Roseburia hominis: RHOM_05145
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Entry
RHOM_05145 CDS
T01621
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
rho
Roseburia hominis
Pathway
rho00230
Purine metabolism
rho01100
Metabolic pathways
rho01110
Biosynthesis of secondary metabolites
Module
rho_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
rho00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
RHOM_05145
Enzymes [BR:
rho01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
RHOM_05145
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
SHOCT
GATase_3
Motif
Other DBs
NCBI-ProteinID:
AEN96148
UniProt:
G2T179
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All DBs
Position
1119415..1123218
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AA seq
1267 aa
AA seq
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MSNVRRVYVEKKPAFAVRARELEAEIRNYLGISDVKGVRELIRYDMEHVSEETYRKALVT
VFSEPPVDDVYEETFELNGARTFSVEFLPGQFDQRADSAEQCVKLLNENEEPLIRTAVTY
VIEGEISDAEFEAIKKHCINPVDSRETGLEKPQTLVQSFPEPEDVKIFDGFSAMPEAELK
ELYDSLGLAMTFKDFLHIQNYFKNEEKRDPSMTEIRVLDTYWSDHCRHTTFSTELKDVSF
DDGYYRAPMEETYQDYLATHKNLYAGRSDKFVCLMDIALMAMKRLKKEGKLMDQEESDEI
NACSIVVPIEVDGVTEEWLVNFKNETHNHPTEIEPFGGAATCLGGAIRDPLSGRTYVYQA
MRVTGAADPTVSVKDTIPGKLPQKKLVREAAHGYSSYGNQIGLATGYVKEVYHPNYVAKR
MEIGAVLGAAPRRAVQRLTSDPGDIIILLGGRTGRDGIGGATGSSKAHNTESTAVCGAEV
QKGNPPTERKIQRLFRREEVAHIIKKCNDFGAGGVSVAIGELADGLRVQLDKVPKKYAGL
DGTELAISESQERMAVVVAPEDVQKFLAFAKEENLEAVEVAVVTEEPRLVLTWRGKEVVN
LSRAFLDTNGAHQETNVAVDMPDPKENYLNKIDTPAVSEALAAGDMKKAWLAELADLNVC
SQKGLVEMFDGSIGAGSVYMPFGGKYQLTETQSMVAKIPVMTGKSDAVTMMAYGFDPYLS
SWSPYHGAVYAVLESLSRIVSAGGDYSKVRFTFQEYFRRMSEEPKRWSQPFAALLGAYNA
QIGFGLPSIGGKDSMSGSFNEIDVPPTLVSFAVDVAKEGDIITPELKAVGNQLVLFSIER
DSYDLPVYAQVMKLYAVLHELIGKGAVVSAYALDGKGLAAAVSKMAFGNKLGVTIEKEVS
EETLFAPGFGNIVAEVPVEKVGIVKETLKAAGLSGNEELVGWVNEEQSFCYGGMKLALDE
AIAAWSGTLEKVFPTRVTDNKDELDTGIYQADSIYVCKHKVAKPTVFIPVFPGTNCEYDS
ARAFERAGADTIVKVFKNLNAEDIRDSVEEFTKAIDQAQIIMFPGGFSAGDEPEGSAKFF
ATAFRNAKMTEAVMKLLNERDGLALGICNGFQALIKLGLVPYGEIRPQTADSPTLTYNTI
GRHISKMVYTKVVTNKSPWLAQAKTGEVYCNPASHGEGRFVAPKEWLEKLFANGQVATQY
VNEAGVPTMDEEWNVNGSYMAIEGITSPDGRVLGKMAHSERRDRSVAMNIYGEQDLRLFE
SGVEYFK
NT seq
3804 nt
NT seq
+upstream
nt +downstream
nt
atgagcaacgtaagacgcgtatatgtggagaaaaaaccggcatttgctgtcagagcaaga
gagctggaagcagagatcagaaattatctcggtatcagtgacgtgaagggagtgcgtgag
ctgatccgttacgatatggagcatgtatcggaggaaacctaccgcaaggctctggttacc
gttttttccgagccgccggtggacgatgtgtacgaggaaacttttgagttaaatggcgcg
agaactttttccgtagaattcctgccgggacagtttgaccagagagcggactccgccgag
cagtgcgtgaagctgttaaatgagaacgaggagccgctgatccgcacggctgtgacctat
gtgatcgagggagagatcagcgatgcagagtttgaggcgatcaaaaagcactgcatcaac
ccggttgactccagagagaccggtcttgagaagccgcagacgctggtgcagtcgttcccg
gagccagaggatgtaaagattttcgacggattttctgcgatgcctgaggcagaactgaag
gaactttatgattccctcggtctggcgatgactttcaaggactttttacatattcagaat
tattttaagaatgaggagaagcgcgacccgtccatgacggagatccgcgtattggacacc
tactggtccgatcactgccgtcatacgacgttttccacagaacttaaggacgtaagcttt
gacgacggctattaccgtgcgccgatggaggagacctatcaggattacctcgccacccat
aagaatctttacgcaggacgttcagacaaattcgtgtgcctgatggacattgccttaatg
