Rhinolophus hipposideros (lesser horseshoe bat): 308500692
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Entry
308500692 CDS
T12007
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform 1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
rhii Rhinolophus hipposideros (lesser horseshoe bat)
Pathway
rhii01521
EGFR tyrosine kinase inhibitor resistance
rhii04151
PI3K-Akt signaling pathway
rhii04217
Necroptosis
rhii04380
Osteoclast differentiation
rhii04550
Signaling pathways regulating pluripotency of stem cells
rhii04620
Toll-like receptor signaling pathway
rhii04621
NOD-like receptor signaling pathway
rhii04630
JAK-STAT signaling pathway
rhii04658
Th1 and Th2 cell differentiation
rhii04659
Th17 cell differentiation
rhii05140
Leishmaniasis
rhii05145
Toxoplasmosis
rhii05152
Tuberculosis
rhii05160
Hepatitis C
rhii05161
Hepatitis B
rhii05162
Measles
rhii05163
Human cytomegalovirus infection
rhii05164
Influenza A
rhii05165
Human papillomavirus infection
rhii05166
Human T-cell leukemia virus 1 infection
rhii05167
Kaposi sarcoma-associated herpesvirus infection
rhii05168
Herpes simplex virus 1 infection
rhii05169
Epstein-Barr virus infection
rhii05171
Coronavirus disease
rhii05200
Pathways in cancer
rhii05203
Viral carcinogenesis
rhii05212
Pancreatic cancer
rhii05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
rhii00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
308500692 (JAK1)
04151 PI3K-Akt signaling pathway
308500692 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
308500692 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
308500692 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
308500692 (JAK1)
04621 NOD-like receptor signaling pathway
308500692 (JAK1)
04658 Th1 and Th2 cell differentiation
308500692 (JAK1)
04659 Th17 cell differentiation
308500692 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
308500692 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
308500692 (JAK1)
05203 Viral carcinogenesis
308500692 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
308500692 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
308500692 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
308500692 (JAK1)
05161 Hepatitis B
308500692 (JAK1)
05160 Hepatitis C
308500692 (JAK1)
05171 Coronavirus disease
308500692 (JAK1)
05164 Influenza A
308500692 (JAK1)
05162 Measles
308500692 (JAK1)
05168 Herpes simplex virus 1 infection
308500692 (JAK1)
05163 Human cytomegalovirus infection
308500692 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
308500692 (JAK1)
05169 Epstein-Barr virus infection
308500692 (JAK1)
05165 Human papillomavirus infection
308500692 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
308500692 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
308500692 (JAK1)
05140 Leishmaniasis
308500692 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
308500692 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rhii01001
]
308500692 (JAK1)
Enzymes [BR:
rhii01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
308500692 (JAK1)
Protein kinases [BR:
rhii01001
]
Non-receptor tyrosine kinases
JAK family [OT]
308500692 (JAK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
308500692
NCBI-ProteinID:
XP_080912036
LinkDB
All DBs
Position
8:48234850..48360147
Genome browser
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLPDREPLRLSGGEYTAEEL
CIRAAQACCISPLCHNLFALYDENTKLWYAPNHTITVDDKTSVRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMIKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFQTSMLLISSENEMN
WFHPNDSGNVLYYEVMVTGNLGIQWRQKPNVIPVEKEKNKLKRKKLENKHKKDEERNKIR
EEWSNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSDHSFPSLGDLMSHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT
LVDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDAD
SSPMTLFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPSNCPEEVYQLMRKCWEFQPSNRTT
FQNLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaacataaaagaggactgcaatgctatggctttctgtgctaaaatgcgg
agctccaagaagaccgaggtgaatctggaggcccccgagccaggggtggaagtgctcttc
tacctgccggacagggagcccctccgactgagcggtggggagtacacggccgaggagctt
tgcatcagggcggcacaagcgtgctgtatctctcccctgtgtcacaacctctttgccctg
tatgatgagaacaccaagctctggtatgcgccaaatcacaccatcactgttgatgacaag
acatcggtccggctccactaccggatgaggttctatttcaccaactggcatggaaccaat
gataatgagcagtctgtgtggcgacattctccaaagaagcagaaaaatggctatgagaaa
aaaaaagttccagatgcaacccctcttcttgacgccagctccttggagtatctgtttgct
cagggccagtatgatttggtcaaatgcctggctcccatccgagaccccaagactgagcag
gatgggcatgacatcgagaacgagtgtctggggatggccgtcctggccatctcccactac
gccatgataaagaagatgcagttgccagaactccccaaggacatcagctacaagcggtat
attccagaaacattgaataagtccatcaggcagaggaaccttctcaccaggatgcggata
aataacgtcttcaaggatttcctcaaggaatttaacaacaagaccatttgtgacagcagt
gtgtccacacatgacctgaaggtgaaatacctggctacgttggagactttgacaaaacat
tatggtgctgaaatatttcagacctccatgttactgatttcatcagaaaatgagatgaat
tggtttcatccaaacgacagtggaaatgttctctactatgaagtgatggtgactggaaat
cttggaatccagtggagacagaaaccaaatgttatccctgttgaaaaggaaaaaaataaa
ctgaaacggaaaaaactggaaaataaacacaagaaggacgaggagagaaacaaaatacgg
gaagagtggagcaatttttcttacttccccgaaatcacccacatcgtaataaaggaatct
gttgtcagcattaacaagcaggacaacaaaaaaatggaactgaagctctcttcccatgag
gaggccttgtcctttgtgtccctggtagatggctactttcggctcacagcagacgcccat
cattacctctgcaccgatgtggctccccccttgatcgtccacaacatacagaacggctgt
cacggtccaatctgcacagaatacgccatcaataaattacggcaagaaggaagcgaggag
gggatgtacgtcctgcggtggagctgcaccgactttgacaacatactcatgaccgtcacc
tgctttgaaaagtctgaggtgctgggtggccagaaacagttcaagaactttcagatcgag
gtgcagaagggtcgctacagcctgcacggctcggaccacagcttccccagcctgggggac
ctcatgagccacctcaagaagcagattctgcgcacggacaacatcagcttcgtgctgaag
cgctgctgccagcccaagccccgagaaatctccaatctgctggtggctactaagaaagcc
caggagtggcagcctgtctaccccatgagtcagctgagtttcgatcggatcctgaagaaa
gacattatgcagggcgagcaccttgggagaggcacgcggacacacatctactctgggacc
ctggtggattacaaggatgacgaaggaacttcggaagagaagaggataaaagtgatcctc
aaagtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatg
atgagacaggtctcccacaaacacatcgtttacctctatggcgtctgtgtccgagatgtg
gagaatatcatggtggaagagtttgtggagggggggcccctggacctcttcatgcaccgg
aaaagtgacgtcctcaccacaccgtggaaattcaaagttgctaagcagctggccagtgcc
ctgagctacttggaggataaagacctggtccatggaaatgtgtgcactaaaaacctcctc
ctggcccgcgagggcatcgacagcgagtgcggcccattcatcaagctcagcgaccccggc
atccccatcactgtgttgtccagacaagaatgcatagaacgaatcccgtggattgctccc
gagtgtgtggaagactccaaaaacctgagtgtggccgctgacaaatggagctttggaact
acactctgggaaatctgctataatggcgagatccccctgaaagacaagacgctgattgag
aaagaaagattctatgaaagccggtgcaggccagtgacaccatcttgtaaggagctggct
gacctcatgactcgctgcatgaactatgaccccaatcagagaccctttttccgagccatc
atgagagacatcaataagctggaagagcagaatccagacattgtttcagaaaaaaagcca
gccaccgaagtggatcccacgcatttcgaaaagcggttcctaaagcggatccgtgacttg
ggagagggccactttgggaaagtcgagctctgcaggtatgaccctgaaggggacaacaca
ggggagcaggtggcggtcaaatccctgaagcctgagagtggaggcaaccacatagctgat
ctgaagaaggaaatcgagatcttaaggaacctctatcacgagaacattgtgaagtacaaa
ggcatctgcacagaagatggaggaaatggtattaagctcatcatggaatttctaccttcg
ggaagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcagtta
aaatacgctgttcagatttgtaagggcatggactatttgggttcacgacaatacgttcac
cgagacttagcagcaagaaatgtccttgttgagagtgaacaccaagtaaaaattggagac
ttcggtttaaccaaagcaattgaaactgataaggagtactacactgtcaaggacgatcgg
gacagccctgtgttttggtatgctccagaatgtttaatccagtgtaagttttatatcgcg
tctgacgtctggtcttttggagtgactctgcacgagctgctcacttactgtgatgcagac
tccagtcccatgacgttgttcctgaaaatgataggcccaactcatggccagatgacggtc
accagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccatctaactgtcca
gaagaggtttatcaacttatgagaaaatgctgggaatttcaaccatctaaccggacgact
tttcagaaccttattgaaggatttgaagcacttttaaaataa
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integrated database retrieval system
