Roseburia hominis: RHOM_02225
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Entry
RHOM_02225 CDS
T01621
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
rho
Roseburia hominis
Pathway
rho00470
D-Amino acid metabolism
rho00550
Peptidoglycan biosynthesis
rho01100
Metabolic pathways
rho01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rho00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
RHOM_02225
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
RHOM_02225
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
RHOM_02225
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
rho01011
]
RHOM_02225
Enzymes [BR:
rho01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
RHOM_02225
Peptidoglycan biosynthesis and degradation proteins [BR:
rho01011
]
Precursor biosynthesis
Amino acid ligase
RHOM_02225
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp_4
CPSase_L_D2
ATP-grasp_3
RimK
ATP-grasp
GARS_A
ATPgrasp_ST
Ligase_CoA
Motif
Other DBs
NCBI-ProteinID:
AEN95567
UniProt:
G2T1S3
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All DBs
Position
482410..483465
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AA seq
351 aa
AA seq
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MKIVVLAGGLSTERDVSFKTGEMVTKALRENGHQVILLDVFMGYSDKEEDLTGIFDRAEA
VSVKVAAIPETAPDLEKVKAQRKDQSDNFFGPNVIELCRMADIVFMALHGENGENGKIQA
AFDLFGIRYTGTGYLGSALAMNKGMAKQLFLENGIPTPRGTSLKRGEDAAKIETCGIHFP
CVVKPCSGGSSIGVSIVHDKAEYEQALKEAFRWENELVIEEYVKGREFSVGVIDFQALPI
IEIAPVEGFYDYKNKYKAGSTVETCPAELSEQITKEMQGYAEKVAEVLGLNTYSRTDFLL
DAEDHIFCLEANTLPGMTPTSLLPQEAKVTGVDFNQLCEKLIESSMRKYKN
NT seq
1056 nt
NT seq
+upstream
nt +downstream
nt
atgaagatagttgttttggcaggggggctcagcacagagagagatgtgtccttcaagaca
ggagagatggttacgaaagcactcagagagaacggacatcaggtaattttacttgatgtt
tttatgggatatagcgataaggaagaagatcttaccggaatttttgacagagccgaggcg
gtcagcgtcaaggtggcggcgattccggagaccgcgccggacctggaaaaagtaaaggcg
cagagaaaggatcagtcggataatttcttcggaccgaatgtcatcgagctttgccggatg
gcggacatcgtgtttatggcgcttcatggagagaacggagagaacggtaagatccaggcg
gcgtttgacctgtttggcatccgctacacaggaaccggatatctgggcagtgcgcttgcc
atgaacaaaggaatggcaaagcagctgttcctcgagaatggaatcccgacgccgagaggc
acgtccttaaagcgtggcgaggatgcggcaaagatcgagacctgtggaattcatttcccg
tgcgtggtaaagccgtgcagcggcggatcaagcatcggcgtatcgatcgtgcacgacaag
gcagaatacgagcaggcattaaaggaggcgttccgctgggagaatgagctggtcattgag
gaatatgtaaaaggaagagaattttctgtcggcgtcatcgattttcaggcgcttccgatc
atcgagatcgcgccggtggaaggcttctatgattataagaacaaatacaaagcgggaagt
acggtagagacctgcccggcggagctgtccgaacagattacaaaggaaatgcagggctat
gcagagaaggtggcagaggtgcttggactcaacacttactcgcgcacagacttccttctg
gatgcggaagatcacattttctgtctggaggcgaacacacttccgggcatgacgccgacc
agtctgctgccgcaggaggcaaaggtgaccggcgtggatttcaaccagctctgtgagaag
ctgatcgagagttccatgcgcaagtacaagaattaa
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