Rodentibacter caecimuris: FEE42_00225
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Entry
FEE42_00225 CDS
T06473
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
rhey
Rodentibacter caecimuris
Pathway
rhey00270
Cysteine and methionine metabolism
rhey00480
Glutathione metabolism
rhey01100
Metabolic pathways
rhey01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
rhey00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
FEE42_00225 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
FEE42_00225 (gshAB)
Enzymes [BR:
rhey01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
FEE42_00225 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATPgrasp_ST
ATP-grasp_3
GARS_A
Dala_Dala_lig_C
GSH-S_ATP
GCS2
DEAD
Motif
Other DBs
NCBI-ProteinID:
QIA75903
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All DBs
Position
48784..51063
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AA seq
759 aa
AA seq
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MNIQNIIKQHHLELLFQQGLFGIEKESQRVYADGSIVTTEHPKAFGNRSFHPYIQTDFAE
SQLELVTPPSKTLENALRWLSAIHEVTLRTLPENEYIFPFSMPAGLPPEKQIKVAQLDNP
EDVAYREHLVKNYGKYKQMVSGIHYNFQLDPAFVQALFEAQTKQTSAVDFQNDLYLKIAK
NFLRYQWILLYLFSATPTVDENYFRDGTPLQPNQYVRSLRSSPFGYVNEPEIKVSFNSLQ
SYVDSLEHWVNSGKLIAEKEFYSNVRLRGAAKARDLLKTGIQYLEFRLFDLNPFAPYGIT
LEDAKFIHYFILLMAWLDHTADQGDIELGKTRLAEVSWEDPLSPTAYAVEGELVLLQMLN
MLEALQAGDEIKAIAKEKFVQFANPRDTLCANVVVAIDQFGGYQKLGADIAKGNKKNAFE
RFYALSGFDNMELSTQALIFDAIQKGLKLEILDERDQFLSLQYGDHLEYVKNGNMTSHDR
YISPLIMENKVVTKKVLAKAGFNVPQSVEFTDVKSAVESFPLFENRAVVIKPKSTNFGLG
ITIFQQGVQNRDDFAKAVEIAFREDNEIMIEDYLVGTEYRFFVLGGQTLAVLLRVPANVV
GDGEHTVKELVEMKNDHPLRGDGSRTPLKKIALGDIEKLQLKEQGWTVDSIPPRDLIVQL
RANSNISTGGDSIDMTEQMHESYKQLAVGIAKAMGAAVCGVDLIIPDLTKPAENNLQSWG
VIEANFNPMMMMHIFPYAGKSRRVTLNVLEMLFPELKVR
NT seq
2280 nt
NT seq
+upstream
nt +downstream
nt
atgaatatccagaacataattaaacaacatcatcttgaattacttttccaacaaggttta
ttcggtattgaaaaggaaagccagcgtgtttacgcagacggttctattgtcaccaccgaa
catccgaaagcctttggtaatcgtagttttcatccttatattcaaacggattttgctgaa
agccaactggagctggttacgccgccgagtaaaacattagaaaatgcattacgttggctt
tctgctattcatgaagtgacattgcgtacgcttcccgaaaatgaatatattttcccattc
agtatgccggcagggttgccaccggaaaagcaaattaaggttgcgcaattggataatccg
gaagatgtggcatatcgtgagcatttagtgaaaaactacggcaaatataaacaaatggtc
agtggtattcactataatttccaattggatccggcatttgttcaagcactttttgaagct
caaacgaaacaaacaagtgcggtggattttcagaatgatttatatctgaaaattgcgaaa
aatttccttcgctatcaatggattctgctttatttgttctctgctacgccaaccgttgat
gaaaattatttccgtgacggaacaccgcttcaacccaatcaatatgtgcgtagcttgcgt
tcgagccctttcggttatgtgaatgaacctgaaatcaaagtttctttcaatagtttacaa
tcctatgttgatagccttgagcattgggtaaatagcggcaagttgattgcagaaaaagaa
ttctattctaatgtgcgtttgcgtggtgcggcaaaagcccgtgatttactcaaaacgggg
attcaatatcttgagttccgcctctttgatctcaatccttttgcaccgtatggcattaca
ttggaagatgcgaaattcatccattatttcattttattgatggcatggttggatcatacg
gctgatcaaggtgacatcgaattaggcaaaacccgtcttgccgaagtgtcttgggaagat
cctttatcaccaacggcttacgctgtcgaaggggagttagtattacttcaaatgctgaat
atgcttgaagcacttcaagccggtgatgaaattaaagctatcgcaaaagaaaaatttgta
caatttgcgaatccgcgtgacacgctctgtgccaacgttgtcgtcgctattgatcaattc
gggggctatcagaaattaggggcggatattgcgaaaggcaataagaaaaatgcgttcgaa
cgtttctatgccttatccggttttgacaatatggaactttcgacacaggcattaatattt
gatgcaattcaaaaagggctgaagctcgagattttagacgagcgtgatcaattcctcagt
ttgcaatacggtgatcatcttgaatatgtgaaaaatggcaatatgacttcacatgatcgc
tatatttcgccattaattatggaaaataaagtggttaccaaaaaagtgttggcaaaagcc
ggttttaatgtgccgcaaagtgttgaatttacggatgtgaaaagtgcggttgaaagtttc
ccactttttgagaaccgtgcagtggtgattaaaccgaaatctacgaattttggtctggga
attacgattttccaacaaggtgtacaaaaccgcgatgattttgccaaagcggtagaaatt
gctttccgtgaagataacgaaattatgatagaagattatttagtcggtaccgaatatcgt
ttctttgtattgggcgggcaaaccttggcggtattattacgagtaccggcgaatgtcgtc
ggtgatggcgaacatactgtgaaagaattggtcgaaatgaaaaacgatcatcctttacgt
ggcgacggcagccgtaccccattgaaaaaaattgctttgggtgatattgagaaacttcaa
ttaaaagagcaaggatggacggtcgattctattccgccaagagatcttattgtgcagtta
cgggctaattcaaatattagtaccggcggcgattctatcgatatgacggaacaaatgcat
gaaagttataaacaacttgcggttgggattgccaaagcgatgggtgctgccgtttgcggt
gtggatttgattattcctgatctaaccaaaccggcggaaaataatttgcaatcatggggt
gtgattgaagcaaacttcaatccgatgatgatgatgcatattttcccttatgccggtaaa
tcccgtcgtgtcactttgaatgtactggaaatgttatttccggaactgaaagtgcgttaa
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