Rhodococcus sp. M8: ISO16_05080
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Entry
ISO16_05080 CDS
T11421
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rhmm Rhodococcus sp. M8
Pathway
rhmm00300
Lysine biosynthesis
rhmm00550
Peptidoglycan biosynthesis
rhmm01100
Metabolic pathways
rhmm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rhmm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ISO16_05080
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ISO16_05080
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ISO16_05080
Enzymes [BR:
rhmm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ISO16_05080
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QPG46425
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Position
complement(1144623..1146149)
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AA seq
508 aa
AA seq
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MIPMTLARIAEVVGGTLHDVDDPAVEVTGTVEFDSRKVTPRGLFLALPGARSDGHDHAAD
AIAAGAAAVLAARPVGVPAVVVPPVPPVETNSLAFEHDPDGSGAAVLAALGALARAVVDE
LTAAGLTVVGVTGSAGKTSTKDLLAAVLAPLGPVVAPPGSFNNELGHPWTALRATTDTRF
LVLEMSARGPGHIAALATVAPPRIGVVLNVGTAHLGEFGSQEVIARTKGELVEALPAAEE
GGVAILNADDPLVAAMAPRTRARVVLVGSDPAAQVRATDVHLDEHARPTFTLVVRDDGTE
RRTTVTLAVHGEHHIGNALAAAAVALECGATPEQVATALGGAGAVSAHRMDVRTRADGVT
VVDDAYNANPDSMRAALKALVTMARAGDSPRRTWAVLGEMGELGDESVVEHDAIGRLAVR
LDVTRIVAVGATRPVRGLYQGAVMEGSWGDEASHVPDTAAAIELLERELRPGDLVLVKAS
QSVRLWTVAEAILAGTAGTAGTETEAAR
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgatgacacttgcccgcatcgcggaggtggtcggtgggacactgcacgacgtc
gacgacccggccgtcgaggtgacgggcaccgtcgagttcgactcccgcaaggtcaccccg
cgcgggctgttcctggcgctgccgggggcccgctccgacgggcacgaccacgccgccgac
gccatcgccgccggcgccgccgcggtgctcgccgcccgaccggtgggtgtgcccgccgtc
gtggtgccgccggtgccgccggtcgagaccaactcgctggccttcgaacacgaccccgac
ggctcgggtgccgccgtcctcgccgcgctgggtgccctcgcccgcgccgtggtcgacgag
ctcaccgccgccgggctgaccgtcgtcggcgtcaccggatccgcgggcaagacctccacg
aaggacctgcttgccgcggtgctcgcgccgctcggcccggtcgtcgcccctcccggctcc
ttcaacaacgagctcgggcatccgtggacggcgctgcgcgccaccaccgacacccgattc
ctggtgctggagatgtcggcccgcggacccgggcacatcgccgccctcgccaccgtcgcg
ccgccccgcatcggggtggtgctcaacgtcggcaccgcccacctgggggaattcggttcc
caggaggtcatcgcccggacgaagggggagctcgtcgaggccctgccggccgccgaggag
ggcggcgtggcgatcctcaacgcggacgaccccctggtcgccgcgatggcaccgcgcacc
cgcgcccgcgtggtgctcgtcggcagcgacccggccgcgcaggtccgggccaccgacgtc
cacctcgacgagcacgcccgtcccacgttcaccctcgtcgtgcgcgacgacggcaccgag
cgccgcaccacggtcaccctcgcggtgcacggcgagcaccacatcggcaacgccctcgcg
gccgcggccgtcgcgctcgagtgcggcgccacgcccgagcaggtcgcgaccgcgctcggc
ggtgccggcgcggtgtcggcgcaccgtatggacgtgcgcacccgtgccgacggcgtcacc
gtcgtcgacgacgcgtacaacgccaacccggactcgatgcgggcggcgctcaaggcgctg
gtgaccatggcccgcgccggcgacagcccgcgccggacctgggcggtgctgggggagatg
ggtgaactcggtgacgagtccgtcgtcgagcacgacgccatcggccggctcgcggtgcgc
ctggacgtcacccgcatcgtcgcggtcggcgcgacccgcccggtccgcggtctctaccag
ggtgcggtgatggaaggatcctggggcgacgaggcgagccacgtccccgacaccgccgcc
gcgatcgagctcctcgagcgcgagctgcggcccggcgacctggtactggtcaaggcctcg
cagtccgtccggttgtggacggtggcggaggcgatcctcgcaggaacggcgggtacggca
ggaacggaaacggaggccgcacggtga
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