Rhizobium sp. AB2/73: I8E17_09875
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Entry
I8E17_09875 CDS
T10377
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rhib Rhizobium sp. AB2/73
Pathway
rhib00300
Lysine biosynthesis
rhib00550
Peptidoglycan biosynthesis
rhib01100
Metabolic pathways
rhib01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rhib00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
I8E17_09875
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
I8E17_09875
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
I8E17_09875
Enzymes [BR:
rhib01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
I8E17_09875
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UEQ82775
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Position
complement(1985728..1987188)
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AA seq
486 aa
AA seq
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MSWLWTTEDLIAAISGRFVGSLPAGITGISIDSRSIQPGEAFFAIKGDRVDGHDYANIAM
ANGAAFIVISEARLPAMGGLAVPKVVVDDVLAALARLGVAARKRTRAKIIAVTGSVGKTT
TKEMLRRALTPSGKVHASVASFNNHWGVPLTLARMPEDTDFGVFEIGMNHPEEIRPLVKM
VQPHVAIITTIAPAHLGNFNSITEIAAAKAEIFDGVVPGGHAILNHDNDQFEMLEKAAMT
AGIEHIHSFGQHAKADVRLAEFNASEENSTLWLTIGGETMEVALGAPGRHIAENALAVLG
AVMLVEADLDQAVDALADLQPEKGRGQRHKRAIGNGYFTLIDESYNANPASMRAAIALLA
TTSPQAGPGGRAGRRIAVLGDMLEMGDYAQRVHANLAGPLLAAGIEHVWLAGPEMAALRD
ELPESVHVEYHETTEELSEFALNSVAPGDVLMVKSSLGMGFGKIIAGLLDKFPAFSDTGL
HTHQGL
NT seq
1461 nt
NT seq
+upstream
nt +downstream
nt
ttgagctggctatggacaactgaggatctgatcgctgcaatctcgggccgcttcgtcgga
tcgctgcccgctggtatcacgggcatttccatagacagtcgttccatccagccgggcgag
gcctttttcgccatcaagggcgatcgtgtcgacggccatgactatgccaatatcgctatg
gcgaacggcgccgctttcatcgtgatcagtgaggcacggctgccggcgatgggcggcctg
gccgtgccgaaggtggtcgtcgatgacgtcttggcggcgcttgcgcggctcggtgttgcc
gcccgcaagcgcacgcgggcgaagatcatcgccgtcaccggttcggtcggcaagacgacg
acaaaggagatgctgcgccgcgcgctgacgccttcggggaaggtgcatgcctccgttgct
tccttcaacaatcattggggcgtgccgctgacattggcccgcatgcctgaggataccgat
ttcggcgttttcgagatcggcatgaaccatcccgaagagatcaggccgctggtcaagatg
gtgcagccgcatgtcgcgatcatcaccacgatcgcgccggcccacctcggcaatttcaac
agcatcaccgaaattgctgccgcaaaggcggagatattcgacggtgtcgtgccgggcggt
catgccatcctcaatcacgacaacgatcagttcgagatgctggagaaggctgccatgacg
gccgggatcgagcatatccatagcttcggccagcatgcgaaggccgatgtccgcctcgca
gagtttaatgcctcggaagagaattcgacactttggctgacgatcggcggcgagaccatg
gaggtcgcgcttggcgcaccggggcgtcacatcgcggaaaacgcgcttgccgtgctgggc
gccgtcatgcttgtggaggccgatctcgatcaagcggtcgatgcgctggccgacctgcag
ccggaaaagggcaggggccaacgccataagcgtgcgatcggcaacggctacttcacgctg
atcgatgaaagctacaacgccaatcctgcctccatgcgcgcggctatcgcgttgctggcg
acgacatcgccgcaggcgggaccaggcggacgggcgggcaggcggatcgccgtgctcggc
gacatgttggaaatgggggattatgcccagcgcgtgcatgccaacctcgcggggccgctg
cttgctgccggcatcgagcatgtctggctggctggtccggagatggcagctttgagggat
gagctgccggaaagcgttcatgtcgaatatcacgagacgactgaggaactctcggaattc
gcgctcaattctgtcgcccccggcgatgtcttgatggtgaaatcgtcgctgggaatgggg
tttggaaagatcattgcgggcttgcttgacaaatttcccgcattttccgacacgggcctc
cacacccatcaggggctttag
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