Rhodococcus sp. B7740: NY08_4751
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Entry
NY08_4751 CDS
T03776
Name
(GenBank) Uroporphyrinogen-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
rhb
Rhodococcus sp. B7740
Pathway
rhb00860
Porphyrin metabolism
rhb01100
Metabolic pathways
rhb01110
Biosynthesis of secondary metabolites
rhb01120
Microbial metabolism in diverse environments
rhb01240
Biosynthesis of cofactors
Module
rhb_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
rhb_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
rhb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NY08_4751
Enzymes [BR:
rhb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
NY08_4751
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
NY08_4751
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AJW42751
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Position
4826959..4828521
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AA seq
520 aa
AA seq
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MSPVRKNTNGRILFVGSGPGDPALLTVRAREVLGAAELAFTDPDVDKGVTALVGADVPRD
AETGENGVEVRPALGEPAEVAKTLLAEAKNGHDVVRLVSGDPLTTDSVIAEVSAVARTHV
PFEVLPGLPAGSAVPSYAGMALGSGHTEADVRGEVDWAALAAAPGPLVLHATSGHLAETA
SALVEHGLAPQTPAAITVRGTTRQQRTVEATLATLNDAGSELVGSLVVTVGKVVSGRNKM
SWWESRALYGWTVLVPRTKDQAGEMSDRLVTHGAIPIEVPTIAVEPPRSPAQMERSVKGL
VDGRYQWVVFTSTNAVRAVWEKFEEFGLDARAFSGVKIACVGEATAAKVRSFGINPELVP
SGEQSSLGLLEDFPPYDEVFDPVNRVLLPRADIATETLAEGLRERGWEIDDVTAYRTVRA
APPPAETREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPKTAETAVEFGLR
VDVQPESAQVGPLVEALAEHAARLRAEGALPPPRKKSRRR
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgagcccagtccgcaagaacaccaacggacggatcctgttcgtgggatccgggccgggt
gacccggctctgctcacggtccgggcacgggaagtgctcggagcggccgagctcgcattc
accgatcccgacgtcgacaagggcgtcacagcgctcgtcggtgccgatgtccccagggac
gcggagacgggcgagaacggtgtcgaggttcgtccggcactcggtgagcctgccgaggtc
gccaaaacgcttctcgccgaagccaagaacggccacgacgtggttcgcctggtctccggt
gatccgctcacgaccgactcggtgatcgccgaggtcagtgctgtcgctcgcacccacgtg
ccgttcgaggtgcttcccggcctgcccgcaggatcggccgtccccagctacgccggaatg
gcactcggttcgggtcacaccgaggccgatgtccgcggcgaggtcgactgggcagcgctc
gctgctgctcccggcccgctggtgctgcacgcgacgtcgggtcacctggccgaaaccgcc
agtgccctcgtcgaacacggattggcaccgcagacgcctgcagccatcaccgttcgtggc
accacccgtcagcagcggacggtcgaggccaccctcgccaccctgaacgacgccggatcc
gagctcgtcggttccctcgtcgtcaccgtgggcaaggtcgtctcgggccgaaacaagatg
tcctggtgggaatctcgtgcactgtacggctggaccgtgctggtgccgcgcaccaaggac
caggccggcgagatgagcgatcgcctcgtcacccacggagccatccccatcgaggttccg
accatcgccgtcgagcccccgcgcagcccggcccagatggaacggtccgtcaagggcctg
gtcgacggtcgataccaatgggtcgtcttcacctccaccaacgccgtgcgcgccgtgtgg
gagaagttcgaggagttcggtctcgacgctcgcgcgttctccggcgtcaagatcgcgtgt
gtcggtgaagcaaccgcggcgaaggtgcgttcgttcggcatcaaccccgagttggtgccg
tcgggtgagcagagctcgctcggactgctcgaagacttcccgccgtacgacgaggtgttc
gacccggtcaaccgagtccttcttccccgcgccgacatcgccaccgaaaccctcgccgag
ggtctgcgtgagcgcggctgggaaatcgacgacgtcaccgcgtaccgcaccgtccgggca
gcaccgccccccgccgagacccgcgagatgatcaagaccggcggcttcgacgcagtgtgc
ttcacgtcgagctccaccgtccggaacctggtcggcatcgccggaaagccgcacgctcgt
accctggtggcgtgcatcggccccaagaccgccgagacggccgtcgaattcggtctgcgc
gtggatgtgcagcccgagtcggcacaggtcggaccgctggtcgaggctctcgccgagcac
gcggcccgcctgcgggccgagggcgcactgcccccgccgcgcaagaagtcgcgccgccgg
taa
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