gcgatgaagcgcctcaaaaaggagggcaagctgatggatcaggaggaatccgatgagatc
aatgcctgctcgattgtcgttccgatcgaggtggacggagtgactgaggagtggcttgta
aactttaagaacgagacacataaccacccgacagagattgaaccgttcggtggtgctgcg
acctgtctgggcggtgcgatccgtgatccgctttccggacgtacctatgtctatcaggca
atgcgtgtgaccggtgcggcagatccgacagtttccgtgaaagacacgatcccgggcaag
cttccgcagaagaagcttgtgcgcgaggcggcacacggttacagttcttatggtaaccag
atcggtctggcaaccggttatgtcaaggaggtataccatccgaattatgtggcgaagcgt
atggagatcggtgcagtgctcggtgcggctccgagacgtgcggtgcagagactgacctcc
gatccgggagacatcatcattctgcttggcggccgtaccggtcgtgacggcatcggtggt
gcgacaggttcttccaaggcacataacacagagtccaccgcagtctgcggtgcagaggtg
cagaagggtaacccgccgacagagcgcaagatccagagattattccgccgcgaggaagtg
gcgcatatcatcaagaagtgtaatgacttcggtgcaggcggtgtatcggttgccatcgga
gagctggcagacggactgcgcgtgcagctggataaggtgccgaagaaatatgcgggactt
gatggaaccgaacttgcaatctcagagtcccaggaacgtatggcggtcgtagtggcaccg
gaggatgtacagaagttccttgcatttgcgaaggaggagaatctggaagctgtcgaggtt
gcggttgtgaccgaggagccgagactggtactcacgtggagaggaaaggaagtcgtaaac
ttatcccgtgcattcctggataccaacggtgcacatcaggagaccaatgtggcagtggat
atgccggacccgaaggaaaattatctgaataagatcgatacaccggcggtttccgaggcg
ttagcagcaggcgatatgaagaaagcatggctcgcagaacttgccgacttgaatgtgtgt
tctcagaagggactggtggagatgttcgacggttccatcggagcgggaagcgtatacatg
ccgttcggtgggaaatatcagctgaccgagacacagtccatggtggcaaagattccggtg
atgaccggcaaatccgatgcagtcacgatgatggcatacggcttcgatccgtatctgtct
tcctggagcccgtatcacggtgcggtgtatgcagtgcttgagtctctgtcgagaatcgtg
tctgcaggcggcgattacagcaaggtgcgctttaccttccaggagtatttccgcaggatg
agcgaggagccgaagcgctggagtcagccgtttgctgctctgcttggcgcgtacaatgca
cagatcggcttcggactgccgtccatcggaggaaaggattccatgtccggaagcttcaac
gagatcgacgtaccgccgacactggtatcctttgccgtggatgtggcaaaagagggcgac
atcatcacgccggagcttaaggcagtgggaaatcagctggtacttttctccatcgagagg
gattcttatgatcttccggtctatgcgcaggtaatgaagctctatgcggtgctgcatgag
ctgatcggaaagggtgcggtcgtatccgcctatgcgctggatggaaaaggacttgcggcg
gcagtcagcaagatggcatttggcaataagcttggtgtgacgattgagaaggaagtgtcg
gaagagacactgtttgcaccgggatttggtaatatcgtggcggaggttccagtggagaag
gttggtattgtcaaggagacattaaaggcagcgggactttccggaaatgaggagcttgtc
ggctgggtaaatgaggaacagagcttctgctacggcggcatgaagcttgcactcgacgag
gcgatcgcagcatggagcggcacgctggagaaagtattcccgacccgcgtgacagataat
aaggacgaacttgacaccggcatctatcaggcagacagtatctatgtctgcaaacacaag
gtggcaaaaccgaccgtgtttataccggtatttccgggaacgaactgcgagtacgacagt
gcgagagcatttgagcgcgcaggtgcggacacgatcgtaaaggtattcaagaacctgaat
gcagaggacatccgcgattcggttgaggagttcacaaaggcgatcgatcaggcacagatt
atcatgttcccgggcggattctccgcgggagatgagccggagggctccgcgaagttcttt
gcgaccgcgttccgcaatgcgaagatgacagaggcggtcatgaagcttttgaacgagcgc
gacggactggcgctcggtatctgcaacggtttccaggcactgattaagctggggctggta
ccgtacggagagatccgtccgcagaccgcagattcaccgacattaacctacaacacgatc
ggccgtcatatcagcaagatggtatacacgaaggttgtgacgaacaagtccccgtggctg
gcacaggcaaagaccggcgaggtatattgcaatccggcttcccacggcgagggacgtttt
gtcgctccgaaggaatggctggagaagctgtttgcaaacggtcaggtggcaacacagtat
gtcaacgaggcgggtgttccgaccatggatgaggagtggaatgtcaacggctcctacatg
gcaatcgagggaatcacaagcccggacggaagagtgctcggcaagatggcacattcggag
cgtcgtgaccggagtgtggcgatgaatatttacggtgagcaggatttgagactgtttgag
tccggcgtggaatattttaagtaa
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