Rheinheimera sp. D18: E0Z06_02545
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Entry
E0Z06_02545 CDS
T05923
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rhh
Rheinheimera sp. D18
Pathway
rhh00300
Lysine biosynthesis
rhh00550
Peptidoglycan biosynthesis
rhh01100
Metabolic pathways
rhh01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rhh00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
E0Z06_02545 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
E0Z06_02545 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
E0Z06_02545 (murF)
Enzymes [BR:
rhh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
E0Z06_02545 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QBL08471
UniProt:
A0A4P6VP25
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Position
530809..532185
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AA seq
458 aa
AA seq
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MIKLNCAEIALMLDGSLVGHNVSILNVSTDSRTIANDDLFIALKGPNFDGSAFIAEVKAK
GAAAVVVEQAVNVDIPQIIVHDTHLALGQLAAAVKARLAVKTVAVTGSAGKTTVKEMIAA
ILSRRGRVLATQGNFNNDIGVPLTMLRLSEKHDYAVLELGANHQGEIAYTTALAKPDVAI
ITNVAASHLEGFGDVDGVARAKGEIFNAITEQGLAIIPADSQYCDYWLQRLAGKQVVQFS
ATKTTDYCAQAIVLDDHGCAGFELVCPQGKQFVQLTLPGKHNVSNALAAAAASIAVGASL
LDVQLGLAQMPAVKGRANINMLSPQLRLIDDTYNANVESVKAAIDLLTAFVGYRILVLGD
MAELGTDARLYHEEIGLYAQKAGVNLLFTLGVLSQSASDLFAGQGAHFSSRQALIQRLMP
IVLEQQEVTLLVKGSRSAKMELVVQDLLERCQQESHPC
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgataaaattaaattgtgcagaaattgcgttaatgctcgatggtagcttagtcggccac
aacgtcagtattttaaatgtcagtacagacagccgaactattgcgaacgacgatttgttt
atcgccttaaaaggccctaattttgatgggtcagcatttattgcagaggtaaaggctaaa
ggtgcggcagcggttgttgtagagcaagcggtaaatgtcgatattccacaaattattgtg
cacgacactcatctggcattaggccagttagcggctgcggtaaaagcccgcttagcggta
aaaacggtagcagtaactggcagtgcgggtaaaactacagtcaaagaaatgatcgcggct
atcttaagccgacgtggccgtgtgttagctacgcagggcaattttaataatgatattggc
gtaccgcttactatgttgcgtcttagcgaaaagcatgactatgccgtgcttgaactgggt
gctaatcatcaaggtgaaatagcctataccactgcgctggcaaaacccgatgttgccatt
attaccaacgttgccgcttcgcacctagagggttttggcgacgtagatggggtggcgcgg
gcaaaaggtgaaatttttaatgctattactgagcaaggtttagccattattccagccgac
agccagtattgcgattattggctacagcgtttagccggtaagcaggtagtgcagttttct
gccactaaaacgacggattactgcgcacaggcaatagttctagacgaccacggttgtgcc
ggttttgaattggtttgcccacaaggtaagcagtttgtacagttaacactgcctggtaag
cataatgtttctaatgccttagctgctgccgccgcgagcattgctgttggcgcaagctta
ctcgacgtgcaattaggtttagcgcaaatgcccgccgttaaaggccgtgccaatattaac
atgctgtcaccgcaattacgtctgattgacgatacctacaatgccaatgttgagtcagtt
aaggccgcgattgatttgttaacggcgtttgttggctatcgcatattagtgctaggcgac
atggcggaattgggtactgacgcccgtttataccatgaagagataggtttatacgcacaa
aaagcaggtgttaatctgttgttcacccttggcgtgttatcacagagcgccagcgatttg
tttgctggacaaggcgctcattttagttcgcgccaagcgcttattcagcgcttaatgcca
atagtattagaacaacaggaagtcaccctgctagtgaaaggctcgcgtagtgcgaaaatg
gaattagtcgtacaagacttgctagaaagatgtcagcaggagagtcacccatgctag
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