaagcatgcagaatacacactggaaaga
ggcgatttcctctcggaagagtggagagagcggatcgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaacatg
aaggaaggtggcagaatcgtgtcctcgaagcccttcgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtggtggagctgtcaccgctgaag
ggctcggtgtcatggacggggaagccagtgtcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgagaaaacaagagtaacacgaccacccccacgaaggtgcct
gagaacaaggcagctgcacctgcggacacccctgtggattctggtgctgaggaagagaaa
gtggggactaccgccatcaagaagccatccccctccaaagcccggaaaaagaagctgaac
aagaaggggcggaagctagccggccggaagcgcgggcgccccaagaagatgagcactgca
aaccctgagcgtaagcccaaaaagagcccgactgcactggacctgctgcgtgcccagact
gtgtcccagacggctgccgcgtcgccgcaggatgcatacaagtcacctcacagcccgttt
tatcagctacctcccagcgtgcagcggcagccgcctgaccagctgctgctggcacccacc
ccgcctgcactgcagaagctgctagaatccttcaagattcagtacctgcagttcctggca
tacaccaagacccctcagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaacgcccgcttgttgggcgctgcacagcagctgtttggccactgccaggcccagaaa
gaggagatcaagaggcttttccagcagaaactggatgagttgggagtgaaggccctgacc
tacagcgacctgatccaggcgcagaaggagatctcggctcacaaccagcagctgcgggag
cagacggagcagctagacaaggacacccgggagctgcgcacccagagcctccagctgcta
aaggctcggtgtgaggagctgaagctggactggtctacgctgtccctggagagcctgctg
aaggagaagcaggccctgaggagccagatctccgagaagcagagacgctgcctggagctg
cagatcagcattgtggagctggagaagagccagcggcagcaggagctcctgcagctcaag
tcctgtgtgccacccgacgacgctgtgcctggtcaccttcgcgggaagggcggcttgggc
cgtgagctggaggcggagcccggccggctgcacctggaactggactgctccaagctctca
ctgccccacttcagtagcatgagcccggagctctccatgaatggccatgcagccagctat
gagctctgcagtgcactgagccggccctcgtccaagcagaacaccccccagtacctggcc
tcaccgctggaccaggaggtcgtgccctgcacccctggccacagcagccggccccgtctc
gagaggctatcaggcctggccctgcccgactacaccaggctctcacctgccaagctggta
ctcagacgccacctgagccaggaccatgcggccagcagcaaggctgccaccggcgagctg
cacccacgagccgagcataccaaggagaacggccttccataccagagcccaggcctcacc
aatggcatcaagctgagccctcaggacccacggcccttgtcccccgtggccttacagatg
acaggagagaagggcagcgagaagggtctgaaggagcgcgcctacgccagcagcggggag
gccatcaccagcctgcctgtcagcatcccactcagcaccgtgcagcccagcaagctgccc
gtcagcatccctctggccagcgtggtgctgcccagccgtgccgagaaggtgagaagcacc
cccagccctgtgccgcaggcacgagagtcatcgtccacacttgagaagcagatgggtgct
aatgcccacagttctgggagcaaaggcctcgcccttgcccccgcaggcttctcctacact
ggctcattggccatcagcggggccctggcaggcagcccggccccgctcgctcctggagcc
gagccccccgcctttgacgagtcctctagctcggggagcctcttcgccaccatgggctcc
cgcagctcgaccccgcagcatcccccactgctggcacagccccggaactctggcccggcc
tcacctgcccaccagctgtgcgccagcccccggctgggcaccgcccagggcccgctccct
gatgccagcaaaggggaccttccctccgaggctggcttctcagatccagagagcgaggcc
aagaggagggccatcttcaccatctcagccagcaccagcagcaccaaacagtcgccttcc
aacaagcacagcccactgccggtgggcacccgcggggacagcagccagagtcacgggcag
gacagccgcaagcggggcaggaggaagcgggcgtcggcagggacccccagcctgagctcg
ggcgtgtcccccaagcgccgggccctgccatccgtcgccagcctcttcacgcagtcttca
ggatcccctctcaacctcaactccatggtcaacaacatcaaccagcctttggaaatcacg
gccatctcatcccccgagagctccctgaagagctctcctgtcccttaccaggacaatgac
cagccacccgtgctcaagaaagagaagcccctgaaccagaccaacggagcccactattcc
ccactgacctcggatgaggagccgggctctgaggacgagccgggcagcgccagaattgag
agaaaaattgccacgatctccttggaaagcaaatctcctccgaaaaccttggaaaatggt
ggtggcctggtgggaagaaagccactgcccgccagcgagcctgtcaacagcagcaagtgg
aaggccaccttctcgcctatctccgacctcggcctggccaaggccaccgacagcccattg
caggccagctccgctctgagccagaactccctatttgctttccggcctgccctggaggag
cccggctcggccgacgccaagctggctgcccaccccaggaagagctttcccggtgccctg
tcaggggccggtgggctgagcccaagcagcaaccctcccaacggcttcgccttcagcggg
ggcctggccactgacctcagtttacacagcttcaacgatggtgcttctctctcccacaag
gcccccgagacggccagcctgggcactcccttgagctttcccgccccacggggcaaggag
ggcggcacagagcccagcccctttgtgaacaagaggcagctggacggactgggaggccca
aagggcgaggggggcaagggcagggaggcagagttgggcctgccctcttgcacgcccacg
gacaaggcctcgctggcacacgtcaaggcgggcaagggccgggaccgcgagcctgacttc
aagaatggccacaacctcttcatttccgccgccaccgtgccccccgggggccttctcagt
ggcccgggccttgccacggcagcatcttcggcgggcagtgtggccccctctgcccagaca
caccggcccttcctgggcaccttcgcccccggcccgcagttctccctgggccccgtgtcc
ctgcaggccaacctgggctcatcagtgctgcagtctctgttcagctccgtgccggccgcc
gccggcctggtgcacgtctcgtccgctgcgaccagactgaccaactcacacgccatgggc
agcttttcctccggggtggcaggcggcgcagttggaggtgtctttaaccacgcggtgcct
tccgcctccgctcatccgtttggagccagtttcggcagcggggctgcgtgtcgcagcgcc
acgctgagcttaaccccgctgcaggcggtggccagcacccccgcctcttcctttcaggcc
ccgccctccatggagccgaggccgcccctacccccgcctgctccgcccctgggccggccc
cctgcgggaccgcccgccctccacgccccccctcctcctaacgccgccttgcctcccgtt
cccgcgctgctccccgctaactctgagcccgcgctcctgcagaacctggcgcccctccct
gctaaccaagctttcttacccgcctcctctgccgcctctctgccgcctgctaacgcctct
ctgtccatcaagctcgcctccctcccgcacaaggcctcccgcccctccttcacagtgcac
caccagcccctgcctgggctgaccctggcccaggctgctcctgtgatcccacaggccagc
tccacggggccgtccgctgtgtgggtttcccttggcatgccgcctccttgtgccgcgcgc
cttacgggggttaagccgcgataa
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integrated database retrieval system
